Resultats globals: 11 registres trobats en 0.02 segons.
Articles, 7 registres trobats
Documents de recerca, 4 registres trobats
Articles 7 registres trobats  
1.
6 p, 617.5 KB The effect of intracoronary infusion of bone marrow‐derived mononuclear cells on all‐cause mortality in acute myocardial infarction : rationale and design of the trial / Mathur, Anthony (Queen Mary University of London (UK)) ; Arnold, Roman (Hospital Clínico Universitario de Valladolid) ; Assmus, Birgit (Johann‐Wolfgang‐Goethe University (Germany)) ; Bartunek, Jozef (VZW Cardiovascular Research Center Aalst (Belgium)) ; Belmans, Ann (KU Leuven—University of Leuven & Universiteit Hasselt (Belgium)) ; Bönig, Halvard (Johann‐Wolfgang‐Goethe University (Germany)) ; Crea, Filippo (Catholic University of the Sacred Heart (Italy)) ; Dimmeler, Stefanie (Johann‐Wolfgang‐Goethe University (Germany)) ; Dowlut, Sheik (Queen Mary University of London (UK)) ; Fernández‐Avilés, Francisco (Hospital General Universitario Gregorio Marañón) ; Galiñanes, Manuel (Hospital Universitari Vall d'Hebron) ; García Dorado, David (Hospital Universitari Vall d'Hebron) ; Hartikainen, Juha (Kuopio University Hospital and University of Eastern Finland (Finland)) ; Hill, Jonathan (King's College Hospital (UK)) ; Hogardt‐Noll, Annette (t2cure (Germany)) ; Homsy, Christian (Celyad SA (Belgium)) ; Janssens, Stefan (University Hospitals Leuven (Belgium)) ; Kala, Petr (Faculty Hospital and Masaryk University (Czech Republic)) ; Kastrup, Jens (Rigshospitalet University of Copenhagen (Denmark)) ; Martin, John (University College London (UK)) ; Menasche, Philippe (University Paris Descartes. Assistance Publique Hopitaux de Paris (France)) ; Miklik, Roman (Faculty Hospital and Masaryk University (Czech Republic)) ; Mozid, Abdul (Barts Heart Centre (UK)) ; San Román, J. Alberto (Hospital Clínico Universitario de Valladolid) ; Sanz‐Ruiz, Ricardo (Hospital General Universitario Gregorio Marañón) ; Tendera, Michal (Medical University of Silesia (Poland)) ; Wojakowski, Wojtek (Medical University of Silesia (Poland)) ; Ylä‐Herttuala, Seppo (Kuopio University Hospital and University of Eastern Finland (Finland)) ; Zeiher, Andreas (Johann‐Wolfgang‐Goethe University (Germany)) ; Universitat Autònoma de Barcelona
Over the past 13 years bone marrow‐derived mononuclear cells () have been widely investigated for clinical efficacy in patients following acute myocardial infarction (). These early phase trials have used various surrogate markers to judge efficacy and, although promising, the results have been inconsistent. [...]
2017 - 10.1002/ejhf.829
European Journal of Heart Failure, Vol. 19, Issue 11 (November 2017) , p. 1545-1550  
2.
11 p, 1.0 MB Cardiomyocyte hypertrophy induced by Endonuclease G deficiency requires reactive oxygen radicals accumulation and is inhibitable by the micropeptide humanin / Blasco, Natividad (Cell Signaling and Apoptosis group, Universitat de Lleida - IRBLleida, Lleida, Spain) ; Cámara, Yolanda (Research Group on Neuromuscular and Mitochondrial Diseases, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona and CIBERER, Barcelona, Spain) ; Núñez, Estefanía (Cardiovascular Proteomics group, Spanish National Center for Cardiovascular Research (CNIC) and CIBERCV Madrid, Spain) ; Beà, Aida (Cell Signaling and Apoptosis group, Universitat de Lleida - IRBLleida, Lleida, Spain) ; Barés, Gisel (Cell Signaling and Apoptosis group, Universitat de Lleida - IRBLleida, Lleida, Spain) ; Forné, Carles (Biostatistics Unit, IRBLleida, Universitat de Lleida, Lleida, Spain) ; Ruíz-Meana, Marisol (Cardiovascular Diseases Research Group, VHIR and CIBERCV, Barcelona, Spain) ; Girón, Cristina (Cell Signaling and Apoptosis group, Universitat de Lleida - IRBLleida, Lleida, Spain) ; Barba, Ignasi (Cardiovascular Diseases Research Group, VHIR and CIBERCV, Barcelona, Spain) ; García-Arumí, Elena (Research Group on Neuromuscular and Mitochondrial Diseases, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona and CIBERER, Barcelona, Spain) ; García Dorado, David (Cardiovascular Diseases Research Group, VHIR and CIBERCV, Barcelona, Spain) ; Vázquez, Jesús (Cardiovascular Proteomics group, Spanish National Center for Cardiovascular Research (CNIC) and CIBERCV Madrid, Spain) ; Martí, Ramon (Research Group on Neuromuscular and Mitochondrial Diseases, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona and CIBERER, Barcelona, Spain) ; Llovera, Marta (Cell Signaling and Apoptosis group, Universitat de Lleida - IRBLleida, Lleida, Spain) ; Sanchis, Daniel (Cell Signaling and Apoptosis group, Universitat de Lleida - IRBLleida, Lleida, Spain)
The endonuclease G gene (Endog), which codes for a mitochondrial nuclease, was identified as a determinant of cardiac hypertrophy. How ENDOG controls cardiomyocyte growth is still unknown. Thus, we aimed at finding the link between ENDOG activity and cardiomyocyte growth. [...]
2018 - 10.1016/j.redox.2018.02.021
Redox Biology, Vol. 16 (march 2018) , p. 146-156  
3.
5 p, 5.1 MB Life‐threatening and life‐saving inappropriate implantable cardioverter defibrillator shocks / Pérez Rodon, Jordi (Universitat Autònoma de Barcelona) ; Doiny, David (Universitat Autònoma de Barcelona) ; Miranda, Berta (Universitat Autònoma de Barcelona) ; Rivas Gándara, Nuria (Universitat Autònoma de Barcelona) ; Roca Luque, Ivo (Universitat Autònoma de Barcelona) ; Francisco Pascual, Jaume (Universitat Autònoma de Barcelona) ; Lidón, Rosa Maria (Universitat Autònoma de Barcelona) ; García Dorado, David (Universitat Autònoma de Barcelona) ; Moya Mitjans, Angel (Universitat Autònoma de Barcelona)
An implantable cardioverter defibrillator (ICD) lead dislodgement into the right atrium is a dangerous situation, particularly in patients in atrial fibrillation because atrial fibrillation can be sensed as ventricular fibrillation and true ventricular fibrillation induced with an inappropriate shock. [...]
2017 - 10.1002/ccr3.893
Clinical Case Reports, Vol. 5, Issue 4 (April 2017) , p. 521-525  
4.
10 p, 749.9 KB New protein–protein interactions of mitochondrial connexin 43 in mouse heart / Denuc, Amanda (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Núñez, Estefanía (Centro Nacional de Investigaciones Cardiovasculares Carlos III) ; Calvo, Enrique (Centro Nacional de Investigaciones Cardiovasculares Carlos III) ; Loureiro, Marta (Centro Nacional de Investigaciones Cardiovasculares Carlos III) ; Miro‐Casas, Elisabet (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Guarás, Adela (Centro Nacional de Investigaciones Cardiovasculares Carlos III) ; Vázquez, Jesús (Centro Nacional de Investigaciones Cardiovasculares Carlos III) ; Garcia Dorado, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Connexin 43 (Cx43), the gap junction protein involved in cell‐to‐cell coupling in the heart, is also present in the subsarcolemmal fraction of cardiomyocyte mitochondria. It has been described to regulate mitochondrial potassium influx and respiration and to be important for ischaemic preconditioning protection, although the molecular effectors involved are not fully characterized. [...]
2016 - 10.1111/jcmm.12792
Journal of cellular and molecular medicine, Vol. 20, issue 5 (May 2016) , p. 794-803  
5.
10 p, 365.3 KB Hospital and 4‐year mortality predictors in patients with acute pulmonary edema with and without coronary artery disease / Figueras Bellot, Jaume (Hospital Universitari Vall d'Hebron. Servei de Cardiologia) ; Bañeras Rius, Jordi (Hospital Universitari Vall d'Hebron. Servei de Cardiologia) ; Peña‐Gil, Carlos (Complexo Hospitalario Universitario de Vigo. Servicio de Cardiología) ; Barrabés Riu, José Antonio (Hospital Universitari Vall d'Hebron. Servei de Cardiologia) ; Rodríguez Palomares, José Fernando (Hospital Universitari Vall d'Hebron. Servei de Cardiologia) ; Garcia Dorado, David (Hospital Universitari Vall d'Hebron. Servei de Cardiologia) ; Universitat Autònoma de Barcelona
Long‐term prognosis of acute pulmonary edema () remains ill defined. We evaluated demographic, echocardiographic, and angiographic data of 806 consecutive patients with with () and without coronary artery disease (non‐) admitted from 2000 to 2010. [...]
2016 - 10.1161/JAHA.115.002581
Journal of the American Heart Association, Vol. 5, issue 2 (Feb. 2016)  
6.
13 p, 340.4 KB ESC working group cellular biology of the heart : position paper: improving the preclinical assessment of novel cardioprotective therapies / Lecour, Sandrine (Hatter Institute for Cardiovascular Research (Àfrica)) ; Bøtker, Hans E. (Aarhus Universitetshospital) ; Condorelli, Gianluigi (Instituto Clinico Humanitas (Milano, Itàlia)) ; Davidson, Sean M. (Hatter Institute for Cardiovascular Research (Londres, Regne Unit)) ; García Dorado, David (Universitat Autònoma de Barcelona) ; Engel, Felix B. (Friedrich-Alexander-Universität Erlangen-Nürnberg) ; Ferdinandy, Peter (Semmelweis Egyetem. Department of Pharmacology and Pharmacotherapy) ; Heusch, Gerd (Universitätsklinikum Essen) ; Madonna, Rosalinda (Università degli Studi "G. d'Annunzio" Chieti) ; Ovize, Michel (Université Claude Bernard Lyon 1) ; Ruiz-Meana, Marisol (Vall d'Hebron Institut de Recerca. Departament de Cardiologia) ; Schulz, Rainer (Justus Liebig-Universität Gießen) ; Sluijter, Joost P.G. (Universitair Medisch Centrum Utrecht) ; Van Laake, Linda W. (Universitair Medisch Centrum Utrecht) ; Yellon, Derek M. (Hatter Institute for Cardiovascular Research (Londres, Regne Unit)) ; Hausenloy, Derek J. (Hatter Institute for Cardiovascular Research (Londres, Regne Unit))
Ischaemic heart disease (IHD) remains the leading cause of death and disability worldwide. As a result, novel therapies are still needed to protect the heart from the detrimental effects of acute ischaemia–reperfusion injury, in order to improve clinical outcomes in IHD patients. [...]
2014 - 10.1093/cvr/cvu225
Cardiovascular research, Vol. 104, issue 3 (Dec. 2014) , p. 399–411  
7.
12 p, 565.3 KB Impact of Triple Therapy in Elderly Patients with Atrial Fibrillation Undergoing Percutaneous Coronary Intervention / Sambola, Antonia (Hospital Universitari Vall d'Hebron) ; Mutuberría Urdániz, María (Hospital Universitari Vall d'Hebron) ; García Del Blanco, Bruno (Hospital Universitari Vall d'Hebron) ; Alonso, Albert (Hospital Universitari Vall d'Hebron) ; Barrabés Riu, José Antonio (Hospital Universitari Vall d'Hebron) ; Bueno, Héctor (Hospital General Universitario Gregorio Marañón) ; Alfonso, Fernando (Hospital Clínico San Carlos (Madrid)) ; Cequier, Ángel (Hospital Universitari de Bellvitge) ; Zueco, Javier (Hospital Universitario Marqués de Valdecilla (Santander)) ; Rodríguez Leor, Oriol (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Tornos Mas, Pilar (Hospital Universitari Vall d'Hebron) ; García Dorado, David (Hospital Universitari Vall d'Hebron)
Background and purpose: Selecting an ideal antithrombotic therapy for elderly patients with atrial fibrillation (AF) undergoing percutaneous coronary intervention (PCI) can be challenging since they have a higher thromboembolic and bleeding risk than younger patients. [...]
2016 - 10.1371/journal.pone.0147245
PloS one, Vol. 11 Núm. 1 (January 2016)  

Documents de recerca 4 registres trobats  
1.
186 p, 5.7 MB Eficàcia i seguretat de la simvastatina administrada en la fase aguda de la isquèmia cerebral experimental / Campos Martorell, Mireia ; Hernández Guillamon, Mar, dir. ; Montaner, Joan, dir. ; García-Dorado, David ; Universitat Autònoma de Barcelona. Departament de Medicina
Malgrat tots els esforços realitzats, la realitat és que l'ictus continua sent una de les principals causes de mortalitat i d'incapacitat arreu del món. Actualment, l'únic tractament aprovat per la FDA en la fase aguda de l'ictus isquèmic és el trombolític rt-PA, que tot i haver quedat àmpliament demostrada la seva eficàcia, també se li atribueixen una sèrie d'inconvenients tals com la impossibilitat d'administrar-lo més enllà de les 4. [...]
Despite all the past clinical efforts , stroke remains a major cause of death and disability worldwide. Currently, the only treatment approved by the FDA during the acute phase of ischemic stroke is the thrombolytic rt-PA, which despite its great effectiveness has been widely demostrated, it has also a number of drawbacks such as the impossibility of administrating it beyond 4. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2015  
2.
142 p, 3.8 MB Analysis of the haemodynamic and biomechanical properties of the lumina in aortic dissections using an integrated approach focussing on the complementary value of in-silico, in-vitro and invivo assessments / Rudenick, Paula Andrea ; Evangelista Masip, Arturo, dir. ; Bijnens, Bart Hendrik, dir. ; García Dorado, David ; Universitat Autònoma de Barcelona. Departament de Medicina
El seguimiento y el manejo de disecciones aórticas de tipo B siguen siendo un gran reto en la práctica clínica. En la fase aguda, la disección aórtica de tipo B es en general menos letal que la disección de tipo A y es tratada médicamente. [...]
The follow-up and management of chronic type B aortic dissections continue being highly challenging in clinical practice. In the acute phase, an acute type B aortic dissection is in general less lethal than a type A dissection and medically treated. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2014  
3.
190 p, 5.6 MB Desarrollo de un modelo murino in vivo de isquemia y reperfusión miocárdica. caracterización de la muerte celular y efecto de la obesidad en la inflamación y el remodelado ventricular / Poncelas Nozal, Marcos ; García Dorado, David, dir. ; Inserte, Javier, dir. ; Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia
La muerte de células miocárdicas secundaria a una oclusión coronaria aguda es la responsable directa de la mayoría de las complicaciones que padecen los pacientes que ingresan en el hospital con un síndrome coronario agudo (SCA). [...]
Myocardial cell death secondary to acute coronary occlusion is directly responsible for most of the complications reported in patients with an acute coronary syndrome. After an acute coronary infarction, the rapid restoration of coronary flow or reperfusion is the most effective strategy to limit the death of ischemic cardiomyocytes. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2014  
4.
207 p, 5.4 MB Identificación y uso de biomarcadores pronósticos en el ictus isquémico / García Berrocoso, Teresa ; Montaner, Joan, dir. ; Fernández Cadenas, Israel, dir. ; Delgado Martínez, Pilar, dir. ; García Dorado, David ; Universitat Autònoma de Barcelona. Departament d'Antropologia Social i Cultural
El ictus es una enfermedad con una elevada morbimortalidad, suponiendo la segunda causa de muerte a nivel mundial y una de las principales causas de discapacidad en el adulto. Aun así, la heterogeneidad entre los pacientes con ictus dificulta anticipar el pronóstico de la enfermedad. [...]
Stroke is a severe disease, being the second cause of death worldwide and one of the main causes of disability. Heterogeneity among stroke patients makes difficult to anticipate the prognosis of the disease. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2014  

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