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1.
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7 p, 384.6 KB |
Benefit of primary percutaneous coronary interventions in the elderly with ST segment elevation myocardial infarction
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Fernández-Bergés, Daniel (Instituto Universitario de Investigación Biosanitaria de Extremadura) ;
Degano, Irene R (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Gonzalez Fernandez, Reyes (Infanta Cristina University Hospital) ;
Subirana, Isaac (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Vila, Joan (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Jiménez-Navarro, Manuel (Virgen de la Victoria University Hospital) ;
Perez-Fernandez, Silvia (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Roqué, Mercé (Hospital Clinic) ;
Bayes-Genis, Antoni (Hospital Universitari Germans Trias i Pujol) ;
Fernandez-Aviles, Francisco (University Hospital Gregorio Marañon) ;
Mayorga, Antonio (Hospital Universitario Gregorio Marañón, Madrid) ;
Bertomeu-Gonzalez, Vicente (Hospital Universitario de San Juan) ;
Sanchis, Juan (Hospital Clinico Universitario, INCLIVA, Universitat de València) ;
Rodríguez Esteban, Marcos (Hospital Universitario Nuestra Senora de la Candelaria) ;
Sanchez-Hidalgo, Antonio (Consorci Sanitari de Terrassa) ;
Sanchez-Insa, Esther (Hospital Universitario Miguel Servet) ;
Elorriaga, Ane (Hospital Universitario de Basurto, Bilbao) ;
Abu Assi, Emad (Hospital Álvaro Junqueiro de Vigo, Pontevedra) ;
Nuñez, Alberto (Hospital Universitario Fundación de Alcorcón) ;
Garcia Ruiz, Jose Manuel (Hospital Universitario Central de Asturias) ;
Morrondo Valdeolmillos, Pedro (Hospital Universitario Donostia, San Sebastián) ;
Bosch-Portell, Daniel (Hospital Universitari de Girona Doctor Josep Trueta) ;
Lekuona, Iñaki (Hospital Galdakao-Usansolo) ;
Carrillo-Lopez, Andres (Hospital Universitari Son Espases) ;
Zamora, Alberto (Hospital Comarcal de Blanes) ;
Vega-Hernandez, Berta (Hospital Universitario de Cabueñes) ;
Alameda Serrano, Javier (Hospital Clínico Universitario Lozano Blesa) ;
Rubert, Catalina (Hospital Son Llàtzer) ;
Ruiz-Valdepeñas, Luis (Hospital General Universitario de Ciudad Real) ;
Quintas, Laura (Hospital de Mendaro) ;
Rodríguez-Padial, Luis (Complejo Hospitalario de Toledo) ;
Vaquero, Jessica (Hospital Universitario Araba sede Txagorritxu) ;
Martinez Dolz, Luis (Hospital Universitario La Fe) ;
Barrabes, Jose A (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Sanchez, Pedro L (Hospital Universitario Salamanca) ;
Sionis, Alessandro (Institut d'Investigació Biomèdica Sant Pau) ;
Martí-Almor, Julio (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Elosua, Roberto (Universitat de Vic) ;
Lidon, Rosa-María (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Garcia-Dorado, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Marrugat, Jaume (CIBER Enfermedades Cardiovasculares (CIBERCV)) ;
Universitat Autònoma de Barcelona
Primary percutaneous coronary intervention (P-PCI) has demonstrated its efficacy in patients with ST segment elevation myocardial infarction (STEMI). However, patients with STEMI ≥75 years receive less P-PCI than younger patients despite their higher in-hospital morbimortality. [...]
2020 -  10.1136/openhrt-2019-001169
Open Heart, Vol. 7 (august 2020)
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2.
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6 p, 617.5 KB |
The effect of intracoronary infusion of bone marrow-derived mononuclear cells on all-cause mortality in acute myocardial infarction : rationale and design of the trial
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Mathur, Anthony (Queen Mary University of London (UK)) ;
Arnold, Roman (Hospital Clínico Universitario de Valladolid) ;
Assmus, Birgit (Johann-Wolfgang-Goethe University (Germany)) ;
Bartunek, Jozef (VZW Cardiovascular Research Center Aalst (Belgium)) ;
Belmans, Ann (KU Leuven-University of Leuven & Universiteit Hasselt (Belgium)) ;
Bönig, Halvard (Johann-Wolfgang-Goethe University (Germany)) ;
Crea, Filippo (Catholic University of the Sacred Heart (Italy)) ;
Dimmeler, Stefanie (Johann-Wolfgang-Goethe University (Germany)) ;
Dowlut, Sheik (Queen Mary University of London (UK)) ;
Fernández-Avilés, Francisco (Hospital General Universitario Gregorio Marañón) ;
Galiñanes, Manuel (Hospital Universitari Vall d'Hebron) ;
García Dorado, David (Hospital Universitari Vall d'Hebron) ;
Hartikainen, Juha (Kuopio University Hospital and University of Eastern Finland (Finland)) ;
Hill, Jonathan (King's College Hospital (UK)) ;
Hogardt-Noll, Annette (t2cure (Germany)) ;
Homsy, Christian (Celyad SA (Belgium)) ;
Janssens, Stefan (University Hospitals Leuven (Belgium)) ;
Kala, Petr (Faculty Hospital and Masaryk University (Czech Republic)) ;
Kastrup, Jens (Rigshospitalet University of Copenhagen (Denmark)) ;
Martin, John (University College London (UK)) ;
Menasche, Philippe (University Paris Descartes. Assistance Publique Hopitaux de Paris (France)) ;
Miklik, Roman (Faculty Hospital and Masaryk University (Czech Republic)) ;
Mozid, Abdul (Barts Heart Centre (UK)) ;
San Román, J. Alberto (Hospital Clínico Universitario de Valladolid) ;
Sanz-Ruiz, Ricardo (Hospital General Universitario Gregorio Marañón) ;
Tendera, Michal (Medical University of Silesia (Poland)) ;
Wojakowski, Wojtek (Medical University of Silesia (Poland)) ;
Ylä-Herttuala, Seppo (Kuopio University Hospital and University of Eastern Finland (Finland)) ;
Zeiher, Andreas (Johann-Wolfgang-Goethe University (Germany)) ;
Universitat Autònoma de Barcelona
Over the past 13 years bone marrow-derived mononuclear cells () have been widely investigated for clinical efficacy in patients following acute myocardial infarction (). These early phase trials have used various surrogate markers to judge efficacy and, although promising, the results have been inconsistent. [...]
2017 - 10.1002/ejhf.829
European Journal of Heart Failure, Vol. 19, Issue 11 (November 2017) , p. 1545-1550
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3.
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15 p, 4.8 MB |
Aortic flow patterns and wall shear stress maps by 4D-flow cardiovascular magnetic resonance in the assessment of aortic dilatation in bicuspid aortic valve disease
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Rodríguez-Palomares, José Fernando (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Dux-Santoy, Lydia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Guala, Andrea (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Kale, Raquel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Maldonado, Giuliana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Teixidó-Turà, Gisela (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Galian Gay, Laura (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Huguet, Marina (Cardiac Imaging Department, CETIR-ERESA, Clínica del Pilar-Sant Jordi, Barcelona, Spain) ;
Valente, Filipa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Gutiérrez, Laura (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
González-Alujas, Teresa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Johnson, Kevin M. (Madison, WI USA) ;
Wieben, Oliver (Madison, WI USA) ;
García-Dorado, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Evangelista, Arturo (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
In patients with bicuspid valve (BAV), ascending aorta (AAo) dilatation may be caused by altered flow patterns and wall shear stress (WSS). These differences may explain different aortic dilatation morphotypes. [...]
2018 - 10.1186/s12968-018-0451-1
Journal of Cardiovascular Magnetic Resonance, Vol. 20 (april 2018)
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4.
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11 p, 1.0 MB |
Cardiomyocyte hypertrophy induced by Endonuclease G deficiency requires reactive oxygen radicals accumulation and is inhibitable by the micropeptide humanin
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Blasco, Natividad (Cell Signaling and Apoptosis group, Universitat de Lleida - IRBLleida, Lleida, Spain) ;
Cámara, Yolanda (Research Group on Neuromuscular and Mitochondrial Diseases, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona and CIBERER, Barcelona, Spain) ;
Núñez, Estefanía (Cardiovascular Proteomics group, Spanish National Center for Cardiovascular Research (CNIC) and CIBERCV Madrid, Spain) ;
Beà, Aida (Cell Signaling and Apoptosis group, Universitat de Lleida - IRBLleida, Lleida, Spain) ;
Barés, Gisel (Cell Signaling and Apoptosis group, Universitat de Lleida - IRBLleida, Lleida, Spain) ;
Forné, Carles (Biostatistics Unit, IRBLleida, Universitat de Lleida, Lleida, Spain) ;
Ruíz-Meana, Marisol (Cardiovascular Diseases Research Group, VHIR and CIBERCV, Barcelona, Spain) ;
Girón, Cristina (Cell Signaling and Apoptosis group, Universitat de Lleida - IRBLleida, Lleida, Spain) ;
Barba, Ignasi (Cardiovascular Diseases Research Group, VHIR and CIBERCV, Barcelona, Spain) ;
García-Arumí, Elena (Research Group on Neuromuscular and Mitochondrial Diseases, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona and CIBERER, Barcelona, Spain) ;
García Dorado, David (Cardiovascular Diseases Research Group, VHIR and CIBERCV, Barcelona, Spain) ;
Vázquez, Jesús (Cardiovascular Proteomics group, Spanish National Center for Cardiovascular Research (CNIC) and CIBERCV Madrid, Spain) ;
Martí Seves, Ramon (Research Group on Neuromuscular and Mitochondrial Diseases, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona and CIBERER, Barcelona, Spain) ;
Llovera, Marta (Cell Signaling and Apoptosis group, Universitat de Lleida - IRBLleida, Lleida, Spain) ;
Sanchis, Daniel (Cell Signaling and Apoptosis group, Universitat de Lleida - IRBLleida, Lleida, Spain)
The endonuclease G gene (Endog), which codes for a mitochondrial nuclease, was identified as a determinant of cardiac hypertrophy. How ENDOG controls cardiomyocyte growth is still unknown. Thus, we aimed at finding the link between ENDOG activity and cardiomyocyte growth. [...]
2018 - 10.1016/j.redox.2018.02.021
Redox biology, Vol. 16 (march 2018) , p. 146-156
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5 p, 5.1 MB |
Life-threatening and life-saving inappropriate implantable cardioverter defibrillator shocks
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Pérez Rodon, Jordi (Universitat Autònoma de Barcelona) ;
Doiny, David (Universitat Autònoma de Barcelona) ;
Miranda, Berta (Universitat Autònoma de Barcelona) ;
Rivas Gándara, Nuria (Universitat Autònoma de Barcelona) ;
Roca Luque, Ivo (Universitat Autònoma de Barcelona) ;
Francisco Pascual, Jaume (Universitat Autònoma de Barcelona) ;
Lidón, Rosa Maria (Universitat Autònoma de Barcelona) ;
García Dorado, David (Universitat Autònoma de Barcelona) ;
Moya Mitjans, Angel (Universitat Autònoma de Barcelona)
An implantable cardioverter defibrillator (ICD) lead dislodgement into the right atrium is a dangerous situation, particularly in patients in atrial fibrillation because atrial fibrillation can be sensed as ventricular fibrillation and true ventricular fibrillation induced with an inappropriate shock. [...]
2017 - 10.1002/ccr3.893
Clinical Case Reports, Vol. 5, Issue 4 (April 2017) , p. 521-525
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6 p, 488.0 KB |
Circadian variation in acute myocardial infarct size assessed by cardiovascular magnetic resonance in reperfused STEMI patients
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Bulluck, Heerajnarain (National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore) ;
Nicholas, Jennifer (London School Hygiene and Tropical Medicine, London, UK) ;
Crimi, Gabriele (Struttura Complessa Cardiologia, Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico San Matteo, Pavia, Italy) ;
White, Steven K (The Hatter Cardiovascular Institute, Institute of Cardiovascular Science, University College London, UK) ;
Ludman, Andrew J (Royal Devon and Exeter Hospital NHS Foundation Trust, Exeter, UK) ;
Pica, Silvia (Struttura Complessa Cardiologia, Azienda Ospedaliera SS: Antonio e Biagio, Alessandria, Italy) ;
Raineri, Claudia (Struttura Complessa Cardiologia, Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico San Matteo, Pavia) ;
Cabrera-Fuentes, Hector A (Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore) ;
Yellon, Derek (The Hatter Cardiovascular Institute, Institute of Cardiovascular Science, University College London) ;
Rodriguez-Palomares, Jose (Hospital Universitari Vall d'Hebron) ;
Garcia-Dorado, David (Hospital Universitari Vall d'Hebron) ;
Hausenloy, Derek J (Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore) ;
Universitat Autònoma de Barcelona
Clinical studies using serum cardiac biomarkers to investigate a circadian variation in acute myocardial infarct (MI) size in ST-segment elevation myocardial infarction (STEMI) patients reperfused by primary percutaneous coronary intervention (PPCI) have produced mixed results. [...]
2017 - 10.1016/j.ijcard.2016.12.030
International Journal of Cardiology, Vol. 230 (march 2017) , p. 149-154
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8 p, 83.7 KB |
Plasma B-type natriuretic peptide levels are poorly related to the occurrence of ischemia or ventricular arrhythmias during symptom-limited exercise in low-risk patients
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Porta, Andreu (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Barrabés, José A. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Candell-Riera, Jaume (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Agulló, Luis (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Aguadé-Bruix, Santiago (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
de León, Gustavo (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Figueras, Jaume (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Garcia-Dorado, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
The usefulness of B-type natriuretic peptide (BNP) as a marker of ischemia is controversial. BNP levels have predicted arrhythmias in various settings, but it is unknown whether they are related to exercise-induced ischemic ventricular arrhythmias. [...]
2016 - 10.5114/aoms.2016.59258
Archives of Medical Science : AMS, Vol. 12 (april 2016) , p. 341-348
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11 p, 337.7 KB |
Targeting reperfusion injury in patients with ST-segment elevation myocardial infarction : trials and tribulations
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Hausenloy, Derek J. (National Institute of Health Research University College London Hospitals Biomedical Research Centre, London W1T 7DN, UK) ;
Botker, Hans Erik (Department of Cardiology, Aarhus University Hospital Skejby, DK-8200 Aarhus N, Denmark) ;
Engstrom, Thomas (Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark) ;
Erlinge, David (Department of Cardiology, Lund University, Lund, Sweden) ;
Heusch, Gerd (Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School, Essen, Germany) ;
Ibanez, Borja (IIS-Fundación Jiménez Díaz Hospital, Madrid, Spain) ;
Kloner, Robert A. (Division of Cardiovascular Medicine, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA) ;
Ovize, Michel (UMR 1060 (CarMeN), Université Claude Bernard, Lyon, France) ;
Yellon, Derek M. (National Institute of Health Research University College London Hospitals Biomedical Research Centre, London W1T 7DN, UK) ;
Garcia-Dorado, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
2016 - 10.1093/eurheartj/ehw145
European heart journal, Vol. 38 (april 2016) , p. 935-941
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10 p, 749.9 KB |
New protein-protein interactions of mitochondrial connexin 43 in mouse heart
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Denuc, Amanda (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Núñez, Estefanía (Centro Nacional de Investigaciones Cardiovasculares Carlos III) ;
Calvo, Enrique (Centro Nacional de Investigaciones Cardiovasculares Carlos III) ;
Loureiro, Marta (Centro Nacional de Investigaciones Cardiovasculares Carlos III) ;
Miro-Casas, Elisabet (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Guarás, Adela (Centro Nacional de Investigaciones Cardiovasculares Carlos III) ;
Vázquez, Jesús (Centro Nacional de Investigaciones Cardiovasculares Carlos III) ;
Garcia Dorado, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
Connexin 43 (Cx43), the gap junction protein involved in cell-to-cell coupling in the heart, is also present in the subsarcolemmal fraction of cardiomyocyte mitochondria. It has been described to regulate mitochondrial potassium influx and respiration and to be important for ischaemic preconditioning protection, although the molecular effectors involved are not fully characterized. [...]
2016 - 10.1111/jcmm.12792
Journal of Cellular and Molecular Medicine, Vol. 20, issue 5 (May 2016) , p. 794-803
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10 p, 365.3 KB |
Hospital and 4-year mortality predictors in patients with acute pulmonary edema with and without coronary artery disease
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Figueras Bellot, Jaume (Hospital Universitari Vall d'Hebron. Servei de Cardiologia) ;
Bañeras Rius, Jordi (Hospital Universitari Vall d'Hebron. Servei de Cardiologia) ;
Peña-Gil, Carlos (Complexo Hospitalario Universitario de Vigo. Servicio de Cardiología) ;
Barrabés Riu, José Antonio (Hospital Universitari Vall d'Hebron. Servei de Cardiologia) ;
Rodríguez Palomares, José Fernando (Hospital Universitari Vall d'Hebron. Servei de Cardiologia) ;
Garcia Dorado, David (Hospital Universitari Vall d'Hebron. Servei de Cardiologia) ;
Universitat Autònoma de Barcelona
Long-term prognosis of acute pulmonary edema () remains ill defined. We evaluated demographic, echocardiographic, and angiographic data of 806 consecutive patients with with () and without coronary artery disease (non-) admitted from 2000 to 2010. [...]
2016 - 10.1161/JAHA.115.002581
Journal of the American Heart Association, Vol. 5, issue 2 (Feb. 2016)
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