Resultats globals: 5 registres trobats en 0.01 segons.
Articles, 5 registres trobats
Articles 5 registres trobats  
1.
9 p, 1.7 MB Switching From a Protease Inhibitor–based Regimen to a Dolutegravir-based Regimen : A Randomized Clinical Trial to Determine the Effect on Peripheral Blood and Ileum Biopsies From Antiretroviral Therapy–suppressed Human Immunodeficiency Virus–infected Individuals / Morón-López, Sara (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Navarro, Jordi (Institut de Recerca Vall d'Hebron) ; Jimenez, Montse (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Rutsaert, Sofie (Human Immunodeficiency Virus Cure Research Center, Department of Internal Medicine, Faculty of Medicine and Health Sciences, Ghent University and Ghent University Hospital) ; Urrea, Víctor (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Puertas, Maria C (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Torrella, Ariadna (Hospital Universitari Vall d'Hebron) ; De Clercq, Laura (Human Immunodeficiency Virus Cure Research Center, Department of Internal Medicine, Faculty of Medicine and Health Sciences, Ghent University and Ghent University Hospital) ; Ribas, Bibiana Planas (,Hospital Universitari Vall d'Hebron) ; Gálvez, Cristina (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Salgado, Maria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Vandekerckhove, Linos (Human Immunodeficiency Virus Cure Research Center, Department of Internal Medicine, Faculty of Medicine and Health Sciences, Ghent University and Ghent University Hospital) ; Blanco, Julià (University of Vic–Central University of Catalonia) ; Crespo, Manel (Infectious Diseases Unit, Internal Medicine Department, Complexo Hospitalario Universitario de Vigo, Instituto de Investigación Sanitaria Galicia Sur) ; Martinez-Picado, Javier (Catalan Institution for Research and Advanced Studies) ; Universitat Autònoma de Barcelona
Optimization of combination antiretroviral therapy (cART) can impact the human immunodeficiency virus (HIV) reservoir. We evaluated the effect on the HIV reservoir in peripheral blood and ileum biopsies in patients switching from boosted protease inhibitor (PI/r)–based therapy to dolutegravir (DTG)–based therapy. [...]
2018 - 10.1093/cid/ciy1095
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America, Vol. 69 (december 2018) , p. 1320-1328  
2.
15 p, 676.0 KB Mechanisms of abrupt loss of virus control in a cohort of previous HIV controllers / Rosás Umbert, Miriam (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Llano, Anuska (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Bellido, Rocío (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Olvera, Alex (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Ruiz-Riol, Marta (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Rocafort, Muntsa (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Fernández, Marco A. (Institut Germans Trias i Pujol) ; Cobarsi, Patricia (Institut Germans Trias i Pujol) ; Crespo, Manel (Complexo Hospitalario Universitario de Vigo) ; Dorrell, Lucy (Nuffield Department of Medicine, University of Oxford,) ; del Romero, Jorge (Centro Sanitario Sandoval, Madrid) ; Alcami, José (Instituto de Salud Carlos III, Madrid) ; Paredes, Roger (Universitat Autònoma de Barcelona. Departament de Medicina) ; Brander, Christian (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Mothe, Beatriz (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa)
A few individuals can control HIV infection without the need for antiretroviral treatment and are referred to as HIV controllers. We have studied HIV controllers who suddenly lose this ability and present with high in vivo viral replication and decays in their CD4 + T-cell counts to identify potential immune and virological factors that were responsible for initial virus control. [...]
2019 - 10.1128/JVI.01436-18
Journal of Virology, Vol. 93 (february 2019)  
3.
10 p, 2.1 MB Sensitive quantification of the HIV-1 reservoir in gut-associated lymphoid tissue / Morón López, Sara (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Puertas, Maria C. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Gálvez, Cristina (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Navarro, Jordi (Hospital Universitari Vall d'Hebron) ; Carrasco, Anna (Hospital Universitari Mutua de Terrassa) ; Esteve, Maria (Hospital Universitari Mutua de Terrassa) ; Manyè, Josep (Institut Germans Trias i Pujol. CIBEREHD) ; Crespo, Manel (Hospital Universitari Vall d'Hebron) ; Salgado, Maria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Martinez Picado, Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa)
Background. The implementation of successful strategies to achieve an HIV cure has become a priority in HIV research. However, the current location and size of HIV reservoirs is still unknown since there are limited tools to evaluate HIV latency in viral sanctuaries such as gut-associated lymphoid tissue (GALT). [...]
2017
Plos one, Vol. 12 Núm. 4 (2017) , p. 1-10  
4.
12 p, 2.8 MB Gut microbiota linked to sexual preference and HIV infection / Noguera-Julian, Marc (Institut Germans Trias i Pujol. IrsiCaixa) ; Rocafort, Muntsa (Institut Germans Trias i Pujol. IrsiCaixa) ; Guillén, Yolanda (Institut Germans Trias i Pujol. IrsiCaixa) ; Rivera, Javier (Institut Germans Trias i Pujol. IrsiCaixa) ; Casadellà, Maria (Institut Germans Trias i Pujol. IrsiCaixa) ; Nowak, Piotr (Karolinska Universitetssjukhuset) ; Hildebrand, Falk (European Molecular Biology Laboratory) ; Zeller, Georg (European Molecular Biology Laboratory) ; Parera, Mariona (Institut Germans Trias i Pujol. IrsiCaixa) ; Bellido, Rocío (Institut Germans Trias i Pujol. IrsiCaixa) ; Rodríguez, Cristina (Institut Germans Trias i Pujol. IrsiCaixa) ; Carrillo, Jorge (Institut Germans Trias i Pujol. IrsiCaixa) ; Mothe, Beatriz (Institut Germans Trias i Pujol. IrsiCaixa) ; Coll, Josep (Institut Germans Trias i Pujol. IrsiCaixa) ; Bravo, Isabel (Hospital Universitari Germans Trias i Pujol) ; Estany, Carla (Hospital Universitari Germans Trias i Pujol) ; Herrero, Cristina (Hospital Universitari Germans Trias i Pujol) ; Saz, Jorge (BCN Checkpoint,) ; Sirera, Guillem (Hospital Universitari Germans Trias i Pujol) ; Torrela, Ariadna (Hospital Universitari Vall d'Hebrón) ; Navarro, Jordi (Hospital Universitari Vall d'Hebrón) ; Crespo, Manel (Hospital Universitari Vall d'Hebrón) ; Brander, Christian (Institut Germans Trias i Pujol. IrsiCaixa) ; Negredo, Eugènia (Universitat de Vic) ; Blanco, Julià (Institut Germans Trias i Pujol. IrsiCaixa) ; Guarner, Francisco (Hospital Universitari Vall d'Hebrón) ; Calle, Maria Luz (Universitat de Vic) ; Bork, Peer (European Molecular Biology Laboratory) ; Sönnerborg, Anders (Karolinska Universitetssjukhuset) ; Clotet, Bonaventura (Institut Germans Trias i Pujol. IrsiCaixa) ; Paredes, Roger (Institut Germans Trias i Pujol. IrsiCaixa)
The precise effects of HIV-1 on the gut microbiome are unclear. Initial cross-sectional studies provided contradictory associations between microbial richness and HIV serostatus and suggested shifts from Bacteroides to Prevotella predominance following HIV-1 infection, which have not been found in animal models or in studies matched for HIV-1 transmission groups. [...]
2016 - 10.1016/j.ebiom.2016.01.032
EBioMedicine, Vol. 5 (March 2016) , p. 135-146  
5.
23 p, 3.3 MB A human immune data-informed vaccine concept elicits strong and broad T-cell specificities associated with HIV-1 control in mice and macaques / Mothe Pujadas, Beatriz (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Hu, Xintao (National Cancer Institute at Frederick (Frederick, Estats Units d'Amèrica)) ; Llano Montero, Anuska (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Rosati, Margherita (National Cancer Institute at Frederick (Frederick, Estats Units d'Amèrica)) ; Olvera, Alex (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Kulkarni, Viraj (National Cancer Institute at Frederick (Frederick, Estats Units d'Amèrica)) ; Valentin, Antonio (National Cancer Institute at Frederick (Frederick, Estats Units d'Amèrica)) ; Alicea, Cándido (National Cancer Institute at Frederick (Frederick, Estats Units d'Amèrica)) ; Pilkington, Guy R. (National Cancer Institute at Frederick (Frederick, Estats Units d'Amèrica)) ; Sardesai, Niranjan Y. (Inovio Pharmaceuticals) ; Rocafort, Muntsa (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Crespo, Manel (Hospital Universitari Vall d'Hebron) ; Carrillo, Jorge (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Marco, Andrés (Centre Penitenciari d'Homes (Barcelona, Catalunya)) ; Mullins, James I. (University of Washington (Estats Units d'Amèrica)) ; Dorrell, Lucy (John Radcliffe Hospital (Oxford, Regne Unit)) ; Hanke, Tomáš (University of Oxford (Regne Unit)) ; Clotet i Sala, Bonaventura (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Pavlakis, George N. (National Cancer Institute at Frederick (Frederick, Estats Units d'Amèrica)) ; Felber, Barbara K. (National Cancer Institute at Frederick (Frederick, Estats Units d'Amèrica)) ; Brander, Christian (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Universitat Autònoma de Barcelona
BACKGROUND: None of the HIV T-cell vaccine candidates that have reached advanced clinical testing have been able to induce protective T cell immunity. A major reason for these failures may have been suboptimal T cell immunogen designs. [...]
2015 - 10.1186/s12967-015-0392-5
Journal of translational medicine, Vol. 13 Núm. 60 (february 2015)  

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