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Welfare Impact of Carbon Dioxide Euthanasia on Laboratory Mice and Rats : A Systematic Review
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Turner, Patricia V. (Global Animal Welfare and Training) ;
Hickman, Debra L. (Indiana University. Laboratory Animal Resource Center) ;
van Luijk, Judith (Radboud University. Department of Health Evidence) ;
Ritskes-Hoitinga, Merel (Radboud University. Department of Health Evidence) ;
Sargeant, Jan M. (University of Guelph. Centre for Public Health and Zoonoses) ;
Kurosawa, T. Miki (Kagoshima University. Faculty of Veterinary Medicine) ;
Agui, Takashi (Hokkaido University. Department of Applied Veterinary Science) ;
Baumans, Vera (Department of Animals, Science and Society, Utrecht University) ;
Choi, Woo Sung (National New Drug Development Cluster) ;
Choi, Yang-Kyu (Konkuk University. Department of Laboratory Animal Medicine) ;
Flecknell, Paul A. (Newcastle University. Institute of Neuroscience) ;
Lee, Byeong H. (Osong Medical Innovation Foundation) ;
Otaegui Goya, Pedro José (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Pritchett-Corning, Kathleen R. (University of Washington. Department of Comparative Medicine) ;
Shimada, Keisuke (Osaka University. Animal Resource Center for Infectious Diseases)
Background: There has been increased concern about the suitability of CO as a method for euthanasia of laboratory mice and rats, including the potential discomfort, pain or distress that animals may experience prior to loss of consciousness; time to loss of consciousness; best methods for use of CO; and the availability of better alternatives. [...]
2020 -  10.3389/fvets.2020.00411
Frontiers in Veterinary Science, Vol. 7 (july 2020)
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The IMPROVE Guidelines (Ischaemia Models : Procedural Refinements Of in Vivo Experiments)
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Percie du Sert, Nathalie (National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs), London, UK) ;
Alfieri, Alessio (The Roslin Institute and R(D)SVS, University of Edinburgh, Easter Bush, Midlothian, UK) ;
Allan, Stuart M. (Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK) ;
Carswell, Hilary V. O. (Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), University of Strathclyde, Glasgow, UK) ;
Deuchar, Graeme A. (Institute of Neuroscience and Psychology, College of Medical, Veterinary and Life Sciences, University of Glasgow/Arum Biosciences, Glasgow, UK) ;
Farr, Tracy D. (School of Life Sciences, University of Nottingham Medical School, Nottingham, UK) ;
Flecknell, Paul (Comparative Biology Centre, Newcastle University, UK) ;
Gallagher, Lindsay (Institute of Neuroscience and Psychology, College of Medical, Veterinary and Life Sciences, University of Glasgow/Arum Biosciences, Glasgow, UK) ;
Gibson, Claire L. (Department of Neuroscience, Psychology and Behaviour, University of Leicester, Leicester, UK) ;
Haley, Michael J. (Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK) ;
Macleod, Malcolm R. (Centre for Clinical Brain Sciences. University of Edinburgh) ;
McColl, Barry W. (The Roslin Institute and R(D)SVS, University of Edinburgh, Easter Bush, Midlothian, UK) ;
McCabe, Christopher (Institute of Neuroscience and Psychology, College of Medical, Veterinary and Life Sciences, University of Glasgow/Arum Biosciences, Glasgow, UK) ;
Morancho, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Moon, Lawrence D. F. (King's College London. Wolfson Centre for Age-Related Diseases) ;
O'Neill, Michael J. (Eli Lilly and Co., Windlesham, Surrey, UK) ;
Pérez de Puig, Isabel (Institut d'Investigacions Biomèdiques de Barcelona) ;
Planas, Anna Maria (Institut d'Investigacions Biomèdiques de Barcelona) ;
Ragan, C. Ian (NC3Rs Board, London, UK) ;
Rosell Novel, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Roy, Lisa A. (Institute of Neuroscience and Psychology, College of Medical, Veterinary and Life Sciences, University of Glasgow/Arum Biosciences, Glasgow, UK) ;
Ryder, Kathryn O. (Home Office, London, UK) ;
Simats Oriol, Alba (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Sena, Emily S. (Centre for Clinical Brain Sciences. University of Edinburgh) ;
Sutherland, Brad A. (School of Medicine, Faculty of Health, University of Tasmania, Hobart, Australia) ;
Tricklebank, Mark D. (King's College London) ;
Trueman, Rebecca C. (School of Life Sciences, University of Nottingham Medical School, Nottingham, UK) ;
Whitfield, Lucy (University of London. Royal Veterinary College (Hatfield, Regne Unit)) ;
Wong, Raymond (Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK) ;
Macrae, I Mhairi (Institute of Neuroscience and Psychology, College of Medical, Veterinary and Life Sciences, University of Glasgow/Arum Biosciences, Glasgow, UK) ;
Universitat Autònoma de Barcelona
Most in vivo models of ischaemic stroke target the middle cerebral artery and a spectrum of stroke severities, from mild to substantial, can be achieved. This review describes opportunities to improve the in vivo modelling of ischaemic stroke and animal welfare. [...]
2017 - 10.1177/0271678X17709185
Journal of Cerebral Blood Flow & Metabolism, Vol. 37 (august 2017) , p. 3488-3517
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