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Artículos Encontrados 3 registros  
1.
6 p, 668.6 KB Theoretical frameworks and approaches used within the Reserve, Resilience and Protective Factors professional interest area of the Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment / Bartrés-Faz, David (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Arenaza-Urquijo, Eider (Pasqual Maragall Foundation) ; Ewers, Michael (LMU Munich. University Hospital) ; Belleville, Sylvie (Université de Montréal) ; Chételat, G. (Normandie University) ; Franzmeier, Nicolai (LMU Munich. University Hospital) ; Gonneaud, Julie (McGill University) ; de Echevarri, José María González (Pasqual Maragall Foundation) ; Okonkwo, Ozioma (University of Wisconsin-Madison) ; Schultz, Stephanie (University of Wisconsin-Madison) ; Valenzuela, Michael (University of New South Wales) ; Stern, Yaakov (Columbia University) ; Vemuri, Prashanthi (Mayo Clinic Rochester Minnesota)
Reserve, resilience, maintenance, and related concepts are intensely debated in aging and Alzheimer's disease research. Through a short survey, we gathered information about theoretical concepts and methodologies used among research groups of the Reserve, Resilience, and Protective Factors Professional Interest Area of the Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment. [...]
2020 - 10.1002/dad2.12115
Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring, Vol. 12 (november 2020)  
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2.
14 p, 1.2 MB Early increase of CSF sTREM2 in Alzheimer's disease is associated with tau related-neurodegeneration but not with amyloid-β pathology / Suárez Calvet, Marc (Ludwig-Maximilians-Universität München) ; Morenas-Rodríguez, Estrella (Institut d'Investigació Biomèdica Sant Pau) ; Kleinberger, Gernot (Ludwig-Maximilians-Universität München) ; Schlepckow, Kai (German Center for Neurodegenerative Diseases (DZNE) Munich) ; Araque Caballero, Miguel Ángel (Ludwig-Maximilians-Universität München) ; Franzmeier, Nicolai (Ludwig-Maximilians-Universität München) ; Capell, Anja (Ludwig-Maximilians-Universität München) ; Fellerer, Katrin (Ludwig-Maximilians-Universität München) ; Nuscher, Brigitte (Ludwig-Maximilians-Universität München) ; Eren, Erden (Ludwig-Maximilians-Universität München) ; Levin, Johannes (German Center for Neurodegenerative Diseases (DZNE) Munich) ; Deming, Yuetiva (Washington University School of Medicine) ; Piccio, Laura (Washington University School of Medicine) ; Karch, Celeste M. (Washington University School of Medicine) ; Cruchaga, Carlos (Washington University School of Medicine) ; Shaw, Leslie M. (University of Pennsylvania) ; Trojanowski, John Q.. (University of Pennsylvania) ; Weiner, Michael (University of California at San Francisco) ; Ewers, Michael (Ludwig-Maximilians-Universität München) ; Haass, Christian (Ludwig-Maximilians-Universität München) ; Universitat Autònoma de Barcelona
TREM2 is a transmembrane receptor that is predominantly expressed by microglia in the central nervous system. Rare variants in the TREM2 gene increase the risk for late-onset Alzheimer's disease (AD). [...]
2019 - 10.1186/s13024-018-0301-5
Molecular neurodegeneration, Vol. 14 (january 2019)  
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3.
21 p, 965.2 KB CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline / Suárez-Calvet, Marc (Ludwig-Maximilians-Universität München) ; Capell, Anja (Ludwig-Maximilians-Universität München) ; Araque Caballero, Miguel Ángel (Ludwig-Maximilians-Universität München) ; Morenas-Rodríguez, Estrella (Universitat Autònoma de Barcelona) ; Fellerer, Katrin (Ludwig-Maximilians-Universität München) ; Franzmeier, Nicolai (Ludwig-Maximilians-Universität München) ; Kleinberger, Gernot (Munich Cluster for Systems Neurology (SyNergy)) ; Eren, Erden (Dokuz Eylul University, Turkey) ; Deming, Yuetiva (Washington University School of Medicine) ; Piccio, Laura (Washington University School of Medicine) ; Karch, Celeste M. (Washington University School of Medicine) ; Cruchaga, Carlos (Washington University School of Medicine) ; Paumier, Katrina (Washington University School of Medicine) ; Bateman, Randall J. (Washington University School of Medicine) ; Fagan, Anne M. (Washington University School of Medicine) ; Morris, John C. (Washington University School of Medicine) ; Levin, Johannes (Ludwig-Maximilians-Universität München) ; Danek, Adrian (Ludwig-Maximilians-Universität München) ; Jucker, Mathias (University of Tübingen) ; Masters, Colin L. (University of Melbourne) ; Rossor, Martin N. (UCL Institute of Neurology (Regne Unit)) ; Ringman, John M. (University of Southern California) ; Shaw, Leslie M. (University of Pennsylvania) ; Trojanowski, John Q.. (University of Pennsylvania) ; Weiner, Michael (University of California at San Francisco) ; Ewers, Michael (Ludwig-Maximilians-Universität München) ; Haass, Christian (Munich Cluster for Systems Neurology (SyNergy))
Progranulin (PGRN) is predominantly expressed by microglia in the brain, and genetic and experimental evidence suggests a critical role in Alzheimer's disease (AD). We asked whether expression is changed in a disease severity-specific manner in . [...]
2018 - 10.15252/emmm.201809712
EMBO Molecular Medicine, Vol. 10 (november 2018)  
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1 Franzmeier, N.
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