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Articles, 2 records found
Articles 2 records found  
1.
6 p, 346.3 KB Topical treatment with brimonidine and somatostatin causes retinal vascular dilation in patients with early diabetic retinopathy from the EUROCONDOR / Grauslund, Jakop (Odense University Hospital (Dinamarca)) ; Frydkjaer-Olsen, Ulrik (Department of Clinical Research. University of Southern Denmark) ; Peto, Tunde (Centre for Public Health. Institute of Clinical Sciences. Queen's University Belfast) ; Fernández-Carneado, Jimena (BCN Peptides) ; Ponsati, Berta (BCN Peptides) ; Hernández, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Cunha-Vaz, José (Association for Innovation and Biomedical Research on Light and Image (AIBILI). University of Coimbra) ; Simó Canonge, Rafael (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
PURPOSE. Structural retinal microvascular changes have been identified as risk markers of diabetic retinopathy (DR). In order to estimate the retinal response of neuroprotective eye drops, we aimed to evaluate the effect of topical retinal neuroprotection on retinal microvascular changes in early DR. [...]
2019 - 10.1167/iovs.18-26487
Investigative Ophthalmology & Visual Science, Vol. 60 Núm. 6 (may 2019) , p. 2257-2262  
Detailed record - Creative Commons
2.
10 p, 1.6 MB Topical Administration of Somatostatin Prevents Retinal Neurodegeneration in Experimental Diabetes / Hernández, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Garcia-Ramírez, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Corraliza Márquez, Lidia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Fernández-Carneado, Jimena (BCN Peptides, Barcelona, Spain) ; Farrera-Sinfreu, Josep (BCN Peptides, Barcelona, Spain) ; Ponsati, Berta (BCN Peptides, Barcelona, Spain) ; González-Rodríguez, Águeda (Instituto de Investigaciones Biomédicas "Alberto Sols") ; Valverde, Ángela M. (Instituto de Investigaciones Biomédicas "Alberto Sols") ; Simó Canonge, Rafael (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Retinal neurodegeneration is an early event in the pathogenesis of diabetic retinopathy (DR). Somatostatin (SST) is an endogenous neuroprotective peptide that is downregulated in the diabetic eye. The aim of the study was to test the usefulness of topical administration of SST in preventing retinal neurodegeneration. [...]
2013 - 10.2337/db12-0926
Diabetes, Vol. 62 (june 2013) , p. 2569-2578  
Detailed record - Creative Commons

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