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8 p, 424.3 KB Relationship Between Bone Mineral Density T -Score and Nonvertebral Fracture Risk Over 10 Years of Denosumab Treatment / Ferrari, Serge (Geneva University Hospitals (Suïssa)) ; Libanati, Cesar (UCB Pharma) ; Fang Lin, Celia Jow (Amgen Inc) ; Brown, Jacques P. (Laval University and CHU de Québec Research Centre) ; Cosman, Felicia (Columbia University) ; Czerwiński, Edward (Krakow Medical Center) ; de Gregόrio, L. H. (Center for Clinical and Basic Research - Brasil) ; Malouf Sierra, Jorge 1971- (Universitat Autònoma de Barcelona) ; Reginster, Jean-Yves (University of Liège) ; Wang, Andrea T. (Amgen Inc) ; Wagman, Rachel B. (Amgen Inc) ; Lewiecki, E. Michael (New Mexico Clinical Research & Osteoporosis Center)
Although treat-to-target strategies are being discussed in osteoporosis, there is little evidence of what the target should be to reduce fracture risk maximally. We investigated the relationship between total hip BMD T -score and the incidence of nonvertebral fracture in women who received up to 10 years of continued denosumab therapy in the FREEDOM (3 years) study and its long-term Extension (up to 7 years) study. [...]
2019 - 10.1002/jbmr.3722
Journal of Bone and Mineral Research, Vol. 34 (may 2019) , p. 1033-1040  

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1 Cosman, Felicia
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