Results overview: Found 3 records in 8.39 seconds.
Articles, 3 records found
Articles 3 records found  
1.
11 p, 3.4 MB Low-dose statin treatment increases prostate cancer aggressiveness / Caro-Maldonado, Alfredo (CIC bioGUNE, Bizkaia Technology Park, Derio, Spain) ; Camacho, Laura (Biochemistry and Molecular Biology Department, University of the Basque Country, Bilbao, Spain) ; Zabala-Letona, Amaia (CIBERONC, Madrid, Spain) ; Torrano, Verónica (CIBERONC, Madrid, Spain) ; Fernández-Ruiz, Sonia (CIBERONC, Madrid, Spain) ; Zamacola-Bascaran, Kepa (CIC bioGUNE, Bizkaia Technology Park, Derio, Spain) ; Arreal, Leire (CIC bioGUNE, Bizkaia Technology Park, Derio, Spain) ; Valcárcel-Jiménez, Lorea (CIC bioGUNE, Bizkaia Technology Park, Derio, Spain) ; Martín-Martín, Natalia (CIBERONC, Madrid, Spain) ; Flores, Juana M. (Department of Animal Medicine and Surgery, School of Veterinary Medicine, Complutense University of Madrid, Madrid, Spain) ; Cortazar, Ana R. (CIC bioGUNE, Bizkaia Technology Park, Derio, Spain) ; Zúñiga-García, Patricia (CIC bioGUNE, Bizkaia Technology Park, Derio, Spain) ; Arruabarrena-Aristorena, Amaia (CIC bioGUNE, Bizkaia Technology Park, Derio, Spain) ; Guillaumond, Fabienne (Université Aix-Marseille, Marseille, France) ; Cabrera, Diana (CIC bioGUNE, Bizkaia Technology Park, Derio, Spain) ; Falcón-Perez, Juan M. (IKERBASQUE, Basque foundation for science, Bilbao, Spain) ; Aransay, Ana M. (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Madrid, Spain) ; Gomez-Muñoz, Antonio (Biochemistry and Molecular Biology Department, University of the Basque Country, Bilbao, Spain) ; Olivan, Mireia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Morote, Juan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Carracedo, Arkaitz (IKERBASQUE, Basque foundation for science, Bilbao, Spain) ; Universitat Autònoma de Barcelona
Prostate cancer is diagnosed late in life, when co-morbidities are frequent. Among them, hypertension, hypercholesterolemia, diabetes or metabolic syndrome exhibit an elevated incidence. In turn, prostate cancer patients frequently undergo chronic pharmacological treatments that could alter disease initiation, progression and therapy response. [...]
2017 - 10.18632/oncotarget.22217
Oncotarget, Vol. 9 (october 2017) , p. 1494-1504  
2.
39 p, 4.7 MB mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer / Zabala Letona, Amaia (CIBERONC) ; Arruabarrena Aristorena, Amaia (CIC bioGUNE) ; Martín Martín, Natalia (CIBERONC) ; Fernández Ruiz, Sonia (CIBERONC) ; Sutherland, James D. (CIC bioGUNE) ; Clasquin, Michelle (AGIOS Pharmaceuticals) ; Tomás Cortázar, Julen (CIC bioGUNE) ; Jiménez, José (Hospital Universitari Vall d'Hebron) ; Torres Ramírez, Inés Ma. de (Hospital Universitari Vall d'Hebron) ; Quang, Phong (AGIOS Pharmaceuticals) ; Ximénez Embun, Pilar (Spanish National Cancer Research Centre) ; Bago, Ruzica (MRC Protein Phosphorylation and Ubiquitylation Unit) ; Ugalde Olano, Aitziber (Basurto University Hospital) ; Loizaga Iriarte, Ana (Basurto University Hospital) ; Lacasa Viscasillas, Isabel (Basurto University Hospital) ; Unda, Miguel (Basurto University Hospital) ; Torrano, Verónica (CIBERONC) ; Cabrera, Diana (CIC bioGUNE) ; van Liempd, Sebastiaan M. (CIC bioGUNE) ; Cendon, Ylenia (Universidad Autónoma de Madrid) ; Castro, Elena (Spanish National Cancer Research Centre) ; Murray, Stuart (AGIOS Pharmaceuticals) ; Revandkar, Ajinkya (University of Lausanne) ; Alimonti, Andrea (University of Lausanne) ; Zhang, Yinan (Harvard School of Public Health) ; Barnett, Amelia (AGIOS Pharmaceuticals) ; Lein, Gina (AGIOS Pharmaceuticals) ; Pirman, David (AGIOS Pharmaceuticals) ; Cortázar, Ana R. (CIC bioGUNE) ; Arreal, Leire (CIC bioGUNE) ; Prudkin, Ludmila (Hospital Universitari Vall d'Hebron) ; Astobiza, Ianire (CIC bioGUNE) ; Valcárcel Jiménez, Lorea (CIC bioGUNE) ; Zúñiga García, Patricia (CIC bioGUNE) ; Fernández Domínguez, Itziar (CIC bioGUNE) ; Piva, Marco (CIC bioGUNE) ; Caro Maldonado, Alfredo (CIC bioGUNE) ; Sánchez Mosquera, Pilar (CIC bioGUNE) ; Castillo Martín, Mireia (Fundação Champalimaud) ; Serra, Violeta (Hospital Universitari Vall d'Hebron) ; Beraza, Naiara (CIC bioGUNE) ; Gentilella, Antonio (Catalan Institute of Oncology) ; Thomas, George (Catalan Institute of Oncology) ; Azkargorta, Mikel (Carlos III Networked Proteomics Platform) ; Elortza, Felix (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ; Farràs, Rosa (Centro de Investigación Príncipe Felipe) ; Olmos, David (Hospitales Universitarios Virgen de la Victoria y Regional de Málaga) ; Efeyan, Alejo (Spanish National Cancer Research Centre) ; Anguita, Juan (Ikerbasque) ; Muñoz, Javier (Carlos III Networked Proteomics Platform) ; Falcón Pérez, Juan M. (Ikerbasque) ; Barrio, Rosa (CIC bioGUNE) ; Macarulla Mercadé, Teresa (Hospital Universitari Vall d'Hebron) ; Mato, José M. (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ; Martínez Chantar, Maria L. (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ; Cordon Cardo, Carlos (Icahn School of Medicine at Mount Sinai) ; Aransay, Ana M. (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ; Marks, Kevin (AGIOS Pharmaceuticals) ; Baselga Torres, Josep, 1959-, (Memorial Sloan-Kettering Cancer Center) ; Tabernero Caturla, Josep (Hospital Universitari Vall d'Hebron) ; Nuciforo, Paolo (Hospital Universitari Vall d'Hebron) ; Manning, Brendan D. (Harvard School of Public Health) ; Marjon, Katya (AGIOS Pharmaceuticals) ; Carracedo, Arkaitz (University of the Basque Country) ; Universitat Autònoma de Barcelona
Activation of the PTEN-PI3K-mTORC1 pathway consolidates metabolic programs that sustain cancer cell growth and proliferation,. Here we show that mTORC1 regulates polyamine dynamics, a metabolic route that is essential for oncogenicity. [...]
2017 - 10.1038/nature22964
Nature, Vol. 547 (July 2017) , p. 109-113  
3.
17 p, 4.2 MB RARRES3 suppresses breast cancer lung metastasis by regulating adhesion and differentiation / Morales, Mònica (Institut de Recerca Biomèdica) ; Arenas, Enrique J (Institut de Recerca Biomèdica) ; Urosevic, Jelena (Institut de Recerca Biomèdica) ; Guiu, Marc (Institut de Recerca Biomèdica) ; Fernández, Esther (Institut de Recerca Biomèdica) ; Planet, Evarist (Institut de Recerca Biomèdica) ; Fenwick, Robert Bryn (Institut de Recerca Biomèdica) ; Fernández Ruiz, Sonia (CIC bioGUNE) ; Salvatella, Xavier (Institut de Recerca Biomèdica) ; Reverter i Cendrós, David (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Carracedo, Arkaitz (CIC bioGUNE) ; Massagué, Joan (Howard Hughes Medical Institute (Maryland, Estats Units d'Amèrica)) ; Gomis, Roger R (Institució Catalana de Recerca i Estudis Avançats) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular
In estrogen receptor-negative breast cancer patients, metastatic relapse usually occurs in the lung and is responsible for the fatal outcome of the disease. Thus, a better understanding of the biology of metastasis is needed. [...]
2014 - 10.15252/emmm.201303675
EMBO Molecular Medicine, Vol. 6, issue 7 (Jul. 2014) , p. 865-881  

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