Resultats globals: 8 registres trobats en 0.01 segons.
Articles, 7 registres trobats
Documents de recerca, 1 registres trobats
Articles 7 registres trobats  
1.
32 p, 2.8 MB Beneficial effects of IL-37 after spinal cord injury in mice / Coll Miró, Marina (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Francos Quijorna, Isaac (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Santos Nogueira, Eva (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Torres Espín, Abel (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Bufler, P. (Ludwig-Maximilians-Universität München. Department of Pediatrics) ; Dinarello, CA. (Radboud University Medical Center. Department of Medicine) ; López Vales, Rubén (Universitat Autònoma de Barcelona. Institut de Neurociències)
IL-37, a member of the IL-1 family, broadly reduces innate inflammation as well as acquired immunity. Whether the antiinflammatory properties of IL-37 extend to the central nervous system remains unknown, however. [...]
2016 - 10.1073/pnas.1523212113
Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, issue 5 (2016) , p. 1411-1416  
2.
13 p, 3.3 MB Maresin 1 promotes inflammatory resolution, neuroprotection, and functional neurological recovery after Spinal Cord Injury / Francos Quijorna, Isaac (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Santos Nogueira, Eva (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Gronert, Karsten (University of California (Berkeley)) ; Sullivan, Aaron B. (University of California (Berkeley)) ; Kopp, Marcel A. (Charité-Universitätsmedizin Berlin (Berlin, Alemanya)) ; Brommer, Benedikt (Charité-Universitätsmedizin Berlin (Berlin, Alemanya)) ; David, Samuel (McGill University Health Centre (Montreal, Canadà)) ; Schwab, Jan M. (Charité-Universitätsmedizin Berlin (Berlin, Alemanya)) ; López Vales, Rubén (Universitat Autònoma de Barcelona. Institut de Neurociències)
Resolution of inflammation is defective after spinal cord injury (SCI), which impairs tissue integrity and remodeling and leads to functional deficits. Effective pharmacological treatments for SCI are not currently available. [...]
2017 - 10.1523/JNEUROSCI.1395-17.2017
The Journal of Neuroscience, Vol. 37, Núm. 48 (November 2017) , p. 11731-11743  
3.
30 p, 219.1 KB IL-4 drives microglia and macrophages toward a phenotype conducive for tissue repair and functional recovery after spinal cord injury / Francos Quijorna, Isaac (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Amo Aparicio, Jesús (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Martínez Muriana, Anna (Universitat Autònoma de Barcelona. Institut de Neurociències) ; López Vales, Rubén (Universitat Autònoma de Barcelona. Institut de Neurociències)
Macrophages and microglia play a key role in the maintenance of nervous system homeostasis. However, upon different challenges, they can adopt several phenotypes, which may lead to divergent effects on tissue repair. [...]
2016 - 10.1002/glia.23041
Glia, Vol. 64 Núm. 12 (2016) , p. 2079-2092
9 documents
4.
13 p, 2.2 MB CSF1R blockade slows the progression of amyotrophic lateral sclerosis by reducing microgliosis and invasion of macrophages into peripheral nerves / Martínez Muriana, Anna (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Mancuso, Renzo (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Francos Quijorna, Isaac (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Olmos Alonso, Adrian (University of Southampton. Centre for Biological Sciences) ; Osta, Rosario (Universidad de Zaragoza) ; Perry, V. Hugh (University of Southampton. Centre for Biological Sciences) ; Navarro, X. (Xavier) (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Gomez-Nicola, Diego (University of Southampton. Centre for Biological Sciences) ; López Vales, Rubén (Universitat Autònoma de Barcelona. Institut de Neurociències)
Inflammation is a common neuropathological feature in several neurological disorders, including amyotrophic lateral sclerosis (ALS). We have studied the contribution of CSF1R signalling to inflammation in ALS, as a pathway previously reported to control the expansion and activation of microglial cells. [...]
2016 - 10.1038/srep25663
Scientific Reports, Vol. 6 (May 2016) , article 25663  
5.
15 p, 2.1 MB CD300f immunoreceptor contributes to peripheral nerve regeneration by the modulation of macrophage inflammatory phenotype. / Peluffo, Hugo (Institut Pasteur de Montevideo. Laboratorio de Neuroinflamación y Terapia Génica) ; Solari-Saquieres, Patricia (Institut Pasteur de Montevideo. Laboratorio de Neuroinflamación y Terapia Génica) ; Negro-Demontel, María Luciana (Institut Pasteur de Montevideo. Laboratorio de Neuroinflamación y Terapia Génica) ; Francos Quijorna, Isaac (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Navarro, X. (Xavier) (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; López Vales, Rubén (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Sayós, Joan (Vall d'Hebron Institut de Recerca) ; Lago, Natalia (Institut Pasteur de Montevideo. Laboratorio de Neuroinflamación y Terapia Génica)
Background: It has recently become evident that activating/inhibitory cell surface immune receptors play a critical role in regulating immune and inflammatory processes in the central nervous system (CNS). [...]
2015 - 10.1186/s12974-015-0364-y
Journal of neuroinflammation, Vol. 12, No. 145 (2015)  
6.
11 p, 3.3 MB Differential effects on KCC2 expression and spasticity of ALS and traumatic injuries to motoneurons / Mòdol, Laura (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Mancuso, Renzo (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Alé, Albert (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Francos Quijorna, Isaac (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Navarro, X. (Xavier) (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease manifested by progressive muscle atrophy and paralysis due to the loss of upper and lower motoneurons (MN). Spasticity appears in ALS patients leading to further disabling consequences. [...]
2014 - 10.3389/fncel.2014.00007
Frontiers in cellular neuroscience, Vol. 8 Núm. 7 (Jan. 2014) , p. 1-11  
7.
11 p, 4.1 MB Beneficial effects of αB-crystallin in spinal cord contusion injury / Klopstein, Armelle (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Santos Nogueira, Eva (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Francos Quijorna, Isaac (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Redensek, Adriana (McGill University Health Centre. Center for Research in Neuroscience) ; David, Samuel (McGill University Health Centre. Center for Research in Neuroscience) ; Navarro, X. (Xavier) (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; López Vales, Rubén (Universitat Autònoma de Barcelona. Institut de Neurociències)
αB-crystallin is a member of the heat shock protein family that exerts cell protection under several stress-related conditions. Recent studies have revealed that αB-crystallin plays a beneficial role in a mouse model of multiple sclerosis, brain ischemia, and Alexander disease. [...]
2012 - 10.1523/JNEUROSCI.0923-12.2012
The Journal of neuroscience, Vol. 32 No. 42 (October 2012) , p. 14478-14488  

Documents de recerca 1 registres trobats  
1.
256 p, 5.8 MB Activation of inflammatory resolution programs as a new therapeutic approach to promote neuroprotectin after SCI / Francos Quijorna, Isaac ; López Vales, Rubén, dir. ; Universitat Autònoma de Barcelona. Institut de Neurociències
La respuesta inflamatoria juega un papel esencial protegiendo el cuerpo después de lesión o invasión por microorganismos, tales como bacterias y parásitos. Sin embargo, la inflamación debe ser un proceso altamente regulado, de lo contrario, puede conducir a daños en los tejidos o incluso a la enfermedad inflamatoria. [...]
microorganisms, such as bacteria and parasites. However, inflammation must be a highly regulated process, otherwise, it may lead to tissue damage or even to inflammatory disease. In the nervous system, inflammatory response exerts a crucial role in promoting axonal regeneration after injury, as has been consistently shown in several models of peripheral nerve injury. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2016  

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