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8 p, 1.6 MB Photomodulation of G protein-coupled adenosine receptors by a novel light-switchable ligand / Bahamonde, María Isabel (Institut de Bioenginyeria de Catalunya) ; Taura, Jaume (Universitat de Barcelona. Departament Patologia i Terapèutica Experimental) ; Paoletta, Silvia (National Institutes of Health) ; Gakh, Anadrei A. (National Institutes of Health) ; Chakraborty, Saibal (National Institutes of Health) ; Hernando Campos, Jordi (Universitat Autònoma de Barcelona. Departament de Química) ; Fernández Dueñas, Víctor (Universitat de Barcelona. Departament Patologia i Terapèutica Experimental) ; Jacobson, Kenneth A. (National Institutes of Health) ; Gorostiza, Pau (Institut de Bioenginyeria de Catalunya) ; Ciruela, Francisco (Universitat de Barcelona. Departament Patologia i Terapèutica Experimental)
The adenosinergic system operates through G protein-coupled adenosine receptors, which have become promising therapeutic targets for a wide range of pathological conditions. However, the ubiquity of adenosine receptors and the eventual lack of selectivity of adenosine-based drugs have frequently diminished their therapeutic potential. [...]
2014 - 10.1021/bc5003373
Bioconjugate chemistry, Vol. 25, Issue 10 (October 2014) , p. 1847-1854  

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