Results overview: Found 3 records in 0.02 seconds.
Articles, 3 records found
Articles 3 records found  
1.
15 p, 11.4 MB Neuroprotective drug for nerve trauma revealed using artificial intelligence. / Romeo Guitart, David (Universitat Autónoma de Barcelona. Institut de Neruorciències) ; Forés, Joaquim (Hospital Clínic i Provincial.Unitat del Sistema Nervioso Periférico) ; Herrando-Grabulosa, Mireia (Universitat Autònoma de Barcelona. Insitut de Neurociències) ; Valls, Raquel (Anaxomics Biotech.) ; Leiva Rodríguez, Tatiana (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Galea, Elena (Universitat Autònoma de Barcelona. Institut de Neurociències) ; González-Pérez, Francisco (Universitat Autònoma de Barcelona. Institut de Neruociències) ; Navarro, Xavier. (Xavier) (Universitat Autònoma de Barcelona. Institut de Neruociències) ; Petegnief, Valerie (Institut de Recerca Biomèdica de Barcelona(IBB)) ; Bosch i Merino, Assumpció (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Coma, Mireia (Anaxomics Biotech.) ; Mas, José Manuel (Anaxomics Biotech.) ; Casas Louzao, Caty (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Here we used a systems biology approach and artifcial intelligence to identify a neuroprotective agent for the treatment of peripheral nerve root avulsion. Based on accumulated knowledge of the neurodegenerative and neuroprotective processes that occur in motoneurons after root avulsion, we built up protein networks and converted them into mathematical models. [...]
2018 - 10.1038/s41598-018-19767-3
Scientific reports, Vol. 8 (2018) , art. 1879  
2.
12 p, 7.4 MB Boosted Regeneration and Reduced Denervated Muscle Atrophy by NeuroHeal in a Pre-clinical Model of Lumbar Root Avulsion with Delayed Reimplantation / Romeo Guitart, David (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Forés Vineta, Joaquim (Universitat de Barcelona. Hospital Clínic) ; Navarro, Xavier. (Xavier) (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Casas Louzao, Caty (Universitat Autònoma de Barcelona. Institut de Neurociències)
The "gold standard" treatment of patients with spinal root injuries consists of delayed surgical reconnection of nerves. The sooner, the better, but problems such as injury-induced motor neuronal death and muscle atrophy due to long-term denervation mean that normal movement is not restored. [...]
2017 - 10.1038/s41598-017-11086-3
Scientific reports, Vol. 7 (2017) , art. 12028  
3.
13 p, 3.4 MB Network-based proteomic approaches reveal the neurodegenerative, neuroprotective and pain-related mechanisms involved after retrograde axonal damage / Casas Louzao, Caty (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Isus, Laura (Institut de Recerca Biomèdica) ; Herrando-Grabulosa, Mireia (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Mancuso, Francesco M. (Vall d'Hebron Institut d'Oncologia) ; Borrás, Eva (Universitat Pompeu Fabra. Centre de Regulació Genòmica) ; Sabidó, Eduardo (Universitat Pompeu Fabra. Centre de Regulació Genòmica) ; Forés Vineta, Joaquim (Universitat de Barcelona. Hospital Clínic) ; Aloy, Patrick (Institució Catalana de Recerca i Estudis Avançats (ICREA))
Neurodegenerative processes are preceded by neuronal dysfunction and synaptic disconnection. Disconnection between spinal motoneuron (MN) soma and synaptic target leads either to a retrograde degenerative process or to a regenerative reaction, depending injury proximity among other factors. [...]
2015 - 10.1038/srep09185
Scientific reports, Vol. 5 (2015) , art. 9185  

See also: similar author names
2 Fores, J.
2 Forés, J.
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