Results overview: Found 4 records in 0.02 seconds.
Articles, 4 records found
Articles 4 records found  
1.
13 p, 2.8 MB Global proteomic and methylome analysis in human induced pluripotent stem cells reveals overexpression of a human TLR3 affecting proper innate immune response signaling / Requena, Jordi (Universitat de Barcelona. Departament de Biomedicina) ; Álvarez Palomo, Ana Belén (Universitat de Barcelona. Departament de Biomedicina) ; Codina Pascual, Montserrat (Universitat de Barcelona. Departament de Biomedicina) ; Delgado Morales, Raul (Institut d'Investigació Biomèdica de Bellvitge) ; Moran, Sebastian (Institut d'Investigació Biomèdica de Bellvitge) ; Esteller, Manel (Institut d'Investigació Biomèdica de Bellvitge) ; Sal, Martí (Universitat de Barcelona. Departament de Biomedicina) ; Juan, Manel (Universitat de Barcelona. Hospital Clínic. Servei d'Immunologia) ; Boronat Barado, Anna (Universitat de Barcelona. Hospital Clínic. Servei d'Immunologia) ; Consiglio, Antonella (Institut d'Investigació Biomèdica de Bellvitge) ; Bogle, Orleigh Addeleccia (Universitat de Barcelona. Departament de Biomedicina) ; Wolvetang, Ernst (University of Queensland. Australian Institute for Bioengineering and Nanotechnology) ; Ovchinnikov, Dmitry (University of Queensland. Australian Institute for Bioengineering and Nanotechnology) ; Álvarez Angulo, Iñaki (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Jaraquemada, Dolores (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Mezquita Pla, Jovita (Universitat de Barcelona. Departament de Biomedicina) ; Oliva, R. (Universitat de Barcelona. Departament de Biomedicina) ; Edel, Michael J. (Universitat de Barcelona. Departament de Biomedicina)
When considering the clinical applications of autologous cell replacement therapy of human induced pluripotent stem cells (iPSC)-derived cells, there is a clear need to better understand what the immune response will be before we embark on extensive clinical trials to treat or model human disease. [...]
2019 - 10.1002/stem.2966
Stem Cells, Vol. 37, issue 4 (April 2019) , p. 476-488  
2.
20 p, 8.2 MB The small GTPase RAC1/CED-10 is essential in maintaining dopaminergic neuron function and survival against α-synuclein-induced toxicity / Kim, Hanna (University of Alabama. Department of Biological Sciences) ; Calatayud, Carles (Institut d'Investigació Biomèdica de Bellvitge) ; Guha, Sanjib (Buck Institute for Age Research) ; Fernández Carasa, Irene (Institut de Biomedicina de la Universitat de Barcelona) ; Berkowitz, Laura (University of Alabama. Department of Biological Sciences) ; Carballo Carbajal, Iria (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Ezquerra, Mario (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Fernández Santiago, Rubén (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Kapahi, Pankaj (Buck Institute for Age Research) ; Raya, Ángel (Institució Catalana de Recerca i Estudis Avançats) ; Miranda Vizuete, Antonio (Instituto de Biomedicina de Sevilla) ; Lizcano de Vega, José Miguel (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Vila Bover, Miquel (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Caldwell, Kim A. (University of Alabama. Department of Biological Sciences) ; Caldwell, Guy A. (University of Alabama. Department of Biological Sciences) ; Consiglio, Antonella (Università degli Studi di Brescia. Dipartimento di Medicina Molecolare e Traslazionale) ; Dalfo Capella, Esther (Universitat Autònoma de Barcelona. Departament de Biologia i Bioquímica Molecular)
Parkinson's disease is associated with intracellular α-synuclein accumulation and ventral midbrain dopaminergic neuronal death in the Substantia Nigra of brain patients. The Rho GTPase pathway, mainly linking surface receptors to the organization of the actin and microtubule cytoskeletons, has been suggested to participate to Parkinson's disease pathogenesis. [...]
2018 - 10.1007/s12035-018-0881-7
Molecular neurobiology, Vol. 55, issue 9 (Sep. 2018) , p. 7533-7552  
3.
18 p, 2.2 MB Aberrant epigenome in -derived dopaminergic neurons from Parkinson's disease patients / Fernández-Santiago, Rubén (Universitat de Barcelona) ; Carballo-Carbajal, Iria (Vall d'Hebron Institut de Recerca (VHIR)) ; Castellano, Giancarlo (Universitat de Barcelona. Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Torrent, Roger (Universitat de Barcelona. Institut de Biomedicina (IBUB)) ; Richaud, Yvonne (Biomaterials and Nanomedicine (CIBER-BBN). Centre for Networked Biomedical Research on Bioengineering) ; Sánchez-Danés, Adriana (Universitat de Barcelona. Institut de Biomedicina (IBUB)) ; Vilarrasa-Blasi, Roser (Universitat de Barcelona. Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Sánchez-Pla, Alex (Vall d'Hebron Institut de Recerca (VHIR)) ; Mosquera, José Luis (Universitat de Barcelona) ; Soriano, Jordi (Universitat de Barcelona) ; López-Barneo, José (Universidad de Sevilla. Hospital Universitario Virgen del Rocío.) ; Canals, Josep M (Universitat de Barcelona. Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Alberch i Vié, Jordi (Universitat de Barcelona. Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Raya, Ángel (Institució Catalana de Recerca i Estudis Avançats (ICREA)) ; Vila Bover, Miquel (Vall d'Hebron Institut de Recerca (VHIR)) ; Consiglio, Antonella (University of Brescia and National Institute of Neuroscience) ; Martín-Subero, José I (Universitat de Barcelona. Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Ezquerra, Mario (Universitat de Barcelona. Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Tolosa, Eduardo (Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED)) ; Universitat Autònoma de Barcelona
The epigenomic landscape of Parkinson's disease () remains unknown. We performed a genomewide methylation and a transcriptome studies in induced pluripotent stem cell ()-derived dopaminergic neurons (n) generated by cell reprogramming of somatic skin cells from patients with monogenic 2-associated (L2) or sporadic (), and healthy subjects. [...]
2015 - 10.15252/emmm.201505439
EMBO Molecular Medicine, Vol. 7, Núm. 12 (October 2015) , p. 1529-1546  
4.
39 p, 2.8 MB Disease-corrected haematopoietic progenitors from Fanconi anemia induced pluripotent stem cells / Raya, Ángel (Institució Catalana de Recerca i Estudis Avançats (ICREA)) ; Rodríguez-Pizà, Ignasi (Center for Regenerative Medicine in Barcelona) ; Guenechea, Guillermo (Networking Center of Biomedical Research in Rare Diseases (CIBERER)) ; Vassena, Rita (Center for Regenerative Medicine in Barcelona) ; Navarro, Susana (Networking Center of Biomedical Research in Rare Diseases (CIBERER)) ; Barrero, María José (Center for Regenerative Medicine in Barcelona) ; Consiglio, Antonella (University of Brescia. Department of Biomedical Science and Biotechnology) ; Castellà, Maria (Universitat Autònoma de Barcelona. Department of Genetics and Microbiology) ; Río, Paula (Networking Center of Biomedical Research in Rare Diseases (CIBERER)) ; Sleep, Eduard (Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN)) ; González, Federico (Center for Regenerative Medicine in Barcelona) ; Tiscornia, Gustavo (Center for Regenerative Medicine in Barcelona) ; Garreta, Elena (Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN)) ; Aasen, Trond (Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN)) ; Veiga, Anna (Center for Regenerative Medicine in Barcelona) ; Verma, Inder M. (Laboratory of Genetics, Salk Institute for Biological Studies) ; Surrallés i Calonge, Jordi (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Bueren, Juan (Hematopoiesis and Gene Therapy Division, Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT)) ; Izpisúa Belmonte, Juan Carlos (Gene Expression Laboratory, Salk Institute for Biological Studies)
The generation of induced pluripotent stem (iPS) cells by ectopic expression of a defined set of factors1-5 has enabled the derivation of patient-specific pluripotent cells and provided valuable experimental platforms to model human disease6-8. [...]
2009 - 10.1038/nature08129
Nature, Núm. 460 (05 2009) , p. 53-59  

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