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1.
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7 p, 314.9 KB |
Epithelial-Mesenchymal Transition in the Resistance to Somatostatin Receptor Ligands in Acromegaly
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Gil, Joan (Institut Germans Trias i Pujol) ;
Jordà, Mireia (Institut Germans Trias i Pujol) ;
Soldevila, Berta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Puig Domingo, Manuel (Universitat Autònoma de Barcelona. Departament de Medicina)
Epithelial-mesenchymal transition (EMT) is a dynamic process by which epithelial cells loss their phenotype and acquire mesenchymal traits, including increased migratory and invasive capacities. EMT is involved in physiological processes, such as embryogenesis and wound healing, and in pathological processes such as cancer, playing a pivotal role in tumor progression and metastasis. [...]
2021 -  10.3389/fendo.2021.646210
Frontiers in Endocrinology, Vol. 12 (march 2021)
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2.
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5 p, 253.5 KB |
Lung ultrasound and biomarkers in primary care : Partners for a better management of patients with heart failure?
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Domingo, Mar (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Conangla, Laura (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Lupón, Josep (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Wilke, Asunción (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Juncà Puig, Gladys (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Revuelta-López, E. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Tejedor, Xavier (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Bayés-Genís, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina)
The association of pulmonary congestion assessed by lung ultrasound (LUS) and biomarkers-other than N-terminal pro-brain natriuretic peptide (NT-proBNP)-is uncertain. We investigated the relationship between total B-line count by LUS and several biomarkers in outpatients with suspicion of heart failure (HF). [...]
2020 - 10.33393/jcb.2020.2164
Journal of Circulating Biomarkers, Vol. 9 (october 2020) , p. 8-12
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3.
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15 p, 1.7 MB |
Epigenetic footprint enables molecular risk stratification of hepatoblastoma with clinical implications
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Carrillo-Reixach, Juan (Institut Germans Trias i Pujol) ;
Torrens, L. (Translational research in Hepatic Oncology. Liver Unit. Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS). Hospital Clínic. Universitat de Barcelona) ;
Simón-Coma, Marina (Institut Germans Trias i Pujol) ;
Royo, Laura (Institut Germans Trias i Pujol) ;
Domingo-Sàbat, Montse (Institut Germans Trias i Pujol) ;
Abril-Fornaguera, J. (Translational research in Hepatic Oncology. Liver Unit. Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS). Hospital Clínic. Universitat de Barcelona) ;
Akers, N. (Department of Genetics and Genomic Sciences. The Icahn Institute for Genomics and Multiscale Biology. Icahn School of Medicine at Mount Sinai) ;
Sala Llinas, Margarita (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Ragull, Sonia (Institut Germans Trias i Pujol) ;
Arnal, Magdalena (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Villalmanzo, Núria (Institut Germans Trias i Pujol) ;
Cairo, S. (Instituto di Ricerca Pediatrica. Corso Stati Uniti 4) ;
Villanueva, A. (Chemoresistance and Predictive Factors Group. Program Against Cancer Therapeutic Resistance. Catalan Institute of Oncology (ICO). Bellvitge Biomedical Research Institute. L'Hospitalet del Llobregat) ;
Kappler, R. (Department of Pediatric Surgery. Dr. von Hauner Children's Hospital. Ludwig-Maximilians-University Munich) ;
Garrido-Portnou, Marta (Hospital Universitari Vall d'Hebron) ;
Guerra, Laura (University Hospital La Paz. Pathology Department) ;
Sábado, Constantino (Hospital Universitari Vall d'Hebron) ;
Guillén, Ganriela (Hospital Universitari Vall d'Hebron) ;
Mallo, Maria del Mar (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Piñeyro, David (Institut Germans Trias i Pujol) ;
Vázquez-Vitali, María (Institut Germans Trias i Pujol) ;
Kuchuk, O. (Mount Sinai Liver Cancer Program. Divisions of Liver Diseases. Tisch Cancer Institute. Icahn School of Medicine at Mount Sinai) ;
Mateos, M.E. (Pediatric Oncology Unit. Department of Pediatrics. University Hospital Reina Sofía) ;
Ramírez, G. (University Hospital Universitario Virgen del Rocío. Pediatric Oncology Department) ;
Santamaría, M.L. (University Hospital La Paz. Pediatric Surgery Department) ;
Mozo, Y. (University Hospital La Paz. Pediatric Oncology Department) ;
Soriano, A. (Hospital Universitari Val d'Hebron. Institut de Recerca) ;
Grotzer, M. (Department of Pediatric Oncology. University Children's Hospital Zurich. University of Zurich) ;
Branchereau, S. (Bicêtre Hospital) ;
de Andoin, N.G. (Pediatric Oncology. Hospital Universitario Donostia) ;
López-Ibor, B. (Department of Pediatric Hematology and Oncology. HM Montepríncipe Hospital) ;
López-Almaraz, R. (Pediatric Oncology and Hematology. Hospital Universitario Cruces) ;
Salinas, J.A. (Division of Hematology-Oncology. Department of Pediatrics. Hospital Universitari Son Espases) ;
Torres, B. (Medical Oncology Department. Pediatric Oncology Department. University Hospital La Fe) ;
Hernández, F. (University Hospital La Paz. Pediatric Surgery Department) ;
Uriz, J.J. (Pediatric Oncology. Hospital Universitario Donostia) ;
Fabre, M. (Department of Pathology. Hôpital Universitaire Necker-Enfants Malades. Assistance Publique-Hôpitaux de Paris. Université Paris Descartes) ;
Blanco, J. (Universitat de Vic. Universitat Central de Catalunya) ;
Paris, C. (Stem Cell Transplant Unit. Hospital Luis Calvo Mackenna) ;
Bajčiová, V. (Department of Pediatric Oncology. Childrens University Hospital Brno) ;
Laureys, G. (Department of Pediatric Hematology. Oncology and Hematopoietic Stem Cell Transplantation. Ghent University Hospital) ;
Masnou, Helena (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Clos, Ariadna (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Belendez, C. (Hospital Gregorio Marañón (Madrid)) ;
Guettier, C. (Bicêtre Hospital) ;
Sumoy, Lauro (Institut Germans Trias i Pujol) ;
Planas, Ramón (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Jordà, Mireia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Nonell, Lara (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Czauderna, P. (Department of Surgery and Urology for Children and Adolescents. Medical University of Gdansk) ;
Morland, B. (Department of Oncology. Birmingham Women's and Children's Hospital) ;
Sia, D. (Mount Sinai Liver Cancer Program. Divisions of Liver Diseases. Tisch Cancer Institute. Icahn School of Medicine at Mount Sinai) ;
Losic, B. (Icahn Institute for Data Science and Genomic Technology. Icahn School of Medicine at Mount Sinai) ;
Buendia, M.A. (INSERM. UMR 1193. Paul-Brousse Hospital. Hepatobiliary Centre) ;
Sarrias, Maria-Rosa (Institut Germans Trias i Pujol) ;
Llovet, J.M. (Institució Catalana de Recerca i Estudis Avançats (ICREA)) ;
Armengol, Carolina (Institut Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
Background & Aims: Hepatoblastoma (HB) is a rare disease. Nevertheless, it is the predominant pediatric liver cancer, with limited therapeutic options for patients with aggressive tumors. Herein, we aimed to uncover the mechanisms of HB pathobiology and to identify new biomarkers and therapeutic targets in a move towards precision medicine for patients with advanced HB. [...]
2020 - 10.1016/j.jhep.2020.03.025
Journal of Hepatology, Vol. 73 Núm. 2 (august 2020) , p. 328-341
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4.
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16 p, 20.5 MB |
Immunogenicity and Protection against Mycobacterium caprae Challenge in Goats Vaccinated with BCG and Revaccinated after One Year
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Arrieta Villegas, Claudia (Universitat Autònoma de Barcelona. Centre de Recerca en Sanitat Animal) ;
Martin, Maite (Universitat Autònoma de Barcelona. Centre de Recerca en Sanitat Animal) ;
Verdés Martinez, Judit (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Moll Sánchez, Xavier (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Espada Gerlach, Yvonne (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Singh, Mahavir (Lionex Diagnostics and Therapeutics GmbH) ;
Villarreal Ramos, Bernardo (Animal Health and Veterinary Laboratories Agency. TB Research Group) ;
Domingo, Mariano (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Pérez De Val, Bernat (Universitat Autònoma de Barcelona. Centre de Recerca en Sanitat Animal) ;
Vidal Barba, Enric (Universitat Autònoma de Barcelona. Centre de Recerca en Sanitat Animal)
Vaccination has been proposed as a supplementary tool for the control of tuberculosis in livestock. The long-term immunogenicity elicited by bacillus Calmette-Guerin (BCG) and the efficacy of revaccination were investigated in thirty goat kids distributed into three groups: unvaccinated controls, BCG (vaccinated at week 0) and BCG-BCG (vaccinated at weeks 0 and 56). [...]
2020 - 10.3390/vaccines8040751
Vaccines, Vol. 8 Núm. 4 (2020) , p. 751
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4 p, 196.0 KB |
Advanced remote care for heart failure in times of COVID-19 using an implantable pulmonary artery pressure sensor : the new normal
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Bayés-Genís, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Codina, Pau (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Abdul-Jawad Altisent, Omar (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Santiago, Evelyn (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Domingo, Mar (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Cediel, Germán (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Spitaleri, Giosafat (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Lupón, Josep (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Universitat Autònoma de Barcelona
Heart failure (HF) is a major public health problem and a leading cause of hospitalization in western countries. Over the past decades, the goal has been to find the best method for monitoring congestive symptoms to prevent hospitalizations. [...]
2020 - 10.1093/eurheartj/suaa169
European Heart Journal Supplements : Journal of the European Society of Cardiology, Vol. 22 (december 2020) , p. P29-P32
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11 p, 991.3 KB |
Short-term mortality in end-stage heart failure patients
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Verdú-Rotellar, Jose Maria (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Calero, Esther (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Abellana, Rosa (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Verdú-Soriano, José (Community Nursing, Preventive Medicine, Public Health and History of Science Department, Faculty of Health Sciences, University of Alicante, Spain) ;
Vinyoles, Ernest (School of Medicine, Universitat de Barcelona, Barcelona, Spain) ;
del Val-García, José Luis Institut d'Investigació en Atenció Primària Jordi Gol ;
Domingo, Mar (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Muñoz, Miguel-Angel (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Universitat Autònoma de Barcelona
This study is aimed at analyzing the impact of the main factors contributing to short and long-term mortality in patients at final stages of heart failure (HF). Patients attended at any of the 279 primary health care centers belonging to the Institut Català de la Salut, in Catalonia (Spain). [...]
2020 - 10.1016/j.aprim.2019.07.019
Atencion Primaria, Vol. 52 (january 2020) , p. 477-487
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11 p, 2.0 MB |
Long-term LVEF trajectories in patients with type 2 diabetes and heart failure : diabetic cardiomyopathy may underlie functional decline
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Julián, María Teresa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Alonso, Núria (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Lupón, Josep (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Gavidia-Bovadilla, Giovana (Hospital Clínico Universitario, INCLIVA. Cardiology Department) ;
Ferrer, Elena (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
de Antonio Ferrer, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
López-Ayerbe, Jorge (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Domingo, Mar (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Santiago-Vacas, Evelyn (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Zamora, Elisabet (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Codina, Pau (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Moliner, Pedro (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Núñez, Julio (Universitat de València. Department of Medicine) ;
Santesmases, Javier (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Puig Domingo, Manuel (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Bayés-Genís, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Left ventricular ejection fraction (LVEF) trajectories and functional recovery with current heart failure (HF) management is increasingly recognized. Type 2 diabetes mellitus (T2D) leads to a worse prognosis in HF patients. [...]
2020 - 10.1186/s12933-020-01011-w
Cardiovascular diabetology, Vol. 19 (march 2020)
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9 p, 783.7 KB |
Subclinical atherosclerosis burden predicts cardiovascular events in individuals with diabetes and chronic kidney disease
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Palanca, Ana (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Castelblanco, Esmeralda (Institut d'Investigació Biomèdica Sant Pau) ;
Betriu, Àngels (Institut de Recerca Biomèdica de Lleida. Vascular and Renal Translational Research Group) ;
Perpiñán, Hèctor (Institut de Recerca Biomèdica) ;
Soldevila, Berta (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Valdivielso, José Manuel (Institut de Recerca Biomèdica de Lleida. Vascular and Renal Translational Research Group) ;
Bermúdez-Lopez, Marcelino (Institut de Recerca Biomèdica de Lleida. Vascular and Renal Translational Research Group) ;
Puig-Jové, Carlos (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Puig Domingo, Manuel (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Groop, Per-Henrik (Monash University. Department of Diabetes, Central Clinical School) ;
Fernández, Elvira (Institut de Recerca Biomèdica de Lleida. Vascular and Renal Translational Research Group) ;
Alonso, Núria (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Mauricio Puente, Dídac (Institut d'Investigació Biomèdica Sant Pau)
Individuals with diabetes have remarkably high rates of cardiovascular morbidity and mortality. However, the incremental cardiovascular risk in diabetes is heterogeneous and has often been related to renal involvement. [...]
2019 - 10.1186/s12933-019-0897-y
Cardiovascular diabetology, Vol. 18 (july 2019)
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10.
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8 p, 1.2 MB |
Differential association between S100A4 levels and insulin resistance in prepubertal children and adult subjects with clinically severe obesity
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Taxerås, S.D. (Institut Germans Trias i Pujol) ;
Galán, M. (CIBER de Enfermedades Cardiovasculares (CIBERCV). ISCIII) ;
Campderros, L. (Biomedical Research Center (Red Fisiopatología de la Obesidad y Nutrición) (CIBEROBN). ISCIII) ;
Piquer García, Irene (Institut Germans Trias i Pujol) ;
Pellitero, Silvia (Institut Germans Trias i Pujol) ;
Martínez, E. (Institut Germans Trias i Pujol) ;
Puig, R. (Institut Germans Trias i Pujol) ;
Lucena, I. (v) ;
Tarascó, Jordi (Institut Germans Trias i Pujol) ;
Moreno, Pau (Institut Germans Trias i Pujol) ;
Balibrea, J. (Hospital Universitari Vall d'Hebron) ;
Bel, J. (Institut Germans Trias i Pujol) ;
Murillo-Vallés, Marta (Institut Germans Trias i Pujol) ;
Martínez, M. (Institut Germans Trias i Pujol) ;
Ramon-Krauel, M. (Hospital Sant Joan de Déu) ;
Puig-Domingo, M. (Institut Germans Trias i Pujol) ;
Villarroya, F. (Biomedical Research Center (Red Fisiopatología de la Obesidad y Nutrición) (CIBEROBN). ISCIII) ;
Lerin, C. (Hospital Sant Joan de Déu) ;
Sánchez-Infantes, David (Institut Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
Objectives: S100A4 has been recently identified as an adipokine associated with insulin resistance (IR) in adult subjects with obesity. However, no data about its levels in children with obesity and only a few approaches regarding its potential mechanism of action have been reported. [...]
2020 - 10.1002/osp4.381
Obesity Science and Practice, Vol. 6 Núm. 1 (january 2020) , p. 99-106
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