Results overview: Found 14 records in 0.02 seconds.
Articles, 10 records found
Research literature, 4 records found
Articles 10 records found  
1.
20 p, 858.8 KB Adaptation and Conservation throughout the Drosophila melanogaster Life-Cycle / Coronado-Zamora, Marta (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Salvador-Martínez, Irepan (University College London. Department of Genetics, Evolution and Environment) ; Castellano Esteve, David (Aarhus University. Bioinformatics Research Center) ; Barbadilla, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Salazar-Ciudad, Isaac (Centre de Recerca Matemàtica)
Previous studies of the evolution of genes expressed at different life-cycle stages of Drosophila melanogaster have not been able to disentangle adaptive from nonadaptive substitutions when using nonsynonymous sites. [...]
2019 - 10.1093/gbe/evz086
Genome biology and evolution, Vol. 11, Num. 5 (May 2019) , p. 1463-1482  
2.
28 p, 2.6 MB Functional impact and evolution of a novel human polymorphic inversion that disrupts a gene and creates a fusion transcript / Puig Font, Marta (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Castellano Esteve, David (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Pantano, Lorena (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Giner Delgado, Carla (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Izquierdo, David (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Gayà Vidal, Magdalena (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Lucas Lledó, Jose Ignacio (Universitat de València. Institut Cavanilles de Biologia Evolutiva i Biodiversitat) ; Esko, Tõnu (Estonian Genome Center) ; Terao, Chikashi (Kyoto University Graduate School of Medicine) ; Matsuda, Fumihiko (Center for Genomic Medicine. Kyoto University Graduate School of Medicine) ; Cáceres Aguilar, Mario (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
Despite many years of study into inversions, very little is known about their functional consequences, especially in humans. A common hypothesis is that the selective value of inversions stems in part from their effects on nearby genes, although evidence of this in natural populations is almost nonexistent. [...]
2015 - 10.1371/journal.pgen.1005495
PLoS Genetics, Vol. 11, issue 10 (2015) , art. e1005495  
3.
6 p, 807.2 KB The Drosophila melanogaster Genetic Reference Panel / MacKay, T.F.C. (Department of Genetics. North Carolina State University) ; Richards, S. (Human Genome Sequencing Center. Baylor College of Medicine) ; Stone, E.A. (Department of Genetics. North Carolina State University) ; Barbadilla Prados, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i Microbiologia) ; Ayroles, J.F. (FAS Society of Fellows. Harvard University) ; Zhu, D. (Human Genome Sequencing Center. Baylor College of Medicine) ; Casillas Viladerrams, Sònia (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Han, Y. (Human Genome Sequencing Center. Baylor College of Medicine) ; Magwire, M.M. (Department of Genetics. North Carolina State University) ; Cridland, J.M. (Department of Ecology and Evolutionary Biology. University of California-Irvine) ; Richardson, M.F. (Faculty of Life Sciences. University of Manchester) ; Anholt, R.R.H. (Department of Biology. North Carolina State University) ; Barrón, Maite G. (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Bess, C. (Human Genome Sequencing Center. Baylor College of Medicine) ; Blankenburg, K.P. (Human Genome Sequencing Center. Baylor College of Medicine) ; Carbone, M.A. (Department of Genetics. North Carolina State University) ; Castellano Esteve, David (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Chaboub, L. (Human Genome Sequencing Center. Baylor College of Medicine) ; Duncan, L. (Department of Genetics. North Carolina State University) ; Harris, Z. (Department of Genetics. North Carolina State University) ; Javaid, M. (Human Genome Sequencing Center. Baylor College of Medicine) ; Jayaseelan, J.C. (Human Genome Sequencing Center. Baylor College of Medicine) ; Jhangiani, S.N. (Human Genome Sequencing Center. Baylor College of Medicine) ; Jordan, K.W. (Department of Genetics. North Carolina State University) ; Lara, F. (Human Genome Sequencing Center. Baylor College of Medicine) ; Lawrence, F. (Department of Genetics. North Carolina State University) ; Lee, S.L. (Human Genome Sequencing Center. Baylor College of Medicine) ; Librado, P. (Department of Genetics. Faculty of Biology. Universitat de Barcelona) ; Linheiro, R.S. (Faculty of Life Sciences. University of Manchester) ; Lyman, R.F. (Department of Genetics. North Carolina State University) ; MacKey, A.J. (Center for Public Health Genomics. University of Virginia) ; Munidasa, M. (Human Genome Sequencing Center. Baylor College of Medicine) ; Muzny, D.M. (Human Genome Sequencing Center. Baylor College of Medicine) ; Nazareth, L. (Human Genome Sequencing Center. Baylor College of Medicine) ; Newsham, I. (Human Genome Sequencing Center. Baylor College of Medicine) ; Perales, L. (Human Genome Sequencing Center. Baylor College of Medicine) ; Pu, L.L. (Human Genome Sequencing Center. Baylor College of Medicine) ; Qu, C. (Human Genome Sequencing Center. Baylor College of Medicine) ; Ràmia Jesús, Miquel (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Reid, J.G. (Human Genome Sequencing Center. Baylor College of Medicine) ; Rollmann, S.M. (Department of Biological Sciences. University of Cincinnati) ; Rozas, J. (Department of Genetics. Faculty of Biology. Universitat de Barcelona) ; Saada, N. (Human Genome Sequencing Center. Baylor College of Medicine) ; Turlapati, L. (Department of Genetics. North Carolina State University) ; Worley, K.C. (Human Genome Sequencing Center. Baylor College of Medicine) ; Wu, Y.Q. (Human Genome Sequencing Center. Baylor College of Medicine) ; Yamamoto, A. (Department of Genetics. North Carolina State University) ; Zhu, Y. (Human Genome Sequencing Center. Baylor College of Medicine) ; Bergman, C.M. (Faculty of Life Sciences. University of Manchester) ; Thornton, K.R. (Department of Ecology and Evolutionary Biology. University of California-Irvine) ; Mittelman, D. (Virginia Bioinformatics Institute. Department of Biological Sciences. Virginia Tech) ; Gibbs, R.A. (Human Genome Sequencing Center. Baylor College of Medicine)
A major challenge of biology is understanding the relationship between molecular genetic variation and variation in quantitative traits, including fitness. This relationship determines our ability to predict phenotypes from genotypes and to understand how evolutionary forces shape variation within and between species. [...]
2012 - 10.1038/nature10811
Nature, Vol. 482, issue 7384 (Feb. 2012) , p. 173-178  
4.
14 p, 1.8 MB Evolutionary and functional impact of common polymorphic inversions in the human genome / Giner Delgado, Carla (Universitat Autònoma de Barcelona. Departament de Genètica i Microbiologia) ; Villatoro, Sergi (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Lerga Jaso, Jon (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Gayà Vidal, Magdalena (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Oliva Pavía, Meritxell (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Castellano Esteve, David (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Pantano, Lorena (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Bitarello, Bárbara D. (Max-Planck-Institut für Evolutionäre Anthropologie) ; Izquierdo, David (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Noguera, Isaac (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Olalde, Iñigo (Universitat Pompeu Fabra. Institut de Biologia Evolutiva) ; Delprat, Alejandra (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Blancher, Antoine (Centre de Physiopathologie Toulouse-Purpan) ; Lalueza-Fox, Carles (Universitat Pompeu Fabra. Institut de Biologia Evolutiva) ; Esko, Tõnu (Estonian Genome Center) ; O'Reilly, Paul F. (King's College London. Institute of Psychiatry, Psychology and Neuroscience) ; Andrés, Aida M. (Max-Planck-Institut für Evolutionäre Anthropologie) ; Ferretti, Luca (University of Oxford. Big Data Institute) ; Puig Font, Marta (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Cáceres Aguilar, Mario (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
Inversions are one type of structural variants linked to phenotypic differences and adaptation in multiple organisms. However, there is still very little information about polymorphic inversions in the human genome due to the difficulty of their detection. [...]
2019 - 10.1038/s41467-019-12173-x
Nature communications, Vol. 10 (2019) , art. 4222  
5.
9 p, 341.6 KB Androgen receptor gene status in plasma DNA associates with worse outcome on enzalutamide or abiraterone for castration-resistant prostate cancer: a multi-institution correlative biomarker study / Conteduca, V. (Centre for Evolution and Cancer. The Institute of Cancer Research, London) ; Wetterskog, D. (Centre for Evolution and Cancer. The Institute of Cancer Research, London) ; Sharabiani (Royal Marsden NHS Foundation Trust. Research Data Management and Statistics Unit) ; Grande, E. (Hospital Ramon y Cajal. Departamento de Oncologia Médica) ; Fernandez Perez, M. P. (Hospital Universitario Morales Meseguer. Departamento de Hematologia y de Oncologia Médica) ; Jayaram, A. (Centre for Evolution and Cancer. The Institute of Cancer Research, London) ; Salvi, S. (Istituto Scientifico Romagnolo per lo Studio e Cura dei Tumori (IRST) IRCCS) ; Castellano, D. (Hospital Universitario 12 de Octubre. Departamento de Oncologia Médica) ; Romanel, A. (Università di Trento. Centro di Biologia Integrata) ; Lolli, C. (Istituto Scientifico Romagnolo per lo Studio e Cura dei Tumori (IRST) IRCCS) ; Casadio, V. (Istituto Scientifico Romagnolo per lo Studio e Cura dei Tumori (IRST) IRCCS) ; Gurioli, G. (Istituto Scientifico Romagnolo per lo Studio e Cura dei Tumori (IRST) IRCCS) ; Amadori, D. (Istituto Scientifico Romagnolo per lo Studio e Cura dei Tumori (IRST) IRCCS) ; Font, A. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Vazquez Estevez, S. (, Hospital Universitario Lucus Augusti. Departamento de Oncologia Médica) ; González del Alba, A. (Hospital Universitario Son Espases Mallorca. Departament d'Oncologia Médica) ; Mellado, B. (IDIBAPS Hospital Clinic. Departament d'Oncologia Médica) ; Fernandez Calvo, O. (Hospital de Ourense. Departamento de Oncologia Médica) ; Méndez Vidal, M. J. (Hospital Universitario Reina Sofía. Departamento de Oncologia Médica) ; Climent, M. A. (Instituto Valenciano de Oncología) ; Duran, I. (Instituto de Biomedicina de Sevilla) ; Gallardo, E. (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Rodriguez, A. (Hospital de León. Departamento de Oncologia Médica) ; Santander, C. (Hospital Universitario Miguel Servet. Departamento de Oncologia Médica) ; Sáez, M. I. (Hospital Regional y Hospital Virgen de la Victoria, Malaga. Departamento de Oncologia Médica) ; Puente, J. (Hospital Clínico San Carlos. Departamento de Oncologia Médica) ; Gasi Tandefelt, D. (Centre for Evolution and Cancer. The Institute of Cancer Research, London) ; Wingate, A. (Centre for Evolution and Cancer. The Institute of Cancer Research, London) ; Dearnaley, D. (Royal Marsden NHS Foundation Trust. Academic Urology Unit) ; Demichelis, F. (Università di Trento. Centro di Biologia Integrata) ; De Giorgi, U. (Istituto Scientifico Romagnolo per lo Studio e Cura dei Tumori (IRST) IRCCS) ; Gonzalez Billalabeitia, E. (Hospital Universitario Morales Meseguer. Departamento de Hematologia y de Oncologia Médica) ; Attard, G. (Centre for Evolution and Cancer. The Institute of Cancer Research, London) ; Spanish Oncology Genitourinary Group ; Universitat Autònoma de Barcelona
2632A>G (p. T878A)] were observed in eight (11%) post-docetaxel but no chemotherapy-naı¨ve abiraterone-treated patients and were also associated with worse OS (HR 3. 26; 95% CI 1. 47-not reached; P¼0. [...]
Background: There is an urgent need to identify biomarkers to guide personalized therapy in castration-resistant prostate cancer (CRPC). We aimed to clinically qualify androgen receptor (AR) gene status measurement in plasma DNA using multiplex droplet digital PCR (ddPCR) in pre- and post-chemotherapy CRPC. [...]

2017
Annals of oncology, Núm. 28 (2017) , p. 1508-1516  
6.
31 p, 953.6 KB Spherical microaggregation : anonymizing sparse vector spaces / Abril Castellano, Daniel (Institut d'Investigació en Intel·ligència Artificial) ; Navarro-Arribas, Guillermo (Universitat Autònoma de Barcelona. Departament d'Enginyeria de la Informació i de les Comunicacions) ; Torra i Reventós, Vicenç (Institut d'Investigació en Intel·ligència Artificial)
Unstructured texts are a very popular data type and still widely unexplored in the privacy preserving data mining field. We consider the problem of providing public information about a set of confidential documents. [...]
2015 - 10.1016/j.cose.2014.11.005
Computers & Security, Vol. 49 (March 2015) , p. 28-44  
7.
12 p, 5.3 MB Novel potential predictive markers of sunitinib outcomes in long-term responders versus primary refractory patients with metastatic clear-cell renal cell carcinoma / Puente, Javier (Hospital Clínico Universitario San Carlos) ; Laínez, Nuria (Medical Oncology Department, Complejo Hospitalario de Navarra, Pamplona, Spain) ; Dueñas, Marta (CIBERONC, Spain) ; Méndez-Vidal, María José (Medical Oncology Department, Hospital Universitario Reina Sofía, Córdoba, Spain) ; Esteban, Emilio (Medical Oncology Department, Hospital Universitario Central de Asturias, Oviedo, Spain) ; Castellano, Daniel (Medical Oncology Department, and Instituto Investigación Biomédica, Hospital Universitario 12 de Octubre, Madrid, Spain) ; Martinez-Fernández, Mónica (CIBERONC, Spain) ; Basterretxea, Laura (Medical Oncology Department, Hospital Donostia, Donostia, Spain) ; Juan-Fita, María José (Medical Oncology Department, Instituto Valenciano de Oncología, Valencia, Spain) ; Antón, Luis (Medical Oncology Department, Complejo Hospitalario Universitario de A Coruña, A Coruña, Spain) ; León, Luis (Promoción e Planificación da Investigación Sanitaria, Axencia de Coñecemento en Saúde, Santiago de Compostela, Spain) ; Lambea, Julio (Medical Oncology Department, Hospital Clínico de Zaragoza, Zaragoza, Spain) ; Pérez-Valderrama, Begoña (Medical Oncology Department, Hospital Universitario Virgen del Rocío, Sevilla, Spain) ; Vázquez, Sergio (Medical Oncology Department, Hospital Universitario Lucus Augusti, Lugo, Spain) ; Suarez, Cristina (Universitat Autònoma de Barcelona) ; del Muro, Xavier Garcia (Institut Català d'Oncologia, Hospital Duran i Reynals) ; Gallardo, Enrique (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Maroto, José Pablo (Institut d'Investigació Biomèdica Sant Pau) ; Samaniego, M Luz (Statistical Department, Trial Form Support TFS people, Madrid, Spain) ; Suárez-Paniagua, Beatriz (Oncology Medical Department, Trial Form Support, Madrid, Spain) ; Sanz, Julián (Pathology Department, Hospital Clínico Universitario San Carlos, Madrid, Spain) ; Paramio, Jesús M. (CIBERONC, Spain) ; Universitat Autònoma de Barcelona
Several potential predictive markers of efficacy of targeted agents in patients with metastatic renal cell carcinoma (mRCC) have been identified. Interindividual heterogeneity warrants further investigation. [...]
2017 - 10.18632/oncotarget.16494
Oncotarget, Vol. 8 (march 2017) , p. 30410-30421  
8.
14 p, 652.3 KB Adaptive evolution is substantially impeded by Hill-Robertson interference in Drosophila / Castellano Esteve, David (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Coronado-Zamora, Marta (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Campos, Jose L. (University of Edinburgh. Institute of Evolutionary Biology, School of Biological Sciences) ; Barbadilla Prados, Antonio (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Eyre-Walker, Adam (University of Sussex. Centre for the Study of Evolution, School of Life Sciences) ; Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia
Hill-Robertson interference (HRi) is expected to reduce the efficiency of natural selection when two or more linked selected sites do not segregate freely, but no attempt has been done so far to quantify the overall impact of HRi on the rate of adaptive evolution for any given genome. [...]
2015 - 10.1093/molbev/msv236
Molecular biology and evolution, Vol. 33, Núm. 2 (October 2015) , p. 442-455  
9.
11 p, 912.9 KB Evaluation of the efficacy and safety of lanreotide in combination with targeted therapies in patients with neuroendocrine tumours in clinical practice : a retrospective cross-sectional analysis / Capdevila, Jaume (Hospital Universitari Vall d'Hebron) ; Sevilla, Isabel (Hospital Universitario Virgen de la Victoria) ; Alonso, Vicente (Medical Oncology Department, Hospital Universitario Miguel Servet) ; Antón Aparicio, Luís (Complejo Hospitalario Universitario A Coruña) ; Jiménez Fonseca, Paula (Hospital Universitario Central de Asturias) ; Grande, Enrique (Hospital Universitario Ramón y Cajal) ; Reina, Juan José (Hospital Universitario Virgen de la Macarena) ; Manzano, José Luís (Hospital Universitari Vall d'Hebron) ; Alonso Lájara, Juan Domingo (Hospital Universitario Virgen de la Arrixaca) ; Barriuso, Jorge (Hospital Universitario La Paz) ; Castellano, Daniel (Hospital Universitario 12 de Octubre) ; Medina, Javier (Complejo Hospitalario de Toledo) ; López, Carlos (Hospital Universitario Marqués de Valdecilla) ; Segura, Ángel (Hospital Universitario La Fe University Hospital) ; Carrera, Sergio (Hospital Universitario de Cruces) ; Crespo, Guillermo (Hospital Universitario de Burgos) ; Fuster, José (Hospital Universitario Son Dureta) ; Munarriz, Javier (Hospital Provincial de Castellón) ; García Alfonso, Pilar (Hospital Gregorio Marañón (Madrid)) ; Universitat Autònoma de Barcelona
Based on the mechanism of action, combining somatostatin analogues (SSAs) with mTOR inhibitors or antiangiogenic agents may provide synergistic effects for the treatment of patients with neuroendocrine tumours (NETs). [...]
2015 - 10.1186/s12885-015-1512-6
BMC Cancer, Vol. 15 (july 2015)  
10.
32 p, 660.1 KB Supervised learning using a symmetric bilinear form for record linkage / Abril Castellano, Daniel (Institut d'Investigació en Intel·ligència Artificial (IIIA-CSIC)) ; Torra i Reventós, Vicenç, dir. (Institut d'Investigació en Intel·ligència Artificial (IIIA-CSIC)) ; Navarro-Arribas, Guillermo (Universitat Autònoma de Barcelona. Departament d'Enginyeria de la Informació i de les Comunicacions)
Record Linkage is used to link records of two different files corresponding to the same individuals. These algorithms are used for database integration. In data privacy, these algorithms are used to evaluate the disclosure risk of a protected data set by linking records that belong to the same individual. [...]
2015 - 10.1016/j.inffus.2014.11.004
Information fusion, Vol. 26 (Novembre 2015) , p. 144-153  

Research literature 4 records found  
1.
267 p, 6.3 MB Estimación de la huella de la selección natural y el efecto Hill-Robertson a lo largo del genoma de Drosophila melanogaster / Castellano Esteve, David ; Barbadilla Prados, Antonio, dir. ; Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia
La presente tesis es un estudio exhaustivo de genómica de poblaciones en la especie modelo Drosophila melanogaster la cual combina aproximaciones bioinformáticas y teórico-estadísticas. El objetivo de este estudio es doble, queremos estimar la importancia relativa de distintos regímenes de selección natural y el impacto del efecto Hill-Robertson a lo largo del genoma de D. [...]
The present thesis is a comprehensive population genomic study in the model species Drosophila melanogaster which combines bioinformatic and theoretical-statistical approaches. The purpose of this study is two-fold, we want to estimate the relative importance of different regimes of natural selection and the impact of the Hill-Robertson effect along the genome of D. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2016  
2.
1 p, 2.3 MB The box tree moth, Cydalima perspectalis Walker 1859 : a real threat in Catalonia / Castellano Franco, David ; García del Pino, Fernando, dir. (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2015
Grau en Biologia Ambiental [813]  
3.
47 p, 911.1 KB Introducción a la estadística bayesiana / Castellano Marrero, Dailos ; Bardina i Simorra, Xavier, dir. (Universitat Autònoma de Barcelona. Departament de Matemàtiques) ; Universitat Autònoma de Barcelona. Facultat de Ciències
El objetivo del presente trabajo es explicar de manera detallada y paso a paso diferentes técnicas utilizadas para estimar estadísticos y realizar contrastes de hipótesis referentes a proporciones y medias. [...]
L'objectiu del present treball és explicar de manera detallada i pas a pas diferents tècniques utilitzades per estimar estadístics i realitzar contrastos d'hipòtesis referents a proporcions i mitjanes. [...]

2015
Grau en Estadística Aplicada [973]  
4.
173 p, 2.7 MB Privacy protection methods for documents and risk evaluation for microdata / Abril Castellano, Daniel ; Torra Reventós, Vicenç, dir. ; Herrera-Joancomartí, Jordi (Universitat Autònoma de Barcelona. Departament d'Enginyeria de la Informació i de les Comunicacions) ; Universitat Autònoma de Barcelona. Departament d'Enginyeria de la Informació i de les Comunicacions
La capacitat de recollir i emmagatzemar informació per agencies d'estadística, governs o individus ha creat grans oportunitats d'anàlisi de les dades i la creació de models basats en el coneixent. [...]
The capability to collect and store digital information by statistical agencies, governments or individuals has created huge opportunities to analyze and build knowledge-based models. With the rise of Internet many services and companies have exploited these opportunities collecting huge amounts of data, which most of the cases are considered confidential. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2015  

See also: similar author names
3 Castellano, D.
2 Castellano, Daniel
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