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Evaluation of Rapid Progressors in HIV Infection as an Extreme Phenotype / Olson, Ashley D. (University College London. Medical Research Council Clinical Trials Unit (United Kingdom)) ; Guiguet, Marguerite (Université Pierre et Marie Curie (France)) ; Zangerle, Robert (Innsbruck Medical University (Austria)) ; Gill, John (University of Calgary (Canada)) ; Pérez-Hoyos, Santiago (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Lodi, Sara (Instituto de Salud Carlos III) ; Ghosn, Jade (CHU Bicêtre. Service de Médecine Interne et Maladies Infectieuses (France)) ; Dorrucci, Maria (Istituto Superiore di Sanità (Italy)) ; Johnson, Anne (University College London. Institute of Epidemiology and Health Care (United Kingdom)) ; Sannes, Mette (Ulleval University Hospital (Norway)) ; Moreno, Santiago (Hospital Universitario Ramón y Cajal (Madrid)) ; Porter, Kholoud (University College London. Medical Research Council Clinical Trials Unit (United Kingdom)) ; Universitat Autònoma de Barcelona
Supplemental Digital Content is Available in the Text. Rapid CD4 cell loss represents an HIV phenotype used to identify causal variants of accelerated disease progression. The optimal rate and threshold for identifying this extreme phenotype in recently infected individuals is unclear. [...]
2014 - DOI (Digital Object Identifier)

10.1097/QAI.0000000000000240
Journal of acquired immune deficiency syndromes (1999), Vol. 67, Issue 1 (September 2014) , p. 15-21

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