Resultats globals: 7 registres trobats en 0.02 segons.
Articles, 5 registres trobats
Documents de recerca, 2 registres trobats
Articles 5 registres trobats  
1.
15 p, 7.0 MB Inactivation of the dimeric Rap anti-repressor of the conjugation operon is mediated by peptide-induced tetramerization / Crespo, Isidro (ALBA Laboratori de Llum de Sincrotró) ; Bernardo, Nerea (ALBA Laboratori de Llum de Sincrotró) ; Miguel-Arribas, Andrés (Centro de Biología Molecular 'Severo Ochoa') ; Singh, Praveen K. (Centro de Biología Molecular 'Severo Ochoa') ; Luque-Ortega, Juan R. (Centro de Investigaciones Biológicas Margarita Salas) ; Alfonso, Carlos (Centro de Investigaciones Biológicas Margarita Salas) ; Malfois, Marc (ALBA Laboratori de Llum de Sincrotró) ; Meijer, Wilfried J. J. (Centro de Biología Molecular 'Severo Ochoa') ; Boer, Roeland (ALBA Laboratori de Llum de Sincrotró)
Quorum sensing allows bacterial cells to communicate through the release of soluble signaling molecules into the surrounding medium. It plays a pivotal role in controlling bacterial conjugation in Gram-positive cells, a process that has tremendous impact on health. [...]
2020 - 10.1093/nar/gkaa540
Nucleic acids research, Vol. 48, issue 14 (Aug. 2020) , p. 8113-8127  
2.
13 p, 2.9 MB Efficacy of aldose reductase inhibitors is affected by oxidative stress induced under X-ray irradiation / Castellví Toledo, Albert (ALBA Laboratori de Llum de Sincrotró) ; Crespo, Isidro (ALBA Laboratori de Llum de Sincrotró) ; Crosas, Eva (ALBA Laboratori de Llum de Sincrotró) ; Cámara Artigas, Ana (Universidad de Almería) ; Gavira, José A. (Universidad de Granada) ; García Aranda, Miguel Ángel (ALBA Laboratori de Llum de Sincrotró) ; Parés i Casasampera, Xavier (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Farrés i Vicén, Jaume (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Juanhuix, Judith (ALBA Laboratori de Llum de Sincrotró)
Human aldose reductase (hAR, AKR1B1) has been explored as drug target since the 1980s for its implication in diabetic complications. An activated form of hAR was found in cells from diabetic patients, showing a reduced sensitivity to inhibitors in clinical trials, which may prevent its pharmacological use. [...]
2019 - 10.1038/s41598-019-39722-0
Scientific reports (Nature Publishing Group), Vol. 9 (February 2019) , art. 3177  
3.
17 p, 5.8 MB Novel regulatory mechanism of establishment genes of conjugative plasmids / Val-Calvo, Jorge (Centro de Biología Molecular Severo Ochoa (CSIC-UAM)) ; Luque-Ortega, Juan Roman (Centro de Investigaciones Biológicas) ; Crespo, Isidro (ALBA Laboratori de Llum de Sincrotró) ; Miguel Arribas, Andrés (Centro de Biología Molecular "Severo Ochoa" (CSIC-UAM)) ; Abia, David (Centro de Biología Molecular "Severo Ochoa" (CSIC-UAM)) ; Sánchez-Hevia, Dione L. (Centro de Biología Molecular "Severo Ochoa" (CSIC-UAM)) ; Serrano, Ester (Centro de Biología Molecular "Severo Ochoa" (CSIC-UAM)) ; Gago-Córdoba, César (Centro de Biología Molecular "Severo Ochoa" (CSIC-UAM)) ; Ares, Saúl (Universidad Carlos III de Madrid) ; Alfonso, Carlos (Centro de Investigaciones Biológicas (Madrid)) ; Rojo, Fernando (Centro Nacional de Biotecnología (CSIC)) ; Wu, Ling J. (Newcastle University) ; Boer, Roeland (ALBA Laboratori de Llum de Sincrotró) ; Meijer, Wilfried J. J. (Centro de Biología Molecular "Severo Ochoa" (CSIC-UAM))
The principal route for dissemination of antibiotic resistance genes is conjugation by which a conjugative DNA element is transferred from a donor to a recipient cell. Conjugative elements contain genes that are important for their establishment in the new host, for instance by counteracting the host defense mechanisms acting against incoming foreign DNA. [...]
2018 - 10.1093/nar/gky996
Nucleic acids research, Vol. 46, Issue 22 (December 2018) , p. 11910-11926  
4.
23 p, 2.2 MB Discovery of a new family of relaxases in Firmicutes bacteria / Gayetri Ramachandran, Andrés (Centro de Biología Molecular Severo Ochoa) ; Miguel Arribas, Andrés (Centro de Biología Molecular Severo Ochoa) ; Abia, David (Centro de Biología Molecular Severo Ochoa) ; Singh, Praveen K. (Centro de Biología Molecular Severo Ochoa) ; Crespo, Isidro (ALBA Laboratori de Llum de Sincrotró) ; Gago-Córdoba, César (Centro de Biología Molecular Severo Ochoa) ; Hao, Jian An (Centro de Biología Molecular Severo Ochoa) ; Luque-Ortega, Juan Roman (Centro de Investigaciones Biológicas (Madrid)) ; Alfonso, Carlos (Centro de Investigaciones Biológicas (Madrid)) ; Wu, Ling J. (Newcastle University. Institute for Cell and Molecular Biosciences. Centre for Bacterial Cell Biology) ; Boer, Roeland (ALBA Laboratori de Llum de Sincrotró) ; Meijer, Wilfried J. J. (Centro de Biología Molecular Severo Ochoa)
Antibiotic resistance is a serious global problem. Antibiotic resistance genes (ARG), which are widespread in environmental bacteria, can be transferred to pathogenic bacteria via horizontal gene transfer (HGT). [...]
2017 - 10.1371/journal.pgen.1006586
PLoS Genetics, Vol. 13, issue 2 (Feb. 2017) , e1006586  
5.
19 p, 2.5 MB Substrate Specificity, Inhibitor Selectivity and Structure-Function Relationships of Aldo-Keto Reductase 1B15 : a Novel Human Retinaldehyde Reductase / Giménez Dejoz, Joan (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Kolář, Michal H. (Academy of Sciences of the Czech Republic. Institute of Organic Chemistry and Biochemistry) ; Ruiz, Francesc X. (Centre de Biologie Intégrative (Illkirch-Graffenstaden, França)) ; Crespo, Isidro (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Cousido-Siah, Alexandra (Centre de Biologie Intégrative (Illkirch-Graffenstaden, França)) ; Podjarny, Alberto (Centre de Biologie Intégrative (Illkirch-Graffenstaden, França)) ; Barski, Oleg A. (University of Louisville. School of Medicine) ; Fanfrlík, Jindřich (Academy of Sciences of the Czech Republic. Institute of Organic Chemistry and Biochemistry) ; Parés i Casasampera, Xavier (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Farrés i Vicén, Jaume (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Porté Orduna, Sergio (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Human aldo-keto reductase 1B15 (AKR1B15) is a newly discovered enzyme which shares 92% amino acid sequence identity with AKR1B10. While AKR1B10 is a well characterized enzyme with high retinaldehyde reductase activity, involved in the development of several cancer types, the enzymatic activity and physiological role of AKR1B15 are still poorly known. [...]
2015 - 10.1371/journal.pone.0134506
PloS one, Vol. 10 Núm. 7 (July 2015) , p. e0134506  

Documents de recerca 2 registres trobats  
1.
Auxin Response Factors : integrating auxin signalling with DNA recognition and epigenetics / Crespo García, Isidro ; Boer, Roeland D., 1972-, dir. ; Weijers, Dolf, dir.
Les auxines són les principals fitohormones que governen el creixement i desenvolupament de les plantes, principalment a través de la via nuclear de l'auxina, NAP. Els efectors finals en NAP són els factors de resposta d'auxina (ARF). [...]
Las auxinas son las principales fitohormonas que gobiernan el crecimiento y desarrollo de las plantas, principalmente a través de la vía de las auxinas nucleares, NAP. Los efectores finales en NAP son los factores de respuesta de auxina (ARF). [...]
Auxins are the main phytohormones governing plant growth and development mainly through the Nuclear Auxin Pathway, NAP. The final effectors on NAP are the Auxin Response Factors (ARFs). ARFs has been linked to auxin and gene expression for decades, but the recent crystallographic structures of the DNA Binding Domain (ARF-DBD) of two divergent Arabidopsis thaliana ARFs revealed an exceptionally high conservation of the DNA contact points, so this point was unlikely to determine specificity of gene selection. [...]
Universitat Autònoma de Barcelona. Programa de Doctorat en Bioquímica, Biologia Molecular i Biomedicina.

2021  
2.
1 p, 1.1 MB Proteïnes cel·lulars i d'unió retinoides : estructura, funció al metabolisme i a l'acció dels retinoides / Crespo, Isidro ; Parés i Casasampera, Xavier, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2013
Grau en Bioquímica [814]  

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