Resultados globales: 2 registros encontrados en 0.02 segundos.
Artículos, Encontrados 2 registros
Artículos Encontrados 2 registros  
1.
14 p, 4.6 MB Genetic heterogeneity and actionable mutations in HER2-positive primary breast cancers and their brain metastases / De Mattos-Arruda, Leticia (Department of Pathology, Memorial Sloan Kettering Cancer Center) ; Ng, Charlotte K. Y. (Department of Biomedicine, University of Basel, Basel, Switzerland) ; Piscuoglio, Salvatore (Institute of Pathology, University Hospital Basel) ; Gonzalez-Cao, Maria (Hospital Universitari Quirón Dexeus) ; Lim, Raymond S. (Department of Pathology, Memorial Sloan Kettering Cancer Center) ; De Filippo, Maria R. (Department of Pathology, Memorial Sloan Kettering Cancer Center) ; Fusco, Nicola (Department of Pathology, Memorial Sloan Kettering Cancer Center) ; Schultheis, Anne M. (Department of Pathology, Memorial Sloan Kettering Cancer Center) ; Ortiz, Carolina (Vall d'Hebron Institut d'Oncologia) ; Viteri, Santiago (Hospital Universitari Quirón Dexeus) ; Arias, Alexandra (Vall d'Hebron Institut d'Oncologia) ; Macedo, Gabriel S. (Department of Pathology, Memorial Sloan Kettering Cancer Center) ; Oliveira, Mafalda (Vall d'Hebron Institut d'Oncologia) ; Gomez, Patricia (Vall d'Hebron Institut d'Oncologia) ; Teixidó, Cristina (Hospital Universitari Quirón Dexeus) ; Nuciforo, Paolo (Vall d'Hebron Institut d'Oncologia) ; Peg, Vicente (Vall d'Hebron Institut de Recerca) ; Saura, Cristina (Vall d'Hebron Institut d'Oncologia) ; Ramon y Cajal, Santiago (Vall d'Hebron Institut de Recerca) ; Tresserra Casas, Francesc (Hospital Universitari Quirón Dexeus) ; Weigelt, Britta (Department of Pathology, Memorial Sloan Kettering Cancer Center) ; Cortes, Javier (Universitat Autònoma de Barcelona. Departament de Medicina) ; Seoane Suárez, Joan (Institució Catalana de Recerca i Estudis Avançats (ICREA)) ; Reis-Filho, Jorge S. (Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center)
Brain metastases constitute a challenge in the management of patients with HER2-positive breast cancer treated with anti-HER2 systemic therapies. Here we sought to define the repertoire of mutations private to or enriched for in HER2-positive brain metastases. [...]
2018 - 10.18632/oncotarget.25041
Oncotarget, Vol. 9 (april 2018) , p. 20617-20630  
2.
12 p, 2.2 MB MicroRNA-21 links epithelial-to-mesenchymal transition and inflammatory signals to confer resistance to neoadjuvant trastuzumab and chemotherapy in HER2-positive breast cancer patients / De Mattos-Arruda, Leticia (Institut d'Oncologia de la Vall Hebron) ; Bottai, Giulia (Oncology Experimental Therapeutics Unit. IRCCS Humanitas Clinical and Research Institute (Italy)) ; Nuciforo, Paolo Giovanni (Institut d'Oncologia de la Vall Hebron) ; Di Tommaso, Luca (Division of Pathology. IRCCS Humanitas Clinical and Research Institute (Italy)) ; Giovannetti, Elisa (University of Pisa. Cancer Pharmacology Laboratory. AIRC Start-Up Unit (Italy)) ; Peg, Vicente (Hospital Universitari Vall d'Hebron. Departament de Patologia) ; Losurdo, Agnese (Division of Oncology and Hematology. IRCCS Humanitas Clinical and Research Institute (Italy)) ; Pérez-Garcia, José (Institut d'Oncologia de la Vall Hebron) ; Masci, Giovanna (Division of Oncology and Hematology. IRCCS Humanitas Clinical and Research Institute (Italy)) ; Corsi, Fabio (University of Milan. Deparment of Clinical and Biomedical Sciences "Luigi Sacco" (Italy)) ; Cortés, Javier (Hospital Universitario Ramón y Cajal) ; Seoane Suárez, Joan (Institut d'Oncologia de la Vall Hebron) ; Calin, George A. (The University of Texas MD Anderson Cancer Center (USA)) ; Santarpia, Libero (Oncology Experimental Therapeutics Unit. IRCCS Humanitas Clinical and Research Institute (Italy)) ; Universitat Autònoma de Barcelona
Patients with primary HER2-positive breast cancer benefit from HER2-targeted therapies. Nevertheless, a significant proportion of these patients die of disease progression due to mechanisms of drug resistance. [...]
2015 - 10.18632/oncotarget.5495
Oncotarget, Vol. 6, Num. 35 (October 2015) , p. 37269-37280  

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