Results overview: Found 2 records in 0.02 seconds.
Articles, 2 records found
Articles 2 records found  
1.
9 p, 3.4 MB Targeting antitumoral proteins to breast cancer by local administration of functional inclusion bodies / Pesarrodona Roches, Mireia (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Jauset, Toni (Vall d'Hebron Institut d'Oncologia) ; Díaz Riascos, Zamira Vanessa (Centro de Investigación Biomédica en Red) ; Sánchez Chardi, Alejandro (Universitat de Barcelona. Departament de Biologia Evolutiva, Ecologia i Ciències Ambientals) ; Beaulieu, Marie-Eve (Vall d'Hebron Institut d'Oncologia) ; Seras-Franzoso, Joaquin (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Sánchez García, Laura (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Baltà Foix, Ricardo. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Mancilla, Sandra (Centro de Investigación Biomédica en Red) ; Fernández Caparrós, Yolanda (Centro de Investigación Biomédica en Red) ; Rinas, Ursula (Leibniz University of Hannover. Helmholtz Centre for Infection Research) ; Schwartz, Simó (Centro de Investigación Biomédica en Red) ; Soucek, Laura (Vall d'Hebron Institut d'Oncologia) ; Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Abasolo, Ibane (Centro de Investigación Biomédica en Red) ; Vázquez Gómez, Esther (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
Two structurally and functionally unrelated proteins, namely Omomyc and p31, are engineered as CD44-targeted inclusion bodies produced in recombinant bacteria. In this unusual particulate form, both types of protein materials selectively penetrate and kill CD44 tumor cells in culture, and upon local administration, promote destruction of tumoral tissue in orthotropic mouse models of human breast cancer. [...]
2019 - 10.1002/advs.201900849
Advanced science, Vol. 6, issue 18 (Sep. 2019) , art. 1900849  
2.
18 p, 3.3 MB Pivotal role of AKT2 during dynamic phenotypic change of breast cancer stem cells / Gener, Petra (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Rafael, D. (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ; Seras-Franzoso, Joaquin (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Perez, A. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Alamo Pindado, Luis (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Casas, Glòria (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Arango, Diego (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Fernández Caparrós, Yolanda (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Díaz Riascos, Zamira Vanessa. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Abasolo, Ibane. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Schwartz, Simó (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Therapeutic resistance seen in aggressive forms of breast cancer remains challenging for current treatments. More than half of the patients suffer from a disease relapse, most of them with distant metastases. [...]
2019 - 10.3390/cancers11081058
Cancers, Vol. 11 Núm. 8 (august 2019) , p. 1058  

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