Results overview: Found 20 records in 0.02 seconds.
Articles, 13 records found
Research literature, 5 records found
Course materials, 2 records found
Articles 13 records found  1 - 10next  jump to record:
1.
4 p, 966.2 KB A hypothesis explaining why so many pathogen virulence proteins are moonlighting proteins / Franco-Serrano, Luís (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Cedano Rodríguez, Juan Antonio (Universidad de la República Regional Norte-Salto. Laboratorio de Inmunología) ; Pérez-Pons, Josep A. (Josep Antoni) (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Mozo Villarias, Ángel (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Piñol Ribas, Jaume (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Amela, Isaac (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Querol Murillo, Enric (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
Moonlighting or multitasking proteins refer to those proteins with two or more functions performed by a single polypeptide chain. Proteins that belong to key ancestral functions and metabolic pathways such as primary metabolism typically exhibit moonlighting phenomenon. [...]
2018 - 10.1093/femspd/fty046
Pathogens and disease, Vol. 76, issue 5 (July 2018)  
2.
4 p, 947.1 KB MultitaskProtDB-II : an update of a database of multitasking/moonlighting proteins / Franco-Serrano, Luís (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Hernández, Sergio (Universitat Autònoma de Barcelona. Departamento de Bioquímia i Biologia Molecular) ; Calvo, Alejandra (Universidad de la República Regional Norte-Salto. Laboratorio de Inmunología) ; Severi, María A. (Universidad de la República Regional Norte-Salto. Laboratorio de Inmunología) ; Ferragut, Gabriela (Universidad de la República Regional Norte-Salto. Laboratorio de Inmunología) ; Pérez-Pons, Josep A. (Josep Antoni) (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Piñol Ribas, Jaume (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Pich, Òscar M. (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Mozo Villarias, Ángel (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Amela, Isaac (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Querol Murillo, Enrique (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Cedano Rodríguez, Juan Antonio (Universidad de la República Regional Norte-Salto. Laboratorio de Inmunología)
Multitasking, or moonlighting, is the capability of some proteins to execute two or more biological functions. MultitaskProtDB-II is a database of multifunctional proteins that has been updated. In the previous version, the information contained was: NCBI and UniProt accession numbers, canonical and additional biological functions, organism, monomeric/oligomeric states, PDB codes and bibliographic references. [...]
2017 - 10.1093/nar/gkx1066
Nucleic acids research, Vol. 46, Database issue D645–D648 (2018) , p. D645-D648  
3.
16 p, 3.2 MB Bioinformatics and moonlighting proteins / Hernández, Sergio (Universitat Autònoma de Barcelona. Departamento de Bioquímia i Biologia Molecular) ; Franco-Serrano, Luís (Universitat de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Calvo, Alejandra (Universidad de la República Regional Norte-Salto. Laboratorio de Inmunología) ; Ferragut, Gabriela (Universidad de la República Regional Norte-Salto. Laboratorio de Inmunología) ; Hermoso, Antoni (Universitat de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Amela, Isaac (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Gómez, Antonio (Institut d'Investigació Biomèdica de Bellvitge) ; Querol Murillo, Enrique (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Cedano Rodríguez, Juan Antonio (Universidad de la República Regional Norte-Salto. Laboratorio de Inmunología)
Multitasking or moonlighting is the capability of some proteins to execute two or more biochemical functions. Usually, moonlighting proteins are experimentally revealed by serendipity. For this reason, it would be helpful that Bioinformatics could predict this multifunctionality, especially because of the large amounts of sequences from genome projects. [...]
2015 - 10.3389/fbioe.2015.00090
Frontiers in Bioengineering and Biotechnology, Vol. 3 (June 2015) , art. 90  
4.
2 p, 152.1 KB MGDB : crossing the marker genes of a user microarray with a database of public-microarrays marker genes / Huerta Casado, Mario (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Munyi, Marc (Universitat Autònoma de Barcelona. Escola d'Enginyeria) ; Expósito Pérez, David (Universitat Autònoma de Barcelona. Escola d'Enginyeria) ; Querol Murillo, Enrique (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Cedano Rodríguez, Juan Antonio (Universidad de la República Regional Norte-Salto. Laboratorio de Inmunología)
Summary: The microarrays performed by scientific teams grow exponentially. These microarray data could be useful for researchers around the world, but unfortunately they are underused. To fully exploit these data, it is necessary (i) to extract these data from a repository of the high-throughput gene expression data like Gene Expression Omnibus (GEO) and (ii) to make the data from different microarrays comparable with tools easy to use for scientists. [...]
2013 - 10.1093/bioinformatics/btu109
Bioinformatics, Vol. 30, issue 12 (June 2014) , p. 1780–1781, p. 1780-1781  
5.
4 p, 2.6 MB MultitaskProtDB : a database of multitasking proteins / Hernández, Sergio (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Ferragut, Gabriela (Universidad de la República Regional Norte-Salto. Laboratorio de Inmunología) ; Amela, Isaac (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Pérez-Pons, Josep A. (Josep Antoni) (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Piñol Ribas, Jaume (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Mozo Villarias, Angel (Universitat de Lleida. Departament de Medicina Experimental) ; Cedano Rodríguez, Juan Antonio (Universidad de la República Regional Norte-Salto. Laboratorio de Inmunología) ; Querol Murillo, Enrique (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
We have compiled MultitaskProtDB, available online at , to provide a repository where the many multitasking proteins found in the literature can be stored. Multitasking or moonlighting is the capability of some proteins to execute two or more biological functions. [...]
2013 - 10.1093/nar/gkt1153
Nucleic acids research, Vol. 42, Database issue D517–D520 (2014)  
6.
5 p, 243.9 KB Biological activities of histidine-rich peptides; merging biotechnology and nanomedicine / Ferrer Miralles, Neus (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Corchero Nieto, José Luis (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Kumar, Pradeep (CSIR-Institute of Genomics and Integrative Biology) ; Cedano Rodríguez, Juan Antonio (Universidad de la República (Uruguay).) ; Gupta, Kailash C (CSIR-Indian Institute of Toxicology Research) ; Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Vázquez Gómez, Esther (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Histidine-rich peptides are commonly used in recombinant protein production as purification tags, allowing the one-step affinity separation of the His-tagged proteins from the extracellular media or cell extracts. [...]
2011 - 10.1186/1475-2859-10-101
Microbial cell factories, Vol. 10 (2011) , art. 101  
7.
11 p, 1.3 MB Gene ontology function prediction in Mollicutes using protein-protein association networks / Gómez, Antonio (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Cedano Rodríguez, Juan Antonio (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Amela, Isaac (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Planas, Antoni (Institut Químic de Sarrià) ; Piñol Ribas, Jaume (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Querol Murillo, Enrique (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
Many complex systems can be represented and analysed as networks. The recent availability of large-scale datasets, has made it possible to elucidate some of the organisational principles and rules that govern their function, robustness and evolution. [...]
2011 - 10.1186/1752-0509-5-49
BMC systems biology, Vol. 5 (April 2011) , art. 49  
8.
8 p, 741.7 KB PCOPGene-Net : holistic characterisation of cellular states from microarray data based on continuous and non-continuous analysis of gene-expression relationships / Huerta Casado, Mario (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Cedano Rodríguez, Juan Antonio (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Peña, Dario (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Rodriguez, Antonio (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Querol Murillo, Enrique (Instituto de Biotecnología y Biomedicina "Vicent Villar Palasi")
Microarray technology is so expensive and powerful that it is essential to extract maximum value from microarray data, specially from large-sample-series microarrays. Our web tools attempt to respond to these researchers' needs by facilitating the possibility to test and formulate from a hypothesis to entire models under a holistic point of view. [...]
2009 - 10.1186/1471-2105-10-138
BMC Bioinformatics, Vol. 10 (2009) , art. 138  
9.
7 p, 953.8 KB NCR-PCOPGene : An Exploratory Tool for Analysis of Sample-Classes Effect on Gene-Expression Relationships / Cedano Rodríguez, Juan Antonio (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Huerta Casado, Mario (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Querol Murillo, Enrique (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular
Background. Microarray technology is so expensive and powerful that it is essential to extract maximum value from microarray data. Our tools allow researchers to test and formulate from a hypothesis to entire models. [...]
2008
Advances in bioinformatics, Vol. 2008 (Desember 2008) , art. 789026  
10.
8 p, 354.0 KB Pathogen Proteins Eliciting Antibodies Do Not Share Epitopes with Host Proteins : A Bioinformatics Approach / Amela, Isaac (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Cedano Rodríguez, Juan Antonio (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Querol Murillo, Enrique (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular
The best way to prevent diseases caused by pathogens is by the use of vaccines. The advent of genomics enables genome-wide searches of new vaccine candidates, called reverse vaccinology. The most common strategy to apply reverse vaccinology is by designing subunit recombinant vaccines, which usually generate an humoral immune response due to B-cell epitopes in proteins. [...]
2007 - 10.1371/journal.pone.0000512
PloS one, Vol. 2 (June 2007) , p. e512  

Articles : 13 records found   1 - 10next  jump to record:
Research literature 5 records found  
1.
221 p, 5.5 MB Solving the glucocorticoid paradox in cancer using expression data / Huerta Casado, Mario ; Querol Murillo, Enrique, dir. ; Cedano Rodriguez, Juan Antonio, dir. ; Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular
Els glucocorticoides s'utilitzen comunament com a tractament adjuvant per tractar efectes secundaris i tenen una activitat antiproliferativa en diversos tumors però, d'altra banda, el seu efecte proliferatiu s'ha documentat en diversos estudis i en alguns d'ells implica la propagació del càncer. [...]
Glucocorticoids are commonly used as an adjuvant treatment for side-effects and have anti-proliferative activity in several tumours. Inspite of this fact, there has been reported a proliferative effect in several studies, that some of them involving the spread of cancer. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2016  
2.
135 p, 5.5 MB Análisis bioinformático de las proteínas multifuncinales (Moonlighting) / Hernández Ranzani, Sergio ; Querol Murillo, Enrique, dir. ; Cedano Rodríguez, Juan Antonio, dir. ; Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular
Moonlighting es la capacidad de algunas proteínas para ejecutar dos o más funciones bioquímicas. En general, las proteínas multifuncionales se identifican experimentalmente por casualidad (serendipia). [...]
Multitasking or moonlighting is the capability of some proteins to execute two or more biochemical functions. Usually, moonlighting proteins are experimentally revealed by serendipity. For this reason, it would be helpful that Bioinformatics could predict this multifunctionality, especially because of the large amounts of sequences from genome projects. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2016  
3.
114 p, 1.5 MB Bioinformatic Study of Antigen Presentation by HLA class II / Muñoz Torres, Pau Marc ; Daura, Xavier, dir. ; Cedano, Juan A, dir. ; Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí"
Entendre quin és el cribratge al que estan sotmesos els pèptids abans de poder-se unir a les molècules del complex major d'histocompatibilitat classe II o major histocompatibility complex class II en angles (MHC classe II o HLA classe II en humans) per a més tard ser presentats als limfòcits T és especialment rellevant per les seves implicacions en salut, a l'estar involucrats en diferents processos relacionats amb la defensa de l'organisme, des de la resposta davant d'infeccions a les reaccions autoimmunitàries, passant pel reconeixement de les cèl·lules cancerígenes. [...]
Understanding how peptides are selectively bound and presented by major histocompatibility complex class II molecules (MHC class II or HLA class II in humans) is of outmost importance for its broad implications in human health, from infection to autoimmunity or cancer. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2014  
4.
174 p, 2.7 MB Bioinformatics approaches to protein interaction and complexes : application to pathogen-host epitope mimicry and to Fe-S cluster biogenesis model / Amela Abellan, Isaac ; Querol Murillo, Enrique, dir. (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Cedano Rodríguez, Juan Antonio, dir. (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí"
Les interaccions antigen/anticòs són un dels tipus més interessants d'interaccions proteiques. La millor manera de prevenir les malalties causades per patògens és mitjançant l'ús de vacunes. L'aparició de la genòmica permet fer cerques a tot el genoma de nous candidats vacunals, tècnica anomenada vaccinologia inversa. [...]
Antigen/antibody interactions are one of the most interesting kinds of protein interactions. The best way to prevent diseases caused by pathogens is by the use of vaccines. The advent of genomics enables genome-wide searches of new vaccine candidates, called reverse vaccinology. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2013  
5.
24 p, 459.7 KB Rediseño de la eficiencia catalítica y de la termorresistencia de la [Beta](1-->3)(1-->4)glucanasa de Bacillus licheniformis / Cedano Rodríguez, Juan Antonio ; Querol Murillo, Enrique, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Planas i Sauter, Antoni, dir.
Introducción Las b(lŸ3)(lŸ4) glucanasas son enzimas de gran interés biotecnólogico tanto en la industria cervezera como en la de fabricación de piensos. Los objetivos de esta tesis han sido: rediseñar la glucanasa de bacillus licheniformis con objeto de tratar de mejorar la actividad enzimática y determinar la función del lazo mayor del centro activo en dicho proceso, así como analizar y rediseñar la estabilidad térmica del enzima, en particular determinar la influencia del lazo mayor en la desnaturalización térmica, relacionándolo con el proceso y tipo de plegamiento. [...]
Introduction The (l-3)(l-4) glucanases are enzymes of great biotechnologyc interest in the brewery industry and in the manufacture of fodder. One objective of this thesis is to redesign the glucanase of bacillus licheniformis trying to improve its enzymatic activity to determine the function that the big loop, situated in the active centre, in this process. [...]

Bellaterra : Universitat Autònoma de Barcelona, 2003
4 documents

Course materials 2 records found  
1.
3 p, 47.4 KB Bioinformàtica [25422] / Barbadilla Prados, Antonio ; Pérez-Pons, Josep A. (Josep Antoni) (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Gibert, Isidre ; Ponte Marull, Inmaculada ; Cedano Rodríguez, Juan Antonio ; Universitat Autònoma de Barcelona. Facultat de Ciències
2003-04
Llicenciat en Biotecnologia [529]  
2.
3 p, 143.7 KB Bioinformàtica [25422] / Barbadilla Prados, Antonio ; Pérez-Pons, Josep A. (Josep Antoni) (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Gibert, Isidre ; Ponte Marull, Inmaculada ; Cedano Rodríguez, Juan Antonio ; Universitat Autònoma de Barcelona. Facultat de Biociències
2006-07
Llicenciat en Biotecnologia [529]  

See also: similar author names
3 Cedano, Juan
1 Cedano, Juan A,
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