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14 p, 3.6 MB |
Interaction between FKBP5 variability and recent life events in the anxiety spectrum : Evidence for the differential susceptibility model
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Pérez-Pérez, Beatriz (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Cristóbal-Narváez, Paula (Centro de Investigación Biomédica en Red de Salud Mental) ;
Sheinbaum Frank, Tamara (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Kwapil, Thomas R. (University of Illinois. Department of Psychology) ;
Ballespí Sola, Sergi (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Peña, Elionora (Universitat de Barcelona. Institut de Biomedicina) ;
de Castro-Catala, Marta (Universitat de Barcelona. Institut de Biomedicina) ;
Riba, Maria Dolors (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Rosa, Araceli (Universitat de Barcelona. Institut de Biomedicina) ;
Barrantes-Vidal, Neus (Sant Pere Claver-Fundació Sanitària)
Gene-environment interaction (GxE) research has highlighted the importance of investigating the FK506 binding protein 51 (FKBP5) gene as a sensitivity gene. However, previous GxE studies with FKBP5 have not measured the full environmental spectrum or applied statistical tests to discern whether the GxE interaction fits better with the differential-susceptibility or diathesis-stress hypotheses. [...]
2018 -  10.1371/journal.pone.0193044
PloS one, Vol. 13 (february 2018)
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13 p, 661.0 KB |
Efficacy, cost-utility and physiological effects of Acceptance and Commitment Therapy (ACT) and Behavioural Activation Treatment for Depression (BATD) in patients with chronic low back pain and depression : study protocol of a randomised, controlled trial including mobile-technology-based ecological momentary assessment (IMPACT study)
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Sanabria-Mazo, Juan P (Universitat Autònoma de Barcelona. Departament de Psicologia Bàsica, Evolutiva i de l'Educació) ;
García Forero, Carlos (International University of Catalunya. Department of Medicine) ;
Cristóbal Narváez, Paula (Parc Sanitari Sant Joan de Deu (Sant Boi de Llobregat)) ;
Suso-Ribera, Carlos (Universitat Jaume I. Department of Basic and Clinical Psychology and Psychobiology) ;
García-Palacios, Azucena (Universitat Jaume I. Department of Basic and Clinical Psychology and Psychobiology) ;
Colomer-Carbonell, Ariadna (Universitat Autònoma de Barcelona. Departament de Psicologia Bàsica, Evolutiva i de l'Educació) ;
Pérez-Aranda, Adrián (Universitat Autònoma de Barcelona. Departament de Psicologia Bàsica, Evolutiva i de l'Educació) ;
Andrés-Rodríguez, Laura (Universitat Autònoma de Barcelona. Departament de Psicologia Bàsica, Evolutiva i de l'Educació) ;
McCracken, Lance (Uppsala University. Psychology Department) ;
D'Amico, Francesco (London School of Economics and Political Science. Personal Social Services Research Unit) ;
Estivill, Pere (Parc Sanitari Sant Joan de Deu) ;
Carreras-Marcos, Bernat (Parc Sanitari Sant Joan de Deu) ;
Montes-Pérez, Antonio (Consorci Parc de Salut MAR de Barcelona) ;
Comps, Olga (Consorci Parc de Salut MAR de Barcelona) ;
Esteve, Montserrat (Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición) ;
Grasa, Mar (Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición) ;
Rosa, Araceli (Centro de Investigación Biomédica en Red de Salud Mental) ;
Cuesta-Vargas, Antonio I (Queensland University of Technology (Brisbane, Queensland). Faculty of Health) ;
Maes, Michael (Chulalongkorn University. Department of Psychiatry) ;
Borràs, Xavier (Universitat Autònoma de Barcelona. Departament de Psicologia Bàsica, Evolutiva i de l'Educació) ;
Edo Izquierdo, Sílvia (Universitat Autònoma de Barcelona. Departament de Psicologia Bàsica, Evolutiva i de l'Educació) ;
Sanz Ruiz, Antoni (Universitat Autònoma de Barcelona. Departament de Psicologia Bàsica, Evolutiva i de l'Educació) ;
Feliu-Soler, Albert (Universitat Autònoma de Barcelona. Departament de Psicologia Bàsica, Evolutiva i de l'Educació) ;
Castaño Asins, Juan Ramon (Consorci Parc de Salut MAR de Barcelona) ;
Luciano, Juan V (Parc Sanitari Sant Joan de Deu)
The IMPACT study focuses on chronic low back pain (CLBP) and depression symptoms, a prevalent and complex problem that represents a challenge for health professionals. Acceptance and Commitment Therapy (ACT) and Brief Behavioural Activation Treatment for Depression (BATD) are effective treatments for patients with persistent pain and depression, respectively. [...]
2020 - 10.1136/bmjopen-2020-038107
BMJ open, Vol. 10 (july 2020)
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13 p, 636.7 KB |
Relatives' attachment anxiety mediates the association between perceived loss and expressed emotion in early psychosis
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Hinojosa-Marqués, Lídia (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Domínguez Martínez, Tecelli (Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz) ;
Sheinbaum Frank, Tamara (University of Southern California. Department of Psychology) ;
Cristóbal-Narváez, Paula (Parc Sanitari Sant Joan de Déu) ;
Kwapil, Thomas (University of Illinois at Urbana-Champaign) ;
Barrantes-Vidal, Neus (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut)
A common reaction experienced by family members of patients with psychosis is grief for the loss of their healthy relative. Importantly, high levels of perceived loss have been related to the manifestation of high expressed emotion (EE), which includes the negative attitudes expressed by relatives toward an ill family member. [...]
2019 - 10.1371/journal.pone.0223425
PloS one, Vol. 14, núm. 10 (2019) , p. e0223425
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11 p, 955.3 KB |
The genome-wide associated candidate gene ZNF804A and psychosis-proneness : evidence of sex-modulated association
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De Castro-Catala, Marta (Universitat de Barcelona. Institut de Biomedicina) ;
Mora-Solano, Aurea (Universitat de Barcelona. Departament de Biologia Evolutiva, Ecologia i Ciències Ambientals) ;
Kwapil, Thomas (Department of Psychology, University of Illinois at Champaign-Urbana) ;
Cristóbal Narváez, Paula (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Sheinbaum Frank, Tamara (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Racioppi, Anna (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Barrantes-Vidal, Neus (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Rosa, Araceli (Universitat de Barcelona. Departament de Biologia Evolutiva, Ecologia i Ciències Ambientals)
BACKGROUND: The Zinc finger protein 804A (ZNF804A) is a promising candidate gene for schizophrenia and the broader psychosis phenotype that emerged from genome-wide association studies. It is related to neurodevelopment and associated to severe symptoms of schizophrenia and alterations in brain structure, as well as positive schizotypal personality traits in non-clinical samples. [...]
2017 - 10.1371/journal.pone.0185072
PloS one, Vol. 12, núm. 9 (2017) , p. e0185072
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11 p, 284.9 KB |
The role of stress-regulation genes in moderating the association of stress and daily-life psychotic experiences
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Cristóbal-Narváez, Paula (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Sheinbaum Frank, Tamara (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Myin-Germeys, Inez (Katholieke Universiteit Leuven. Departement Neurowetenschappen) ;
Kwapil, Thomas (University of Illinois at Urbana-Champaign) ;
De Castro-Catala, Marta (Universitat de Barcelona. Institut de Biomedicina) ;
Domínguez Martínez, Tecelli (Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz) ;
Racioppi, Anna (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Monsonet, Manel (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Hinojosa-Marqués, Lídia (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
van Winkel, R. (Katholieke Universiteit Leuven. Departement Neurowetenschappen) ;
Rosa, Araceli (Universitat de Barcelona. Departament de Biologia Evolutiva, Ecologia i Ciències Ambientals) ;
Barrantes-Vidal, Neus (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut)
The interaction of single nucleotide polymorphisms with both distal and proximal environmental factors across the extended psychosis phenotype is understudied. This study examined (i) the interaction of relevant SNPs with both early-life adversity and proximal (momentary) stress on psychotic experiences (PEs) in an extended psychosis sample; and (ii) differences between early-psychosis and non-clinical groups for these interactions. [...]
2017 - 10.1111/acps.12789
Acta psychiatrica Scandinavica, Vol. 136, issue 4 (Oct. 2017) , p. 389-399
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14 p, 384.0 KB |
The Interaction between Childhood Bullying and the FKBP5 Gene on Psychotic-Like Experiences and Stress Reactivity in Real Life
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Cristóbal Narváez, Paula (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Sheinbaum Frank, Tamara (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Rosa, Araceli (Universitat de Barcelona. Departament de Biologia Evolutiva, Ecologia i Ciències Ambientals) ;
Ballespí Sola, Sergi (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Castro-Catala, Marta de (Universitat de Barcelona. Departament de Biologia Evolutiva, Ecologia i Ciències Ambientals) ;
Peña, Elionora (Universitat de Barcelona. Departament de Biologia Evolutiva, Ecologia i Ciències Ambientals) ;
Kwapil, Thomas (University of North Carolina at Greensboro. Department of Psychology) ;
Barrantes-Vidal, Neus (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut)
Aim: The present study employed Experience Sampling Methodology to examine whether the interaction between childhood bullying and FKBP5 variability (i) is associated with the expression of psychotic-like experiences, paranoia, and negative affect, and (ii) moderates psychotic-like, paranoid, and affective reactivity to different forms of momentary stress (situational and social) in daily life. [...]
2016 - 10.1371/journal.pone.0158809
PloS one, Vol. 11, Num. 7 (July 2016) , p. 1-14
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15 p, 415.8 KB |
Impact of Adverse Childhood Experiences on Psychotic-Like Symptoms and Stress Reactivity in Daily Life in Nonclinical Young Adults
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Cristóbal Narváez, Paula (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Sheinbaum Frank, Tamara (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Ballespí Sola, Sergi (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Mitjavila i Garcia, Mercè (Universitat Autònoma de Barcelona. Departament de Psicologia de la Salut i Psicologia Social) ;
Myin-Germeys, Inez (Center for Contextual Psychiatry (Leuven, Bèlgica)) ;
Kwapil, Thomas (University of North Carolina at Greensboro. Department of Psychology) ;
Barrantes-Vidal, Neus (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut)
Background: There is increasing interest in elucidating the association of different childhood adversities with psychosis-spectrum symptoms as well as the mechanistic processes involved. This study used experience sampling methodology to examine (i) associations of a range of childhood adversities with psychosis symptom domains in daily life; (ii) whether associations of abuse and neglect with symptoms are consistent across self-report and interview methods of trauma assessment; and (iii) the role of different adversities in moderating affective, psychotic-like, and paranoid reactivity to situational and social stressors. [...]
2016 - 10.1371/journal.pone.0153557
PloS one, Vol. 11 Núm. 4 (April 2016) , p. 1-15
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11 p, 711.3 KB |
D-cycloserine in prelimbic cortex reverses scopolamine-induced deficits in olfactory memory in rats
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Portero Tresserra, Marta (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Cristóbal Narváez, Paula (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Martí Nicolovius, Margarita (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Guillazo i Blanch, Gemma (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Vale Martínez, Anna (Universitat Autònoma de Barcelona. Institut de Neurociències)
A significant interaction between N-methyl-D-aspartate (NMDA) and muscarinic receptors has been suggested in the modulation of learning and memory processes. The present study further investigates this issue and explores whether dcycloserine (DCS), a partial agonist at the glycine binding site of the NMDA receptors that has been regarded as a cognitive enhancer, would reverse scopolamine (SCOP)-induced amnesia in two olfactory learning tasks when administered into the prelimbic cortex (PLC). [...]
2013 - 10.1371/journal.pone.0070584
PloS one, Vol. 8 No. 8 (Agost 2013) , p. e70584
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