Home > Search Results: Florindo, Helena F.
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1.9 MB AKT2 siRNA delivery with amphiphilic-based polymeric micelles show efficacy against cancer stem cells / Rafael, Diana (Universitat Autònoma de Barcelona) ; Gener, Petra (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Andrade, Fernanda (Instituto de Salud Carlos III) ; Seras-Franzoso, Joaquin (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Montero, Sara (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Fernández Caparrós, Yolanda (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Hidalgo, Manuel (Rosenberg Clinical Cancer Center Beth Israel Deaconess Medical Center) ; Arango, Diego (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Florindo, Helena F. (Universidade de Lisboa) ; Abasolo, Ibane (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Schwartz, Simon (Instituto de Salud Carlos III) ; Videira, Mafalda (Universidade de Lisboa) ; Universitat Autònoma de Barcelona
Development of RNA interference-based therapies with appropriate therapeutic window remains a challenge for advanced cancers. Because cancer stem cells (CSC) are responsible of sustaining the metastatic spread of the disease to distal organs and the progressive gain of resistance of advanced cancers, new anticancer therapies should be validated specifically for this subpopulation of cells. [...]
2018 - 10.1080/10717544.2018.1461276
Drug Delivery, Vol. 25 (april 2018) , p. 961-972  
Detailed record - Creative Commons

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