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11 p, 1.7 MB Long-lasting impairment of mGluR5-activated intracellular pathways in the striatum after withdrawal of cocaine self-administration / Hoffmann, Hanne Mette (University of California San Diego. Department of Reproductive Medicine) ; Crouzin, Nadine (Oxidative Stress and Neuroprotection. IBMM. CNRS UMR-5247. University of Montpellier II) ; Moreno, Estefanía (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Raivio, Noora (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Fuentes Garcia, Silvia (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut) ; McCormick, Peter J. (University of East Anglia. School of Pharmacy) ; Ortiz de Pablo, Jordi (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Vignes, Michel (Oxidative Stress and Neuroprotection. IBMM. CNRS UMR-5247. University of Montpellier II)
Background: Cocaine addiction continues to be a major heath concern, and despite public health intervention there is a lack of efficient pharmacological treatment options. A newly identified potential target are the group I metabotropic glutamate receptors, with allosteric modulators showing particular promise. [...]
2017 - 10.1093/ijnp/pyw086
International journal of neuropsychopharmacology, Vol. 20 Núm. 1 (2017) , p. 72-82  

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