Results overview: Found 4 records in 0.02 seconds.
Articles, 4 records found
Articles 4 records found  
1.
19 p, 418.6 KB Binimetinib, Encorafenib, and Cetuximab Triplet Therapy for Patients With BRAF V600E-Mutant Metastatic Colorectal Cancer : Safety Lead-In Results From the Phase III BEACON Colorectal Cancer Study / Van Cutsem, Eric (University Hospitals Gasthuisberg Leuven and KU Leuven, Leuven, Belgium) ; Huijberts, Sanne (Netherlands Cancer Institute, Amsterdam, the Netherlands) ; Grothey, Axel (West Cancer Center, Germantown, TN) ; Yaeger, Rona (Memorial Sloan Kettering Cancer Center, New York, NY) ; Cuyle, Pieter-Jan (Imelda General Hospital, Bonheiden, Belgium; University Hospitals Gasthuisberg, Leuven, Belgium) ; Elez, Elena (VHIO) ; Fakih, Marwan (City of Hope Comprehensive Cancer Center, Duarte, CA) ; Montagut, Clara (Institut Hospital del Mar d'Investigacions Mèdiques) ; Peeters, Marc (Antwerp University Hospital, Edegem, Belgium) ; Yoshino, Takayuki (National Cancer Center Hospital East, Kashiwa, Japan) ; Wasan, Harpreet (Hammersmith Hospital, Imperial College London, London, United Kingdom) ; Desai, Jayesh (Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia) ; Ciardiello, Fortunato (University of Campania "Luigi Vanvitelli," Naples, Italy) ; Gollerkeri, Ashwin (Array BioPharma Inc, Boulder, CO) ; Christy-Bittel, Janna (Array BioPharma Inc, Boulder, CO) ; Maharry, Kati (Array BioPharma Inc, Boulder, CO) ; Sandor, Victor (Array BioPharma Inc, Boulder, CO) ; Schellens, Jan H.M. (Utrecht University, Utrecht, the Netherlands) ; Kopetz, Scott (The University of Texas MD Anderson Cancer Center, Houston, TX) ; Tabernero, Josep (Universitat Autònoma de Barcelona. Departament de Medicina) ; VHIR Vall d'Hebron Institut de Recerca
To determine the safety and preliminary efficacy of selective combination targeted therapy for BRAF V600E-mutant metastatic colorectal cancer (mCRC) in the safety lead-in phase of the open-label, randomized, three-arm, phase III BEACON Colorectal Cancer trial ( identifier: ; European Union Clinical Trials Register identifier: EudraCT2015-005805-35). [...]
2019 - 10.1200/JCO.18.02459
Journal of Clinical Oncology, Vol. 37 (march 2019) , p. 1460-1469  
2.
9 p, 325.6 KB Nintedanib for the treatment of patients with refractory metastatic colorectal cancer (LUME-Colon 1) : a phase III, international, randomized, placebo-controlled study / Van Cutsem, E (Division of Digestive Oncology, University Hospitals Gasthuisberg Leuven and KU Leuven, Leuven, Belgium) ; Yoshino, T (Department of Gastrointestinal Oncology, National Cancer Center Hospital East, Chiba, Japan) ; Lenz, H J (Division of Medical Oncology, Norris Comprehensive Cancer Center, Los Angeles, USA) ; Lonardi, S (Medical Oncology Unit 1, Department of Clinical and Experimental Oncology, Istituto Oncologico Veneto - IRCCS, Padua) ; Falcone, A (Department of Translational Research on New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy) ; Limón, M L (Department of Medical Oncology, Hospital Universitario Virgen del Rocio, Seville, Spain) ; Saunders, M (Department of Clinical Oncology, The Christie NHS Foundation Trust, Manchester, UK) ; Sobrero, A (Department of Medical Oncology, Azienda Ospedaliera San Martino, Genoa, Italy) ; Park, Y S (Department of Hematology and Oncology, Samsung Medical Center, Seoul, South Korea) ; Ferreiro, R (Department of Clinical Oncology, Ramón y Cajal Hospital, Madrid, Spain) ; Hong, Y S (Department of Oncology, Asan Medical Center, Seoul, South Korea) ; Tomasek, J (Department of Complex Oncology Care, Masaryk Memorial Cancer Institute, Brno, Czech Republic) ; Taniguchi, H (Department of Clinical Oncology, Aichi Cancer Center Hospital, Nagoya, Japan) ; Ciardiello, F (Oncologia Medica, Seconda Università deli Studi di Napoli, Naples, Italy) ; Stoehr, J (Boehringer Ingelheim, Pharma GmbH & Co. KG, Biberach, Germany) ; Oum'Hamed, Z (Boehringer Ingelheim France S.A.S, Reims, France) ; Vlassak, S (SCS Boehringer Ingelheim Comm.V, Brussels, Belgium) ; Studeny, M (Division of Medicine/Clinical Development Department, Boehringer Ingelheim, Vienna, Austria) ; Argiles, G (VHIO Vall d'Hebron Institut d'Oncologia) ; Universitat Autònoma de Barcelona
Angiogenesis is critical to colorectal cancer (CRC) growth and metastasis. Phase I/II studies have demonstrated the efficacy of nintedanib, a triple angiokinase inhibitor, in patients with metastatic CRC. [...]
2018 - 10.1093/annonc/mdy241
Annals of oncology, Vol. 29 (july 2018) , p. 1955-1963  
3.
10 p, 1016.0 KB Global cancer control : responding to the growing burden, rising costs and inequalities in access / Prager, Gerald W (Medical University of Vienna) ; Braga, Sofia (Instituto CUF Oncologia) ; Bystricky, Branislav (Faculty Hospital Trencin) ; Qvortrup, Camilla (Odense University Hospital. Department of Oncology) ; Criscitiello, Carmen (Istituto Europeo di Oncologia) ; Esin, Ece (Ankara Oncology Education and Research Hospital) ; Sonke, Gabe S (Netherlands Cancer Institute) ; Argilés Martínez, Guillem (Vall d'Hebron Institut d'Oncologia) ; Frenel, Jean-Sebastian (Institut de Cancerologie de l'Ouest Saint-Herblain) ; Karamouzis, Michalis (National and Kapodistrian University of Athens) ; Strijbos, Michiel (AZ KLINA Hospitals) ; Yazici, Ozan (Ankara Numune Education and Research Hospital) ; Bossi, Paolo (Fondazione IRCCS Istituto Nazionale Tumori Milano) ; Banerjee, Susana (Royal Marsden Hospital NHS Foundation Trust) ; Troiani, Teresa (Università degli Studi della Campania Luigi Vanvitelli) ; Eniu, Alexandru (Cancer Institute "Ion Chiricuta") ; Ciardiello, Fortunato (Università degli Studi della Campania Luigi Vanvitelli) ; Taberneroo, J (Universitat Autònoma de Barcelona.Departament de Medicina) ; Zielinski, Christoph C (Medical University Vienna, General Hospital, and Vienna Cancer Center) ; Casali, Paolo G (Istituto Nazionale Tumori) ; Cardoso, Fatima (Champalimaud Clinical Center) ; Douillard, Jean-Yves (European Society for Medical Oncology) ; Jezdic, Svetlana (European Society for Medical Oncology) ; McGregor, Keith (European Society for Medical Oncology) ; Bricalli, Gracemarie (European Society for Medical Oncology) ; Vyas, Malvika (European Society for Medical Oncology) ; Ilbawi, André (Disability, Violence and Injury Prevention (NVI), World Health Organization)
The cancer burden is rising globally, exerting significant strain on populations and health systems at all income levels. In May 2017, world governments made a commitment to further invest in cancer control as a public health priority, passing the World Health Assembly Resolution 70. [...]
2018 - 10.1136/esmoopen-2017-000285
ESMO Open, Vol. 3 (february 2018)  
4.
8 p, 207.5 KB Phase I study of FOLFIRI plus pimasertib as second-line treatment for KRAS -mutated metastatic colorectal cancer / Macarulla Mercadé, Teresa (Vall d'Hebron Institut d'Oncologia (VHIO)) ; Cervantes, A (Universidad de Valencia. Biomedical Research Institute (INCLIVA)) ; Taberneroo, J (Vall d'Hebron Institut d'Oncologia (VHIO)) ; Roselló, S (Universidad de Valencia. Biomedical Research Institute (INCLIVA)) ; Van Cutsem, E (University Hospitals Gasthuisberg and KU Leuven) ; Tejpar, S (University Hospitals Gasthuisberg and KU Leuven) ; Prenen, H (University Hospitals Gasthuisberg and KU Leuven) ; Martinelli, E (Second University of Naples. Department of Experimental and Clinical Medicine) ; Troiani, T (Second University of Naples. Department of Experimental and Clinical Medicine) ; Laffranchi, B (Merck Serono SA) ; Jego, V (Merck Serono SA) ; von Richter, O (Merck KGaA) ; Ciardiello, F (Second University of Naples. Department of Experimental and Clinical Medicine) ; Universitat Autònoma de Barcelona
The mitogen-activated protein kinase (MAPK) pathway has been implicated in the molecular pathogenesis of human cancers, including metastatic colorectal cancer (mCRC). This provides a rationale for the development of MAPK-targeted agents such as pimasertib. [...]
2015 - 10.1038/bjc.2015.144
British Journal of Cancer, Vol. 112 (June 2015) , p. 1874-1881  

See also: similar author names
1 Ciardiello, F.
2 Ciardiello, Fortunato
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