Results overview: Found 5 records in 0.02 seconds.
Articles, 3 records found
Research literature, 2 records found
Articles 3 records found  
1.
15 p, 517.3 KB GRECOS project (Genotyping Recurrence Risk of Stroke). The use of genetics to predict the vascular recurrence after stroke / Fernández Cadenas, Israel (Hospital Vall d'Hebron. Departament de Neurologia) ; Mendióroz, Maite (Hospital Vall d'Hebron. Departament de Neurologia) ; Giralt, Dolors (Hospital Vall d'Hebron. Departament de Neurologia) ; Nafria, Cristina (Hospital Vall d'Hebron. Departament de Neurologia) ; Garcia, Elena (Fundació Docència i Recerca Mutua Terrassa) ; Carrera, Caty (Hospital Vall d'Hebron Departament de Neurologia) ; Gallego-Fabrega, Cristina (Fundació Docència i Recerca Mutua Terrassa) ; Domingues-Montanari, Sophie (Hospital Vall d'Hebron. Departament de Neurologia) ; Delgado, Pilar (Hospital Vall d'Hebron. Departament de Neurologia) ; Ribó, Marc (Hospital Vall d'Hebron. Departament de Neurologia) ; Castellanos, Mar (Hospital Universitari Dr. Josep Trueta. Departament de Neurologia) ; Martínez, Sergi (Institut d'Investigació Biomèdica Sant Pau) ; Freijo, Mari Mar (Hospital de Basurto. Departamento de Neurologia) ; Jiménez-Conde, Jordi (Hospital del Mar. Departament de Neurologia) ; Rubiera, Marta (Hospital Vall d'Hebron. Departament de Neurologia) ; Alvarez Sabín, José (Hospital Vall d'Hebron. Departament de Neurologia) ; Molina, Carlos A. (Hospital Vall d'Hebron. Departament de Neurologia) ; Font, Maria Angels (Hospital de Bellvitge. Departament de Neurologia) ; Grau Olivares, Marta (Hospital Universitari Sagrat Cor. Departament de Neurologia) ; Palomeras, Ernest (Hospital de Mataró. Departament de Neurologia) ; Perez de la Ossa, Natalia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martinez Zabaleta, Maite (Hospital Donostia. Departamento de Neurologia) ; Masjuan, Jaime (Hospital Ramon y Cajal. Departamento de Neurologia) ; Moniche, Francisco (Hospital Universitario Virgen del Rocío. Departamento de Neurologia) ; Canovas, David (Corporació Sanitària Parc Taulí. Departament de Neurologia) ; Piñana, Carlos (Hospital Universitario Virgen de las Nieves. Departamento de Neurologia) ; Purroy, Francisco (Hospital Universitari Arnau de Vilanova. Departament de Neurologia) ; Cocho, Dolores (Hospital de Granollers. Departament de Neurologia) ; Navas, Inma (Hospital Mútua de Terrassa. Departament de Neurologia) ; Tejero, Carlos (Hospital Clínico Universitario Lozano Blesa. Departamento de Neurologia) ; Aymerich, Nuria (Hospital de Navarra. Departamento de Neurologia) ; Cullell, Natalia (Fundació Docència i Recerca Mutua Terrassa) ; Muiño, Elena (Fundació Docència i Recerca Mutua Terrassa) ; Serena, Joaquín (Hospital Universitari Dr. Josep Trueta. Departament de Neurologia) ; Rubio, Francisco (Hospital de Bellvitge. Departament de Neurologia) ; Davalos, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Roquer González, Jaume (Hospital del Mar. Departament de Neurologia) ; Arenillas Lara, Juan Francisco (Hospital Clínico Universitario de Valladolid. Departamento de Neurologia) ; Martí Fábregas, Joan (Institut d'Investigació Biomèdica Sant Pau) ; Keene, Keith (Center for Health Disparities. East Carolina University) ; Chen, Wei-Min (Department of Public Health Sciences; Center for Public Health Genomics, University of Virginia) ; Worrall, Bradford (Department of Neurology; Department of Public Health Sciences, University of Virginia) ; Sale, Michele (Center for Public Health Genomics, University of Virginia) ; Arboix, Adrià (Hospital Universitari Sagrat Cor. Departament de Neurologia) ; Krupinski, Jerzy (Hospital Mútua de Terrassa. Departament de Neurologia) ; Montaner, Joan (Hospital Vall d'Hebron. Departament de Neurologia) ; GRECOSstudy group ; Universitat Autònoma de Barcelona
Background and Purpose—Vascular recurrence occurs in 11% of patients during the first year after ischemic stroke (IS) or transient ischemic attack (TIA). Clinical scores do not predict the whole vascular recurrence risk, therefore we aimed to find genetic variants associated with recurrence that might improve the clinical predictive mode is in IS. [...]
2017 - 10.1161/STROKEAHA.116.014322
Stroke, Vol. 48 Núm. 5 (2017) , p. 1147-1153  
2.
5 p, 280.6 KB DNA Methylation in Stroke. Update of Latest Advances / Krupinski, Jerzy (School of Healthcare Science, Manchester Metropolitan University, Manchester, United Kingdom) ; Carrera, Caty (Neurovascular Research Laboratory, Institut de Recerca, Universitat Autònoma de Barcelona, Hospital Vall d'Hebron, Barcelona, Spain) ; Muiño, Elena (Stroke Pharmacogenomics and Genetics, Fundació Docència i Recerca Mutua Terrassa, Hospital Universitari Mútua de Terrassa, Terrassa, Barcelona, Spain) ; Torres, Nuria (Stroke Pharmacogenomics and Genetics, Fundació Docència i Recerca Mutua Terrassa, Hospital Universitari Mútua de Terrassa, Terrassa, Barcelona, Spain) ; Al-Baradie, Raid (Applied Medical Sciences College Majmaah University, Majmaah, Saudi Arabia) ; Cullell, Natalia (Stroke Pharmacogenomics and Genetics, Fundació Docència i Recerca Mutua Terrassa, Hospital Universitari Mútua de Terrassa, Terrassa, Barcelona, Spain) ; Fernandez-Cadenas, Israel (Institut d'Investigació Biomèdica Sant Pau)
Epigenetic modifications are hereditable and modifiable factors that do not alter the DNA sequence. These epigenetic factors include DNA methylation, acetylation of histones and non-coding RNAs. Epigenetic factors have mainly been associated with cancer but also with other diseases and conditions such as diabetes or obesity. [...]
2017 - 10.1016/j.csbj.2017.12.001
Computational and Structural Biotechnology Journal, Vol. 16 (december 2017) , p. 1-5  
3.
11 p, 168.8 KB Genetic variants in CETP increase risk of intracerebral hemorrhage / Anderson, Christopher D. (Program in Medical and Population Genetics, Broad Institute) ; Falcone, Guido J. (Departments of Epidemiology and Biostatistics, Harvard T. H. Chan School of Public Health) ; Phuah, Chia-Ling (Program in Medical and Population Genetics, Broad Institute) ; Radmanesh, Farid (Program in Medical and Population Genetics, Broad Institute) ; Brouwers, H. Bart (Program in Medical and Population Genetics, Broad Institute) ; Battey, Thomas W. K. (Program in Medical and Population Genetics, Broad Institute) ; Biffi, Alessandro (Division of Psychiatry, Department of Psychiatry, MGH) ; Peloso, Gina M. (Program in Medical and Population Genetics, Broad Institute) ; Liu, Dajiang J. (Institute of Personalized Medicine, Penn State College of Medicine) ; Ayres, Alison M. (J. Philip Kistler Stroke Research Center, Department of Neurology, MGH) ; Goldstein, Joshua N. (Department of Emergency Medicine, MGH) ; Viswanathan, Anand (J. Philip Kistler Stroke Research Center, Department of Neurology, MGH) ; Greenberg, Steven M. (J. Philip Kistler Stroke Research Center, Department of Neurology, MGH) ; Selim, Magdy (Beth Israel Deaconess Medical Center) ; Meschia, James F. (Mayo Clinic) ; Brown, Devin L. (University of Michigan Health System) ; Worrall, Bradford B. (University of Virginia Health System) ; Silliman, Scott L. (University of Florida College of Medicine) ; Tirschwell, David L. (University of Washington) ; Flaherty, Matthew L. (University of Cincinnati College of Medicine) ; Kraft, Peter (Departments of Epidemiology and Biostatistics, Harvard T. H. Chan School of Public Health) ; Jagiella, Jeremiasz M. (Jagiellonian University Medical College) ; Schmidt, Helena (Medical University Graz) ; Hansen, Björn M. (Skåne University Hospital) ; Jimenez-Conde, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ; Giralt-Steinhauer, Eva (Institut Hospital del Mar d'Investigacions Mèdiques) ; Elosua Llanos, Roberto (Institut Hospital del Mar d'Investigacions Mèdiques) ; Cuadrado-Godia, Elisa (Institut Hospital del Mar d'Investigacions Mèdiques) ; Soriano Tàrraga, Carolina (Institut Hospital del Mar d'Investigacions Mèdiques) ; van Nieuwenhuizen, Koen M. (University Medical Center Utrecht) ; Klijn, Catharina J. M. (Donders Institute for Brain, Cognition, and Behavior, Radboud University Medical Center) ; Rannikmae, Kristiina (University of Edinburgh) ; Samarasekera, Neshika (University of Edinburgh) ; Salman, Rustam Al-Shahi (University of Edinburgh) ; Sudlow, Catherine L. (University of Edinburgh) ; Deary, Ian J. (University of Edinburgh) ; Morotti, Andrea (Neurology Clinic, University of Brescia) ; Pezzini, Alessandro (Neurology Clinic, University of Brescia) ; Pera, Joanna (Jagiellonian University Medical College) ; Urbanik, Andrzej (Jagiellonian University Medical College) ; Pichler, Alexander (Medical University of Graz) ; Enzinger, Christian (Medical University of Graz) ; Norrving, Bo (Skåne University Hospital) ; Montaner, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Fernandez-Cadenas, Israel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Delgado Martínez, Pilar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Roquer González, Jaume (Institut Hospital del Mar d'Investigacions Mèdiques) ; Lindgren, Arne (Skåne University Hospital) ; Slowik, Agnieszka (Jagiellonian University Medical College) ; Schmidt, Reinhold (Medical University of Graz) ; Kidwell, Chelsea S. (University of Arizona) ; Kittner, Steven J. (Baltimore Veterans Administration Medical Center and University of Maryland School of Medicine) ; Waddy, Salina P. (National Institutes of Health) ; Langefeld, Carl D. (Wake Forest University) ; Abecasis, Goncalo (University of Michigan School of Public Health) ; Willer, Cristen J. (University of Michigan Medical School) ; Kathiresan, Sekar (Cardiovascular Disease Prevention Center, MGH) ; Woo, Daniel (University of Cincinnati College of Medicine) ; Rosand, Jonathan (Program in Medical and Population Genetics, Broad Institute) ; Universitat Autònoma de Barcelona. Departament de Neurologia
In observational epidemiologic studies, higher plasma high-density lipoprotein cholesterol (HDL-C) has been associated with increased risk of intracerebral hemorrhage (ICH). DNA sequence variants that decrease cholesteryl ester transfer protein (CETP) gene activity increase plasma HDL-C; as such, medicines that inhibit CETP and raise HDL-C are in clinical development. [...]
2016 - 10.1002/ana.24780
Annals of Neurology, Vol. 80 (october 2016) , p. 730-740  

Research literature 2 records found  
1.
366 p, 5.6 MB Genètica aplicada a la clínica neurovascular / Río Espínola, Alberto del, autor ; Fernández Cadenas, Israel, supervisor acadèmic ; Montaner, Joan, supervisor acadèmic ; Álvarez Sabín, J. (José), supervisor acadèmic ; Universitat Autònoma de Barcelona. Departament de Medicina
En aquesta tesi doctoral es descriuen els resultats de l'estudi farmacogenètic Geno-tPA, en el qual es va analitzar el paper de centenars de polimorfismes (SNPs) en la resposta al tractament trombolític de l'ictus isquèmic: recanalització arterial una hora després de la infusió, reoclusión arterial després d'haver recanalitzar, aparició de transformació hemorràgica iatrogènica i mortalitat intrahospitalària. [...]
This thesis describes the results of the Geno-tPA pharmacogenetic study, which analyzed the role of hundreds of polymorphisms (SNPs) in the response to thrombolytic treatmentof ischemic stroke: recanalization one hour after t-PA infusion, arterial reocclusion of the recanalized artery, presence of iatrogenic hemorrhagic transformation and in-hospital mortality. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2011  
2.
207 p, 5.4 MB Identificación y uso de biomarcadores pronósticos en el ictus isquémico / García Berrocoso, Teresa ; Montaner, Joan, dir. ; Fernández Cadenas, Israel, dir. ; Delgado Martínez, Pilar, dir. ; García Dorado, David ; Universitat Autònoma de Barcelona. Departament d'Antropologia Social i Cultural
El ictus es una enfermedad con una elevada morbimortalidad, suponiendo la segunda causa de muerte a nivel mundial y una de las principales causas de discapacidad en el adulto. Aun así, la heterogeneidad entre los pacientes con ictus dificulta anticipar el pronóstico de la enfermedad. [...]
Stroke is a severe disease, being the second cause of death worldwide and one of the main causes of disability. Heterogeneity among stroke patients makes difficult to anticipate the prognosis of the disease. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2014  

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