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Articles, 2 records found
Articles 2 records found  
1.
12 p, 3.0 MB Double deficiency of Trex2 and DNase1L2 nucleases leads to accumulation of DNA in lingual cornifying keratinocytes without activating inflammatory responses / Manils, Joan (Universitat de Barcelona. Departament de Patologia i Terapèutica Experimental) ; Fischer, Heinz (Medical University of Vienna. Department of Dermatology) ; Climent, Joan (Universitat de Barcelona. Departament de Patologia i Terapèutica Experimental) ; Casas, Eduard (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; García-Martínez, Celia (Universitat de Barcelona. Departament de Patologia i Terapèutica Experimental) ; Bas, Jordi (Universitat de Barcelona. Departament de Patologia i Terapèutica Experimental) ; Sukseree, Supawadee (Medical University of Vienna. Department of Dermatology) ; Vavouri, Tanya (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Ciruela, Francisco (Universitat de Barcelona. Departament de Patologia i Terapèutica Experimental) ; de Anta, Josep Maria (Universitat de Barcelona. Departament de Patologia i Terapèutica Experimental) ; Tschachler, Erwin (Medical University of Vienna. Department of Dermatology) ; Eckhart, Leopold (Medical University of Vienna. Department of Dermatology) ; Soler, Concepció (Universitat de Barcelona. Departament de Patologia i Terapèutica Experimental) ; Universitat Autònoma de Barcelona
The cornification of keratinocytes on the surface of skin and oral epithelia is associated with the degradation of nuclear DNA. The endonuclease DNase1L2 and the exonuclease Trex2 are expressed specifically in cornifying keratinocytes. [...]
2017 - 10.1038/s41598-017-12308-4
Scientifics reports, Vol. 7 (september 2017) , p. 1-12  
2.
11 p, 2.3 MB Illuminating phenylazopyridines to photoswitch metabotropic glutamate receptors : from the flask to the animals / Gómez-Santacana, Xavier (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Pittolo, Silvia (Institut de Bioenginyeria de Catalunya) ; Rovira, Xavier (Université de Montpellier. Institute of Functional Genomics) ; Lopez, Marc (Universitat de Barcelona. Unitat de Farmacologia) ; Zussy, Charleine (Université de Montpellier. Institute of Functional Genomics) ; Dalton, James A.R. (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Faucherre, Adèle (Université de Montpellier. Institute of Functional Genomics) ; Jopling, Chris (Université de Montpellier. Institute of Functional Genomics) ; Pin, Jean-Philippe (Université de Montpellier. Institute of Functional Genomics) ; Ciruela, Francisco (Universitat de Barcelona. Unitat de Farmacologia) ; Goudet, Cyril (Université de Montpellier. Institute of Functional Genomics) ; Giraldo, Jesús (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Gorostiza, Pau (Institut de Bioenginyeria de Catalunya) ; Llebaria, Amadeu (Instituto de Química Avanzada de Cataluña)
Phenylazopyridines are photoisomerizable compounds with high potential to control biological functions with light. We have obtained a series of phenylazopyridines with light dependent activity as negative allosteric modulators (NAM) of metabotropic glutamate receptor subtype 5 (mGlu). [...]
2017 - 10.1021/acscentsci.6b00353
ACS Central Science, Vol. 3, issue 1 (Jan. 2017) , p. 81-91  

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3 Ciruela, Francisco
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