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Articles, 4 records found
Articles 4 records found  
1.
11 p, 1.2 MB Antidepressant use in Denmark, Germany, Spain, and Sweden between 2009 and 2014 : Incidence and comorbidities of antidepressant initiators / Forns, Joan (RTI Health Solutions. Epidemiology) ; Pottegård, Anton (Clinical Pharmacology and Pharmacy. Department of Public Health. University of Southern Denmark) ; Reinders, Tammo (Leibniz Institute for Prevention Research and Epidemiology-BIPS) ; Poblador-Plou, Beatriz (Instituto de Investigación Sanitaria de Aragón) ; Morros, Rosa (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Brandt, Lena (Centre for Pharmacoepidemiology. Department of Medicine. Solna. Karolinska Institutet. Karolinska University Hospital) ; Cainzos-Achirica, Miguel (Epidemiology. RTI Health Solutions) ; Hellfritzsch, Maja (Clinical Pharmacology and Pharmacy. Department of Public Health. University of Southern Denmark) ; Schink, Tania (Leibniz Institute for Prevention Research and Epidemiology-BIPS) ; Prados-Torres, Alexandra (Instituto de Investigación Sanitaria de Aragón) ; Giner-Soriano, Maria (Institut Català de la Salut) ; Hägg, David (Centre for Pharmacoepidemiology. Department of Medicine. Solna. Karolinska Institutet. Karolinska University Hospital) ; Hallas, Jesper (Clinical Pharmacology and Pharmacy. Department of Public Health. University of Southern Denmark) ; Cortés, Jordi (Universitat Politècnica de Catalunya. Departament d'Estadística i Investigació Operativa) ; Jacquot, Emmanuelle (Pharmacoepidemiology Department. Les Laboratoires Servier) ; Deltour, Nicolas (Pharmacoepidemiology Department. Les Laboratoires Servier) ; Perez-Gutthann, S. (Epidemiology. RTI Health Solutions) ; Pladevall-Vila, Manel (Epidemiology. RTI Health Solutions) ; Reutfors, Johan (Centre for Pharmacoepidemiology. Department of Medicine. Solna. Karolinska Institutet. Karolinska University Hospital)
Background: We aimed to describe patterns of use and characteristics of 10 commonly used antidepressants for the period 2009-2014 in Denmark, Germany, Spain, and Sweden. Methods: Adult initiators from 2009 to 2014 of each study antidepressant were identified in four countries using five data sources: the Danish National registers, GePaRD (Germany), EpiChron (Aragon, Spain), SIDIAP (Catalonia, Spain), and the Swedish National Registers. [...]
2019 - 10.1016/j.jad.2019.02.010
Journal of Affective Disorders, Vol. 249 (April 2019) , p. 242-252  
2.
13 p, 786.0 KB Risk of Acute Liver Injury in Agomelatine and Other Antidepressant Users in Four European Countries : A Cohort and Nested Case-Control Study Using Automated Health Data Sources / Pladevall-Vila, Manel (Epidemiology. RTI Health Solutions) ; Pottegård, Anton (Clinical Pharmacology and Pharmacy. Department of Public Health. University of Southern Denmark) ; Schink, Tania (Leibniz Institute for Prevention Research and Epidemiology-BIPS) ; Reutfors, Johan (Centre for Pharmacoepidemiology. Department of Medicine. Solna. Karolinska Institutet. Karolinska University Hospital) ; Morros, Rosa. (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Poblador-Plou, Beatriz (Instituto de Investigación Sanitaria de Aragón) ; Timmer, Antje (Division of Epidemiology and Biometry. Medical Faculty. Carl von Ossietzky University) ; Forns, Joan (Epidemiology. RTI Health Solutions) ; Hellfritzsch, Maja (Clinical Pharmacology and Pharmacy. Department of Public Health. University of Southern Denmark) ; Reinders, Tammo (Leibniz Institute for Prevention Research and Epidemiology-BIPS) ; Hägg, David (Centre for Pharmacoepidemiology. Department of Medicine. Solna. Karolinska Institutet. Karolinska University Hospital) ; Giner-Soriano, Maria (Institut Català de la Salut) ; Prados-Torres, Alexandra (Instituto de Investigación Sanitaria de Aragón) ; Cainzos-Achirica, Miguel (Epidemiology. RTI Health Solutions) ; Hallas, Jesper (Clinical Pharmacology and Pharmacy. Department of Public Health. University of Southern Denmark) ; Brandt, Lena (Centre for Pharmacoepidemiology. Department of Medicine. Solna. Karolinska Institutet. Karolinska University Hospital) ; Cortés, Jordi (Universitat Politècnica de Catalunya. Departament d'Estadística i Investigació Operativa) ; Aguado, Jaume (Epidemiology. RTI Health Solutions) ; Perlemuter, Gabriel (INSERM U996) ; Falissard, Bruno (CESP INSERM U1018. Université Paris-Saclay. Université Paris-Sud. UVSQ. APHP) ; Castellsague, Jordi (Epidemiology. RTI Health Solutions) ; Jacquot, Emmanuelle (Pharmacoepidemiology Department. Servier) ; Deltour, Nicolas (Pharmacoepidemiology Department. Servier) ; Perez-Gutthann, S. (Epidemiology. RTI Health Solutions)
Background: Agomelatine is a melatonin receptor agonist and serotonin 5-HT receptor antagonist indicated for depression in adults. Hepatotoxic reactions like acute liver injury (ALI) are an identified risk in the European risk management plan for agomelatine. [...]
2019 - 10.1007/s40263-019-00611-9
CNS Drugs, Vol. 33 Núm. 4 (april 2019) , p. 383-395  
3.
11 p, 536.7 KB Validity of ICD-9 and ICD-10 codes used to identify acute liver injury : A study in three European data sources / Forns, Joan (RTI Health Solutions) ; Cainzos-Achirica, Miguel (RTI Health Solutions) ; Hellfritzsch, Maja (Clinical Pharmacology and Pharmacy. Department of Public Health. University of Southern Denmark) ; Morros, Rosa (Universitat Autònoma de Barcelona) ; Poblador-Plou, Beatriz (Instituto de Investigación Sanitaria de Aragón) ; Hallas, Jesper (Clinical Pharmacology and Pharmacy. Department of Public Health. University of Southern Denmark) ; Giner-Soriano, Maria (Universitat Autònoma de Barcelona) ; Prados-Torres, Alexandra (Instituto de Investigación Sanitaria de Aragón) ; Pottegård, Anton (Clinical Pharmacology and Pharmacy. Department of Public Health. University of Southern Denmark) ; Cortés, Jordi (Universitat Politècnica de Catalunya. Departament d'Estadística i Investigació Operativa) ; Castellsague, Jordi (RTI Health Solutions) ; Jacquot, Emmanuelle (Pharmacoepidemiology Department. Les Laboratoires Servier) ; Deltour, Nicolas (Pharmacoepidemiology Department. Les Laboratoires Servier) ; Perez-Gutthann, S. (RTI Health Solutions) ; Pladevall-Vila, Manel (RTI Health Solutions)
Purpose: Validating cases of acute liver injury (ALI) in health care data sources is challenging. Previous validation studies reported low positive predictive values (PPVs). Methods: Case validation was undertaken in a study conducted from 2009 to 2014 assessing the risk of ALI in antidepressants users in databases in Spain (EpiChron and SIDIAP) and the Danish National Health Registers. [...]
2019 - 10.1002/pds.4803
Pharmacoepidemiology and Drug Safety, Vol. 28 Núm. 7 (july 2019) , p. 965-975  
4.
13 p, 1.3 MB Airborne copper exposure in school environments associated with poorer motor performance and altered basal ganglia / Pujol Nuez, Jesús (Centro de Investigación Biomédica en Red de Salud Mental) ; Fenoll, Raquel (Hospital del Mar (Barcelona, Catalunya)) ; Macià Bros, Dídac (Hospital del Mar (Barcelona, Catalunya)) ; Martínez Vilavella, Gerard (Hospital del Mar (Barcelona, Catalunya)) ; Álvarez Pedrerol, Mar (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ; Rivas Lara, Ioar (Institut de Diagnosi Ambiental i Estudis de l'Aigua) ; Forns, Joan (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ; Deus Yela, Juan (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ; Blanco Hinojo, Laura (Hospital del Mar (Barcelona, Catalunya)) ; Querol Carceller, Xavier (Institut de Diagnosi Ambiental i Estudis de l'Aigua) ; Sunyer Deu, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques)
Children are more vulnerable to the effects of environmental elements. A variety of air pollutants are among the identified factors causing neural damage at toxic concentrations. It is not obvious, however, to what extent the tolerated high levels of air pollutants are able to alter brain development. [...]
2016 - 10.1002/brb3.467
Brain and behavior, Vol. 6, Issue 6 (June 2016) , art. e00467  

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