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Articles, 2 records found
Articles 2 records found  
1.
20 p, 8.2 MB The small GTPase RAC1/CED-10 is essential in maintaining dopaminergic neuron function and survival against α-synuclein-induced toxicity / Kim, Hanna (University of Alabama. Department of Biological Sciences) ; Calatayud, Carles (Institut d'Investigació Biomèdica de Bellvitge) ; Guha, Sanjib (Buck Institute for Age Research) ; Fernández Carasa, Irene (Institut de Biomedicina de la Universitat de Barcelona) ; Berkowitz, Laura (University of Alabama. Department of Biological Sciences) ; Carballo Carbajal, Iria (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Ezquerra, Mario (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Fernández Santiago, Rubén (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Kapahi, Pankaj (Buck Institute for Age Research) ; Raya, Ángel (Institució Catalana de Recerca i Estudis Avançats) ; Miranda Vizuete, Antonio (Instituto de Biomedicina de Sevilla) ; Lizcano de Vega, José Miguel (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Vila Bover, Miquel (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Caldwell, Kim A. (University of Alabama. Department of Biological Sciences) ; Caldwell, Guy A. (University of Alabama. Department of Biological Sciences) ; Consiglio, Antonella (Università degli Studi di Brescia. Dipartimento di Medicina Molecolare e Traslazionale) ; Dalfo Capella, Esther (Universitat Autònoma de Barcelona. Departament de Biologia i Bioquímica Molecular)
Parkinson's disease is associated with intracellular α-synuclein accumulation and ventral midbrain dopaminergic neuronal death in the Substantia Nigra of brain patients. The Rho GTPase pathway, mainly linking surface receptors to the organization of the actin and microtubule cytoskeletons, has been suggested to participate to Parkinson's disease pathogenesis. [...]
2018 - 10.1007/s12035-018-0881-7
Molecular neurobiology, Vol. 55, issue 9 (Sep. 2018) , p. 7533-7552  
2.
18 p, 2.2 MB Aberrant epigenome in -derived dopaminergic neurons from Parkinson's disease patients / Fernández-Santiago, Rubén (Universitat de Barcelona) ; Carballo-Carbajal, Iria (Vall d'Hebron Institut de Recerca (VHIR)) ; Castellano, Giancarlo (Universitat de Barcelona. Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Torrent, Roger (Universitat de Barcelona. Institut de Biomedicina (IBUB)) ; Richaud, Yvonne (Biomaterials and Nanomedicine (CIBER-BBN). Centre for Networked Biomedical Research on Bioengineering) ; Sánchez-Danés, Adriana (Universitat de Barcelona. Institut de Biomedicina (IBUB)) ; Vilarrasa-Blasi, Roser (Universitat de Barcelona. Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Sánchez-Pla, Alex (Vall d'Hebron Institut de Recerca (VHIR)) ; Mosquera, José Luis (Universitat de Barcelona) ; Soriano, Jordi (Universitat de Barcelona) ; López-Barneo, José (Universidad de Sevilla. Hospital Universitario Virgen del Rocío.) ; Canals, Josep M (Universitat de Barcelona. Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Alberch i Vié, Jordi (Universitat de Barcelona. Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Raya, Ángel (Institució Catalana de Recerca i Estudis Avançats (ICREA)) ; Vila Bover, Miquel (Vall d'Hebron Institut de Recerca (VHIR)) ; Consiglio, Antonella (University of Brescia and National Institute of Neuroscience) ; Martín-Subero, José I (Universitat de Barcelona. Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Ezquerra, Mario (Universitat de Barcelona. Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Tolosa, Eduardo (Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED)) ; Universitat Autònoma de Barcelona
The epigenomic landscape of Parkinson's disease () remains unknown. We performed a genomewide methylation and a transcriptome studies in induced pluripotent stem cell ()-derived dopaminergic neurons (n) generated by cell reprogramming of somatic skin cells from patients with monogenic 2-associated (L2) or sporadic (), and healthy subjects. [...]
2015 - 10.15252/emmm.201505439
EMBO Molecular Medicine, Vol. 7, Núm. 12 (October 2015) , p. 1529-1546  

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3 Ezquerra, M.
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