Curtin, James - Search Results - UAB Digital Repository of Documents

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Articles, 5 records found

Articles	5 records found

11 p, 2.7 MB

Cold Atmospheric Plasma Induces ATP-Dependent Endocytosis of Nanoparticles and Synergistic U373MG Cancer Cell Death / He, Zhonglei (Dublin Institute of Technology) ; Liu, Kangze (Dublin Institute of Technology) ; Manaloto, Eline (Dublin Institute of Technology) ; Casey, Alan (Dublin Institute of Technology) ; Cribaro, George Paul (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Byrne, Hugh J. (Dublin Institute of Technology) ; Tian, Furong (Dublin Institute of Technology) ; Barcia, Carlos (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Conway, Gillian E. (Dublin Institute of Technology) ; Cullen, Patrick J. (University of Nottingham) ; Curtin, James (Dublin Institute of Technology)
Gold nanoparticles (AuNP) have potential as both diagnostic and therapeutic vehicles. However, selective targeting and uptake in cancer cells remains challenging. Cold atmospheric plasma (CAP) can be combined with AuNP to achieve synergistic anti-cancer cytotoxicity. [...]
2018 - DOI (Digital Object Identifier)

10.1038/s41598-018-23262-0
Scientific reports, Vol. 8 (march 2018)

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16 p, 3.1 MB

Ursolic Acid Inhibits Collective Cell Migration and Promotes JNK-Dependent Lysosomal Associated Cell Death in Glioblastoma Multiforme Cells / Conway, Gillian E. (In-Vitro Toxicology Group, Institute of Life Science, Swansea University Medical School) ; Zizyte, Deimante (School of Food Science and Environmental Health, Technological University Dublin) ; Mondala, Julie Rose Mae (School of Food Science and Environmental Health, Technological University Dublin) ; He, Zhonglei (Environmental Sustainability and Health Institute (ESHI) and FOCAS Research Institute, Technological University Dublin) ; Lynam, Lorna (School of Food Science and Environmental Health, Technological University Dublin) ; Lecourt, Mathilde (School of Food Science and Environmental Health, Technological University Dublin) ; Barcia, Carlos (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Howe, Orla (School of Biological Sciences and Health Sciences, Technological University Dublin) ; Curtin, James (Dublin Institute of Technology. School of Food Science and Environmental Health)
Ursolic acid (UA) is a bioactive compound which has demonstrated therapeutic efficacy in a variety of cancer cell lines. UA activates various signalling pathways in Glioblastoma multiforme (GBM) and offers a promising starting point in drug discovery; however, understanding the relationship between cell death and migration has yet to be elucidated. [...]
2021 - DOI (Digital Object Identifier)

10.3390/ph14020091
Pharmaceuticals, Vol. 14 (january 2021)

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12 p, 2.3 MB

Cold atmospheric plasma induces accumulation of lysosomes and caspase-independent cell death in U373MG glioblastoma multiforme cells / Conway, Gillian E. (Technological University Dublin. School of Food Science & Environmental Health) ; He, Zhonglei (Technological University Dublin. Environmental Sustainability & Health Institute) ; Hutanu, Ana Lacramioara (Trinity College Dublin. School of Biochemistry & Immunology) ; Cribaro, eorge Paul (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Manaloto, Eline (Technological University Dublin. Environmental Sustainability & Health Institute) ; Casey, Alan (FOCAS Research Institute) ; Traynor, Damien (FOCAS Research Institute) ; Milosavljevic, Vladimir (Technological University Dublin. School of Physics & Clinical & Optometric Sciences) ; Howe, Orla (FOCAS Research Institute) ; Barcia, Carlos (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Murray, James T. (Trinity College Dublin. School of Biochemistry & Immunology) ; Cullen, Patrick J. (University of Sydney. School of Chemical and Biomolecular Engineering) ; Curtin, James (FOCAS Research Institute)
Room temperature Cold Atmospheric Plasma (CAP) has shown promising efficacy for the treatment of cancer but the exact mechanisms of action remain unclear. Both apoptosis and necrosis have been implicated as the mode of cell death in various cancer cells. [...]
2019 - DOI (Digital Object Identifier)

10.1038/s41598-019-49013-3
Scientific reports, Vol. 9 (2019) , art. 12891

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2 p, 165.1 KB

Editorial - Glial Cells : Managers of Neuro-Immunity / Barcia, Carlos (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Guillemin, Gilles J. (Macquarie University. Department of Biomedical Sciences) ; Curtin, James (Dublin Institute of Technology. School of Food Science & Environmental Health) ; Zirger, Jeffrey M. (U.S. Centers for Disease Control and Prevention) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular
After many decades of study in the field of Neuroscience that were mostly centered on the neuron there is a mounting interest in the study of the function of the glial cells in many aspects and functions of the central nervous system. [...]
2016 - DOI (Digital Object Identifier)

10.3389/fncel.2016.00060
Frontiers in cellular neuroscience, Vol. 10 (March 2016) , art.60

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4 p, 1.2 MB

Immunology and the central nervous system / Barcia, Carlos (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Curtin, James (Dublin Institute of Technology. School of Food Science and Environmental Health) ; Zirger, Jeffrey M (Centers for Disease Control and Prevention (Estats Units d'Amèrica)) ; Larocque, Daniel (GlaxoSmithKline)
2013 - DOI (Digital Object Identifier)

10.1155/2013/512684
Clinical and Developmental Immunology, Vol. 2013, article ID 512684 (2013)

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