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19 p, 9.2 MB |
Genomic analysis of Mycobacterium brumae sustains its nonpathogenic and immunogenic phenotype
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Renau-Mínguez, Chantal (University of Valencia-FISABIO Joint Unit) ;
Herrero Abadía, Paula (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Ruiz-Rodriguez, Paula (University of Valencia-FISABIO Joint Unit) ;
Sentandreu, Vicente (University of Valencia) ;
Torrents, Eduard (Universitat de Barcelona) ;
Chiner-Oms, Álvaro (Instituto de Biomedicina de Valencia (IBV-CSIC)) ;
Torres-Puente, Manuela (Instituto de Biomedicina de Valencia (IBV-CSIC)) ;
Comas, I (Instituto de Biomedicina de Valencia (IBV-CSIC)) ;
Julián Gómez, Esther (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Coscolla, Mireia (University of Valencia-FISABIO Joint Unit)
Mycobacterium brumae is a rapid-growing, non-pathogenic Mycobacterium species, originally isolated from environmental and human samples in Barcelona, Spain. Mycobacterium brumae is not pathogenic and it's in vitro phenotype and immunogenic properties have been well characterized. [...]
2023 -  10.3389/fmicb.2022.982679
Frontiers in microbiology, Vol. 13 (January 2023) , art. 982679
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2.
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11 p, 3.1 MB |
Genomic analyses of Mycobacterium tuberculosis from human lung resections reveal a high frequency of polyclonal infections
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Moreno-Molina, Miguel (Instituto de Biomedicina de Valencia (IBV-CSIC)) ;
Shubladze, Natalia (National Center for Tuberculosis and Lung Diseases of Georgia) ;
Khurtsilava, Iza (National Center for Tuberculosis and Lung Diseases of Georgia) ;
Avaliani, Zaza (National Center for Tuberculosis and Lung Diseases of Georgia) ;
Bablishvili, Nino (National Center for Tuberculosis and Lung Diseases of Georgia) ;
Torres-Puente, Manuela (Instituto de Biomedicina de Valencia (IBV-CSIC)) ;
Villamayor, Luis (FISABIO Public Health) ;
Gabrielian, Andrei (National Institutes of Health. Department of Health and Human Services (Estats Units d'Amèrica)) ;
Rosenthal, Alex (National Institutes of Health. Department of Health and Human Services (Estats Units d'Amèrica)) ;
Vilaplana, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Gagneux, Sebastien (University of Basel) ;
Kempker, Russell R. (Emory University School of Medicine. Department of Medicine) ;
Vashakidze, Sergo (National Center for Tuberculosis and Lung Diseases of Georgia) ;
Comas, I (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Universitat Autònoma de Barcelona
Polyclonal infections occur when at least two unrelated strains of the same pathogen are detected in an individual. This has been linked to worse clinical outcomes in tuberculosis, as undetected strains with different antibiotic resistance profiles can lead to treatment failure. [...]
2021 - 10.1038/s41467-021-22705-z
Nature communications, Vol. 12 (may 2021)
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3.
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1.0 MB |
Mycobacterium tuberculosis Acquires Limited Genetic Diversity in Prolonged Infections, Reactivations and Transmissions Involving Multiple Hosts
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Herranz, Marta (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Pole, Ilva (Latvian Biomedical Research and Study Centre) ;
Ozere, Iveta (Department of Infectology and Dermatology, Riga Stradinš University) ;
Chiner-Oms, Álvaro (Unidad Mixta Genómica y Salud, Centro Superior de Investigación en Salud Pública (FISABIO)-Universitat de València) ;
Martínez-Lirola, Miguel (Complejo Hospitalario Torrecárdenas (Almeria)) ;
Pérez-García, Felipe (Hospital General Universitario Gregorio Marañón) ;
Gijón, Paloma (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Serrano, María Jesús Ruiz (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Romero, Laura Clotet (Agència de Salut Pública de Catalunya) ;
Cuevas, Oscar (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Comas, I (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Bouza, Emilio (Universidad Complutense de Madrid) ;
Pérez-Lago, Laura (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
García-de-Viedma, Darío (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Universitat Autònoma de Barcelona
Background: Mycobacterium tuberculosis (MTB) has limited ability to acquire variability. Analysis of its microevolution might help us to evaluate the pathways followed to acquire greater infective success. [...]
2018 - 10.3389/fmicb.2017.02661
Frontiers in microbiology, Vol. 8 (january 2018)
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4.
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3 p, 80.3 KB |
Serum Luteinizing Hormone Testing Can Identify Optimal Medical Castration
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Morote Robles, Juan (Universitat Autònoma de Barcelona) ;
Comas Reixach, Imma (Hospital Universitari Vall d'Hebron) ;
Ferrer Costa, Roser (Hospital Universitari Vall d'Hebron) ;
Regis, Lucas (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Celma, Ana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Santamaría, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Planas, Jacques (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Trilla Herrera, Enrique (Universitat Autònoma de Barcelona)
2020 - 10.1016/j.euros.2020.06.002
European Urology Open Science, Vol. 19 (july 2020) , p. 24-26
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5.
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2 p, 177.4 KB |
Draft Genome Sequence of Mycobacterium brumae ATCC 51384
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D'Auria, Giuseppe (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Torrents, Eduard (Institut de Bioenginyeria de Catalunya) ;
Luquín Fernández, Marina (Marina) (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Comas, I (Instituto de Biomedicina de Valencia (IBV-CSIC)) ;
Julián Gómez, Esther (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Here, we report the draft genome sequence of Mycobacterium brumae type strain ATCC 51384. This is the first draft genome sequence of M. brumae, a nonpathogenic, rapidly growing, nonchromogenic mycobacterium, with immunotherapeutic capacities.
2016 - 10.1128/genomeA.00237-16
Genome announcements, Vol. 4, Issue 2 (April 2016) , Art. e00237-16
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11 p, 2.6 MB |
Biomarkers and clinical scores to aid the identification of disease severity and intensive care requirement following activation of an in-hospital sepsis code
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Baldira Martínez de Irujo, Jaume (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Ruiz-Rodríguez, Juan Carlos (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Wilson, Darius Cameron (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ruiz-Sanmartin, Adolf (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Cortes, Alejandro (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Chiscano-Camón, Luis (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ferrer Costa, Roser (Hospital Universitari Vall d'Hebron) ;
Comas Reixach, Imma (Hospital Universitari Vall d'Hebron) ;
Larrosa, María Nieves (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Fàbrega-Santamaria, Anna (Hospital Universitari Vall d'Hebron) ;
González-López, Juanjo 1975- (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Ferrer, Ricard (Hospital Universitari Vall d'Hebron. Institut de Recerca)
Few validated biomarker or clinical score combinations exist which can discriminate between cases of infection and other non-infectious conditions following activation of an in-hospital sepsis code, as well as provide an accurate severity assessment of the corresponding host response. [...]
2020 - 10.1186/s13613-020-0625-5
Annals of Intensive Care, Vol. 10 (January 2020) , art. 7
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7.
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18 p, 5.0 MB |
Influence of Gut Microbiota on Progression to Tuberculosis Generated by High Fat Diet-Induced Obesity in C3HeB/FeJ Mice
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Arias, Lilibeth (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Goig, Galo A. (Instituto de Biomedicina de Valencia (IBV-CSIC)) ;
Cardona, Paula (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Torres-Puente, Manuela (Instituto de Biomedicina de Valencia (IBV-CSIC)) ;
Díaz, Jorge (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Rosales, Yaiza (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
García, Eric (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Tapia, Gustavo (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Comas, I (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Vilaplana, Cristina (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Cardona, Pere-Joan (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
The administration of a high fat content diet is an accelerating factor for metabolic syndrome, impaired glucose tolerance, and early type 2 diabetes. The present study aims to assess the impact of a high fat diet on tuberculosis progression and microbiota composition in an experimental animal model using a C3HeB/FeJ mouse strain submitted to single or multiple consecutive aerosol infections. [...]
2019 - 10.3389/fimmu.2019.02464
Frontiers in immunology, Vol. 10 (October 2019) , art. 2464
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2 p, 156.4 KB |
Draft genome sequences of Mycobacterium setense type strain DSM-45070 and the nonpathogenic strain Manresensis, isolated from the bank of the Cardener river in Manresa, Catalonia, Spain
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Rech, Gabriel (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ;
Vilaplana i Massaguer, Cristina (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Velasco, Juan (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ;
Pluvinet, Raquel (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ;
Santín, Sheila (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ;
Prat i Aymerich, Cristina, dir. (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Julián Gómez, Esther (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Alcaide, Fernando (Universitat de Barcelona. Departament de Patologia i Terapèutica Experimental) ;
Comas, I (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Sumoy, Lauro (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ;
Cardona, Pere-Joan (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
We present here the draft genome sequences of two Mycobacterium setense strains. One of them corresponds to the M. setense type strain DSM-45070, originally isolated from a patient with a posttraumatic chronic skin abscess. [...]
2015 - 10.1128/genomeA.01485-14
Genome announcements, Vol. 3, Issue 1 (Jan-Feb. 2015) , p. e01485-14
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