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13 p, 1.5 MB Medical vulnerability of individuals with Down syndrome to severe COVID-19-data from the Trisomy 21 Research Society and the UK ISARIC4C survey / Hüls, Anke (Department of Epidemiology and Gangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA) ; Costa, Alberto C. S. (Departments of Pediatrics and of Psychiatry, School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA) ; Dierssen, Mara (Centro de Investigación Biomédica en Red de Enfermedades Raras) ; Baksh, R. Asaad (The London Down Syndrome (LonDownS) Consortium, London, United Kingdom) ; Bargagna, Stefania (Fondazione Stella Maris IRCCS, Pisa, Italy) ; Baumer, Nicole (Harvard Medical School) ; Brandão, Ana Claudia (Hospital Israelita Albert Einstein (Sao Paolo, Brasil)) ; Carfi, Angelo (Policlinico Universitario Agostino Gemelli IRCCS (Roma, Itàlia)) ; Carmona Iragui, María (Institut d'Investigació Biomèdica Sant Pau) ; Chicoine, Brian (Advocate Medical Group Adult Down Syndrome Center, Park Ridge, IL, USA) ; Ghosh, Sujay (Cytogenetics and Genomics Reserach Unit. Department of Zoology, University of Calcutta.Kolkata. West Bengal, India) ; Lakhanpaul, Monica (Whttington NHS Trust, London, United Kingdom; Down Syndrome Medical Interest Group, London, United Kingdom) ; Manso, Coral (CM: DOWN ESPAÑA, Madrid, Spain) ; Mayer, Miguel-Angel (Institut Hospital del Mar d'Investigacions Mèdiques) ; Ortega, Maria del Carmen (Hospital Universitario 12 de Octubre (Madrid)) ; de Asua, Diego Real (Instituto de Investigación Hospital Universitario de la Princesa) ; Rebillat, Anne-Sophie (Institut Jérôme Lejeune, Paris, France) ; Russell, Lauren Ashley (Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA) ; Sgandurra, Giuseppina (Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy) ; Valentini, Diletta (Bambino Gesù Children's Hospital) ; Sherman, Stephanie L. (Department of Human Genetics, School of Medicine, Emory University, Atlanta, Georgia, USA) ; Strydom, Andre (South London and the Maudsley NHS Foundation Trust) ; Universitat Autònoma de Barcelona
Health conditions, immune dysfunction, and premature aging associated with trisomy 21 (Down syndrome, DS) may impact the clinical course of COVID-19. The T21RS COVID-19 Initiative launched an international survey for clinicians or caregivers on patients with COVID-19 and DS. [...]
2021 - 10.1016/j.eclinm.2021.100769
EClinicalMedicine, february 2021  

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