Results overview: Found 3 records in 0.02 seconds.
Articles, 2 records found
Research literature, 1 records found
Articles 2 records found  
1.
13 p, 3.9 MB Accelerated geroncogenesis in hereditary breast-ovarian cancer syndrome / Menendez, Javier A. (Institut d'Investigació Biomèdica de Girona) ; Folguera-Blasco, Núria (Centre de Recerca Matemàtica) ; Cuyàs Navarro, Elisabet (Institut d'Investigació Biomèdica de Girona) ; Fernández-Arroyo, Salvador (Hospital Universitari de Sant Joan) ; Joven, Jorge (Hospital Universitari de Sant Joan) ; Alarcón Cor, Tomás (Universitat Autònoma de Barcelona. Departament de Matemàtiques)
The geroncogenesis hypothesis postulates that the decline in metabolic cellular health that occurs naturally with aging drives a "field effect" predisposing normal tissues for cancer development. We propose that mutations in the cancer susceptibility genes BRCA1/2 might trigger "accelerated geroncogenesis" in breast and ovarian epithelia. [...]
2016 - 10.18632/oncotarget.7867
Oncotarget, Vol. 7, issue 11 (March 2016) , p. 11959-11971  
2.
4 p, 1.6 MB Metabostemness : metaboloepigenetic reprogramming of cancer stem-cell functions / Menendez, Javier A. (Institut Català d'Oncologia) ; Corominas-Faja, Bruna (Institut Català d'Oncologia) ; Cuyàs Navarro, Elisabet (Institut Català d'Oncologia) ; Alarcón Cor, Tomás (Centre de Recerca Matematica)
Cancer researchers are currently embarking on one of their field's biggest challenges, namely the understanding of how cellular metabolism or certain classes of elite metabolites (e. g. , oncometabolites) can directly influence chromatin structure and the functioning of epi-transcriptional circuits to causally drive tumour formation. [...]
2014
Oncoscience, Vol. 1 (Dec. 2014) , p. 803-806  

Research literature 1 records found  
1.
235 p, 2.8 MB Pharmacogenetic mechanisms (COMT and hSERT) modulating deleterious effects of MDMA and cannabis on cognitive performance in drug users / Cuyàs Navarro, Elisabet ; Torre Fornell, Rafael de la, dir. (Institut Municipal d'Investigació Mèdica (Barcelona, Catalunya)) ; Farré Albaladejo, Magí, tutor (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia
La neurotransmissió dopaminèrgica i serotonèrgica al còrtex preforntal i a les regions del sistema límbic són un dels principals substrats cerebrals de les funcions executives (implicades en l'organització i el control) i la regulació emocinal. [...]
The serotonergic and dopaminegic neurotransmission at the prefrontal-cortex and the areas related to the limbic system, are one of the main substrates for the executive functions (involved in different tasks such as organization and control). [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2011  

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