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11 p, 286.2 KB Long-term safety and efficacy of eculizumab in generalized myasthenia gravis / Muppidi, Srikanth (Stanford University School of Medicine) ; Utsugisawa, Kimiaki (Hanamaki General Hospital) ; Benatar, Michael (University of Miami Miller School of Medicine) ; Murai, Hiroyuki (International University of Health and Welfare) ; Barohn, Richard J. (University of Kansas Medical Center) ; Illa, Isabel (Hospital Universitari Vall d'Hebron) ; Jacob, Saiju (Birmingham Women's and Children's Hospital (Regne Unit)) ; Vissing, John (University of Copenhagen) ; Burns, Ted M. (University of Virginia Health System) ; Kissel, John T. (The Ohio State University) ; Nowak, Richard J. (Yale University) ; Andersen, Henning (Aarhus University Hospital (Aarhus, Dinamarca)) ; Casasnovas, Carlos (Hospital Universitari de Bellvitge) ; De Bleecker, Jan (Universitair Ziekenhuis Gent) ; Vu, Tuan H. (University of South Florida) ; Mantegazza, Renato (Fondazione IRCCS Istituto Neurologico Carlo Besta (R.M.) (Milà, Itàlia)) ; O'Brien, Fanny L. (Alexion Pharmaceuticals) ; Wang, Jing Jing (Alexion Pharmaceuticals) ; Fujita, Kenji P (Alexion Pharmaceuticals) ; Howard, James F. (University of North Carolina)
Introduction : Eculizumab is effective and well tolerated in patients with antiacetylcholine receptor antibody-positive refractory generalized myasthenia gravis (gMG; REGAIN; NCT01997229). We report an interim analysis of an open-label extension of REGAIN, evaluating eculizumab's long-term safety and efficacy. [...]
2019 - 10.1002/mus.26447
Muscle & nerve, Vol. 60 (march 2019) , p. 14-24  
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