Home > Search Results: Dos Santos, Helena G.
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24 p, 2.3 MB An Efficient Microarray-Based Genotyping Platform for the Identification of Drug-Resistance Mutations in Majority and Minority Subpopulations of HIV-1 Quasispecies / Martín, Verónica (Centro de Biología Molecular Severo Ochoa) ; Perales Viejo, Celia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Fernández-Algar, María (Centro de Astrobiología (Madrid)) ; Dos Santos, Helena G. (Centro de Biología Molecular Severo Ochoa) ; Garrido, Patricia (Biotherapix (Madrid)) ; Pernas, María (Biotherapix (Madrid)) ; Parro, Víctor (Centro de Astrobiología (Madrid)) ; Moreno, Miguel (Centro de Astrobiología (Madrid)) ; García-Pérez, Javier (Instituto de Salud Carlos III) ; Alcami, Jose (Instituto de Salud Carlos III) ; Torán, José Luis (Biotherapix (Madrid)) ; Abia, David (Centro de Biología Molecular Severo Ochoa) ; Domingo, Esteban (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ; Briones Llorente, Carlos (Centro de Astrobiología (Madrid)) ; Universitat Autònoma de Barcelona
The response of human immunodeficiency virus type 1 (HIV-1) quasispecies to antiretroviral therapy is influenced by the ensemble of mutants that composes the evolving population. Low-abundance subpopulations within HIV-1 quasispecies may determine the viral response to the administered drug combinations. [...]
2016 - 10.1371/journal.pone.0166902
PloS one, Vol. 11 (december 2016)  
Detailed record - Creative Commons

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