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30 p, 397.4 KB The IMPROVE Guidelines (Ischaemia Models : Procedural Refinements Of in Vivo Experiments) / Percie du Sert, Nathalie (National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs), London, UK) ; Alfieri, Alessio (The Roslin Institute and R(D)SVS, University of Edinburgh, Easter Bush, Midlothian, UK) ; Allan, Stuart M. (Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK) ; Carswell, Hilary V. O. (Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), University of Strathclyde, Glasgow, UK) ; Deuchar, Graeme A. (Institute of Neuroscience and Psychology, College of Medical, Veterinary and Life Sciences, University of Glasgow/Arum Biosciences, Glasgow, UK) ; Farr, Tracy D. (School of Life Sciences, University of Nottingham Medical School, Nottingham, UK) ; Flecknell, Paul (Comparative Biology Centre, Newcastle University, UK) ; Gallagher, Lindsay (Institute of Neuroscience and Psychology, College of Medical, Veterinary and Life Sciences, University of Glasgow/Arum Biosciences, Glasgow, UK) ; Gibson, Claire L. (Department of Neuroscience, Psychology and Behaviour, University of Leicester, Leicester, UK) ; Haley, Michael J. (Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK) ; Macleod, Malcolm R. (Centre for Clinical Brain Sciences. University of Edinburgh) ; McColl, Barry W. (The Roslin Institute and R(D)SVS, University of Edinburgh, Easter Bush, Midlothian, UK) ; McCabe, Christopher (Institute of Neuroscience and Psychology, College of Medical, Veterinary and Life Sciences, University of Glasgow/Arum Biosciences, Glasgow, UK) ; Morancho, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Moon, Lawrence D. F. (King's College London. Wolfson Centre for Age-Related Diseases) ; O'Neill, Michael J. (Eli Lilly and Co., Windlesham, Surrey, UK) ; Pérez de Puig, Isabel (Institut d'Investigacions Biomèdiques de Barcelona) ; Planas, Anna Maria (Institut d'Investigacions Biomèdiques de Barcelona) ; Ragan, C. Ian (NC3Rs Board, London, UK) ; Rosell Novel, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Roy, Lisa A. (Institute of Neuroscience and Psychology, College of Medical, Veterinary and Life Sciences, University of Glasgow/Arum Biosciences, Glasgow, UK) ; Ryder, Kathryn O. (Home Office, London, UK) ; Simats Oriol, Alba (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Sena, Emily S. (Centre for Clinical Brain Sciences. University of Edinburgh) ; Sutherland, Brad A. (School of Medicine, Faculty of Health, University of Tasmania, Hobart, Australia) ; Tricklebank, Mark D. (King's College London) ; Trueman, Rebecca C. (School of Life Sciences, University of Nottingham Medical School, Nottingham, UK) ; Whitfield, Lucy (University of London. Royal Veterinary College (Hatfield, Regne Unit)) ; Wong, Raymond (Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK) ; Macrae, I Mhairi (Institute of Neuroscience and Psychology, College of Medical, Veterinary and Life Sciences, University of Glasgow/Arum Biosciences, Glasgow, UK) ; Universitat Autònoma de Barcelona
Most in vivo models of ischaemic stroke target the middle cerebral artery and a spectrum of stroke severities, from mild to substantial, can be achieved. This review describes opportunities to improve the in vivo modelling of ischaemic stroke and animal welfare. [...]
2017 - 10.1177/0271678X17709185
Journal of Cerebral Blood Flow & Metabolism, Vol. 37 (august 2017) , p. 3488-3517  

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