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11 p, 1.6 MB Calcium Dobesilate Reverses Cognitive Deficits and Anxiety-Like Behaviors in the D-Galactose-Induced Aging Mouse Model through Modulation of Oxidative Stress / Hakimizadeh, Elham (Rafsanjan University of Medical Sciences. Physiology-Pharmacology Research Center) ; Zamanian, Mohammad (Hamadan University of Medical Sciences. School of Nahavand Paramedical) ; Gimenez-Llort, Lydia (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Sciorati, Clara (IRCCS Ospedale San Raffaele Scientific Institute. Division of Immunology, Transplantation and Infectious Diseases) ; Nikbakhtzadeh, Marjan (University of Medical Sciences. Department of Physiology) ; Kujawska, Małgorzata (Poznan University of Medical Sciences. Department of Toxicology) ; Kaeidi, Ayat (Rafsanjan University of Medical Sciences. Physiology-Pharmacology Research Center) ; Hassanshahi, Jalal (Rafsanjan University of Medical Sciences. Physiology-Pharmacology Research Center) ; Fatemi, Iman (Kerman University of Medical Sciences. Research Center of Tropical and Infectious Diseases) ; Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal
The long-term treatment of mice with D-galactose (D-gal) induces the overproduction of reactive oxygen species (ROS) and is a well-accepted experimental model of oxidative stress-linked cognitive disorders in physiological aging. [...]
2021 - 10.3390/antiox10050649
Antioxidants, Vol. 10 Núm. 5 (2021) , p. 649  
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