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21 p, 2.1 MB Natural Polymorphisms in Tap2 Influence Negative Selection and CD4:CD8 Lineage Commitment in the Rat / Tuncel, Jonatan (Karolinska Institutet. Department of Medical Biochemistry and Biophysics) ; Haag, Sabrina (Karolinska Institutet. Department of Medical Biochemistry and Biophysics) ; Yau, Anthony C. (Karolinska Institutet. Department of Medical Biochemistry and Biophysics) ; Norin, Ulrika (Karolinska Institutet. Department of Medical Biochemistry and Biophysics) ; Baud, Amelie (Wellcome Trust Centre for Human Genetics (Oxford, Regne Unit)) ; Lönnblom, Erik (Karolinska Institutet. Department of Medical Biochemistry and Biophysics) ; Maratou, Klio (Imperial College London) ; Ytterberg, A. Jimmy (Karolinska University Hospital) ; Ekman, Diana (Karolinska Institutet. Department of Medical Biochemistry and Biophysics) ; Thordardottir, Soley (Karolinska Institutet. Department of Medical Biochemistry and Biophysics) ; Johannesson, Martina (Karolinska Institutet. Department of Medical Biochemistry and Biophysics) ; Gillett, Alan (Karolinska University Hospital) ; Stridh, Pernilla (Karolinska University Hospital) ; Jagodic, Maja (Karolinska University Hospital) ; Olsson, Tomas (Karolinska University Hospital) ; Fernández-Teruel, Albert (Universitat Autònoma de Barcelona. Departament de Psiquiatria i Medicina Legal) ; Zubarev, Roman A. (Karolinska Institutet. Department of Medical Biochemistry and Biophysics) ; Mott, Richard (Wellcome Trust Centre for Human Genetics (Oxford, Regne Unit)) ; Aitman, Timothy J. (Imperial College London) ; Flint, Jonathan (Wellcome Trust Centre for Human Genetics (Oxford, Regne Unit)) ; Holmdahl, Rikard (Karolinska Institutet. Department of Medical Biochemistry and Biophysics) ; EURATRANS Consortium
Genetic variation in the major histocompatibility complex (MHC) affects CD4∶CD8 lineage commitment and MHC expression. However, the contribution of specific genes in this gene-dense region has not yet been resolved. [...]
2014 - 10.1371/journal.pgen.1004151
PLoS Genetics, Vol. 10 Issue 2 (February 2014) , p. e1004151  

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