Resultats globals: 17 registres trobats en 0.02 segons.
Articles, 13 registres trobats
Documents de recerca, 4 registres trobats
Articles 13 registres trobats  1 - 10següent  anar al registre:
1.
6 p, 617.5 KB The effect of intracoronary infusion of bone marrow-derived mononuclear cells on all-cause mortality in acute myocardial infarction : rationale and design of the trial / Mathur, Anthony (Queen Mary University of London (UK)) ; Arnold, Roman (Hospital Clínico Universitario de Valladolid) ; Assmus, Birgit (Johann-Wolfgang-Goethe University (Germany)) ; Bartunek, Jozef (VZW Cardiovascular Research Center Aalst (Belgium)) ; Belmans, Ann (KU Leuven-University of Leuven & Universiteit Hasselt (Belgium)) ; Bönig, Halvard (Johann-Wolfgang-Goethe University (Germany)) ; Crea, Filippo (Catholic University of the Sacred Heart (Italy)) ; Dimmeler, Stefanie (Johann-Wolfgang-Goethe University (Germany)) ; Dowlut, Sheik (Queen Mary University of London (UK)) ; Fernández-Avilés, Francisco (Hospital General Universitario Gregorio Marañón) ; Galiñanes, Manuel (Hospital Universitari Vall d'Hebron) ; García Dorado, David (Hospital Universitari Vall d'Hebron) ; Hartikainen, Juha (Kuopio University Hospital and University of Eastern Finland (Finland)) ; Hill, Jonathan (King's College Hospital (UK)) ; Hogardt-Noll, Annette (t2cure (Germany)) ; Homsy, Christian (Celyad SA (Belgium)) ; Janssens, Stefan (University Hospitals Leuven (Belgium)) ; Kala, Petr (Faculty Hospital and Masaryk University (Czech Republic)) ; Kastrup, Jens (Rigshospitalet University of Copenhagen (Denmark)) ; Martin, John (University College London (UK)) ; Menasche, Philippe (University Paris Descartes. Assistance Publique Hopitaux de Paris (France)) ; Miklik, Roman (Faculty Hospital and Masaryk University (Czech Republic)) ; Mozid, Abdul (Barts Heart Centre (UK)) ; San Román, J. Alberto (Hospital Clínico Universitario de Valladolid) ; Sanz-Ruiz, Ricardo (Hospital General Universitario Gregorio Marañón) ; Tendera, Michal (Medical University of Silesia (Poland)) ; Wojakowski, Wojtek (Medical University of Silesia (Poland)) ; Ylä-Herttuala, Seppo (Kuopio University Hospital and University of Eastern Finland (Finland)) ; Zeiher, Andreas (Johann-Wolfgang-Goethe University (Germany)) ; Universitat Autònoma de Barcelona
Over the past 13 years bone marrow-derived mononuclear cells () have been widely investigated for clinical efficacy in patients following acute myocardial infarction (). These early phase trials have used various surrogate markers to judge efficacy and, although promising, the results have been inconsistent. [...]
2017 - 10.1002/ejhf.829
European Journal of Heart Failure, Vol. 19, Issue 11 (November 2017) , p. 1545-1550  
2.
15 p, 4.8 MB Aortic flow patterns and wall shear stress maps by 4D-flow cardiovascular magnetic resonance in the assessment of aortic dilatation in bicuspid aortic valve disease / Rodríguez-Palomares, José Fernando (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Dux-Santoy, Lydia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Guala, Andrea (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Kale, Raquel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Maldonado, Giuliana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Teixidó-Turà, Gisela (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Galian, Laura (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Huguet, Marina (Cardiac Imaging Department, CETIR-ERESA, Clínica del Pilar-Sant Jordi, Barcelona, Spain) ; Valente, Filipa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Gutiérrez, Laura (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; González-Alujas, Teresa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Johnson, Kevin M. (Madison, WI USA) ; Wieben, Oliver (Madison, WI USA) ; García-Dorado, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Evangelista, Arturo (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
In patients with bicuspid valve (BAV), ascending aorta (AAo) dilatation may be caused by altered flow patterns and wall shear stress (WSS). These differences may explain different aortic dilatation morphotypes. [...]
2018 - 10.1186/s12968-018-0451-1
Journal of Cardiovascular Magnetic Resonance, Vol. 20 (april 2018)  
3.
11 p, 1.0 MB Cardiomyocyte hypertrophy induced by Endonuclease G deficiency requires reactive oxygen radicals accumulation and is inhibitable by the micropeptide humanin / Blasco, Natividad (Cell Signaling and Apoptosis group, Universitat de Lleida - IRBLleida, Lleida, Spain) ; Cámara, Yolanda (Research Group on Neuromuscular and Mitochondrial Diseases, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona and CIBERER, Barcelona, Spain) ; Núñez, Estefanía (Cardiovascular Proteomics group, Spanish National Center for Cardiovascular Research (CNIC) and CIBERCV Madrid, Spain) ; Beà, Aida (Cell Signaling and Apoptosis group, Universitat de Lleida - IRBLleida, Lleida, Spain) ; Barés, Gisel (Cell Signaling and Apoptosis group, Universitat de Lleida - IRBLleida, Lleida, Spain) ; Forné, Carles (Biostatistics Unit, IRBLleida, Universitat de Lleida, Lleida, Spain) ; Ruíz-Meana, Marisol (Cardiovascular Diseases Research Group, VHIR and CIBERCV, Barcelona, Spain) ; Girón, Cristina (Cell Signaling and Apoptosis group, Universitat de Lleida - IRBLleida, Lleida, Spain) ; Barba, Ignasi (Cardiovascular Diseases Research Group, VHIR and CIBERCV, Barcelona, Spain) ; García-Arumí, Elena (Research Group on Neuromuscular and Mitochondrial Diseases, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona and CIBERER, Barcelona, Spain) ; García Dorado, David (Cardiovascular Diseases Research Group, VHIR and CIBERCV, Barcelona, Spain) ; Vázquez, Jesús (Cardiovascular Proteomics group, Spanish National Center for Cardiovascular Research (CNIC) and CIBERCV Madrid, Spain) ; Martí Seves, Ramon (Research Group on Neuromuscular and Mitochondrial Diseases, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona and CIBERER, Barcelona, Spain) ; Llovera, Marta (Cell Signaling and Apoptosis group, Universitat de Lleida - IRBLleida, Lleida, Spain) ; Sanchis, Daniel (Cell Signaling and Apoptosis group, Universitat de Lleida - IRBLleida, Lleida, Spain)
The endonuclease G gene (Endog), which codes for a mitochondrial nuclease, was identified as a determinant of cardiac hypertrophy. How ENDOG controls cardiomyocyte growth is still unknown. Thus, we aimed at finding the link between ENDOG activity and cardiomyocyte growth. [...]
2018 - 10.1016/j.redox.2018.02.021
Redox biology, Vol. 16 (march 2018) , p. 146-156  
4.
5 p, 5.1 MB Life-threatening and life-saving inappropriate implantable cardioverter defibrillator shocks / Pérez Rodon, Jordi (Universitat Autònoma de Barcelona) ; Doiny, David (Universitat Autònoma de Barcelona) ; Miranda, Berta (Universitat Autònoma de Barcelona) ; Rivas Gándara, Nuria (Universitat Autònoma de Barcelona) ; Roca Luque, Ivo (Universitat Autònoma de Barcelona) ; Francisco Pascual, Jaume (Universitat Autònoma de Barcelona) ; Lidón, Rosa Maria (Universitat Autònoma de Barcelona) ; García Dorado, David (Universitat Autònoma de Barcelona) ; Moya Mitjans, Angel (Universitat Autònoma de Barcelona)
An implantable cardioverter defibrillator (ICD) lead dislodgement into the right atrium is a dangerous situation, particularly in patients in atrial fibrillation because atrial fibrillation can be sensed as ventricular fibrillation and true ventricular fibrillation induced with an inappropriate shock. [...]
2017 - 10.1002/ccr3.893
Clinical Case Reports, Vol. 5, Issue 4 (April 2017) , p. 521-525  
5.
6 p, 488.0 KB Circadian variation in acute myocardial infarct size assessed by cardiovascular magnetic resonance in reperfused STEMI patients / Bulluck, Heerajnarain (National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore) ; Nicholas, Jennifer (London School Hygiene and Tropical Medicine, London, UK) ; Crimi, Gabriele (Struttura Complessa Cardiologia, Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico San Matteo, Pavia, Italy) ; White, Steven K (The Hatter Cardiovascular Institute, Institute of Cardiovascular Science, University College London, UK) ; Ludman, Andrew J (Royal Devon and Exeter Hospital NHS Foundation Trust, Exeter, UK) ; Pica, Silvia (Struttura Complessa Cardiologia, Azienda Ospedaliera SS: Antonio e Biagio, Alessandria, Italy) ; Raineri, Claudia (Struttura Complessa Cardiologia, Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico San Matteo, Pavia) ; Cabrera-Fuentes, Hector A (Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore) ; Yellon, Derek (The Hatter Cardiovascular Institute, Institute of Cardiovascular Science, University College London) ; Rodriguez-Palomares, Jose (Hospital Universitari Vall d'Hebron) ; Garcia-Dorado, David (Hospital Universitari Vall d'Hebron) ; Hausenloy, Derek J (Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore) ; Universitat Autònoma de Barcelona
Clinical studies using serum cardiac biomarkers to investigate a circadian variation in acute myocardial infarct (MI) size in ST-segment elevation myocardial infarction (STEMI) patients reperfused by primary percutaneous coronary intervention (PPCI) have produced mixed results. [...]
2017 - 10.1016/j.ijcard.2016.12.030
International Journal of Cardiology, Vol. 230 (march 2017) , p. 149-154  
6.
10 p, 749.9 KB New protein-protein interactions of mitochondrial connexin 43 in mouse heart / Denuc, Amanda (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Núñez, Estefanía (Centro Nacional de Investigaciones Cardiovasculares Carlos III) ; Calvo, Enrique (Centro Nacional de Investigaciones Cardiovasculares Carlos III) ; Loureiro, Marta (Centro Nacional de Investigaciones Cardiovasculares Carlos III) ; Miro-Casas, Elisabet (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Guarás, Adela (Centro Nacional de Investigaciones Cardiovasculares Carlos III) ; Vázquez, Jesús (Centro Nacional de Investigaciones Cardiovasculares Carlos III) ; Garcia Dorado, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Connexin 43 (Cx43), the gap junction protein involved in cell-to-cell coupling in the heart, is also present in the subsarcolemmal fraction of cardiomyocyte mitochondria. It has been described to regulate mitochondrial potassium influx and respiration and to be important for ischaemic preconditioning protection, although the molecular effectors involved are not fully characterized. [...]
2016 - 10.1111/jcmm.12792
Journal of Cellular and Molecular Medicine, Vol. 20, issue 5 (May 2016) , p. 794-803  
7.
10 p, 365.3 KB Hospital and 4-year mortality predictors in patients with acute pulmonary edema with and without coronary artery disease / Figueras Bellot, Jaume (Hospital Universitari Vall d'Hebron. Servei de Cardiologia) ; Bañeras Rius, Jordi (Hospital Universitari Vall d'Hebron. Servei de Cardiologia) ; Peña-Gil, Carlos (Complexo Hospitalario Universitario de Vigo. Servicio de Cardiología) ; Barrabés Riu, José Antonio (Hospital Universitari Vall d'Hebron. Servei de Cardiologia) ; Rodríguez Palomares, José Fernando (Hospital Universitari Vall d'Hebron. Servei de Cardiologia) ; Garcia Dorado, David (Hospital Universitari Vall d'Hebron. Servei de Cardiologia) ; Universitat Autònoma de Barcelona
Long-term prognosis of acute pulmonary edema () remains ill defined. We evaluated demographic, echocardiographic, and angiographic data of 806 consecutive patients with with () and without coronary artery disease (non-) admitted from 2000 to 2010. [...]
2016 - 10.1161/JAHA.115.002581
Journal of the American Heart Association, Vol. 5, issue 2 (Feb. 2016)  
8.
10 p, 1.1 MB Clinical benefit of adenosine as an adjunct to reperfusion in ST-elevation myocardial infarction patients : An updated meta-analysis of randomized controlled trials / Bulluck, Heerajnarain (The Heart Hospital) ; Sirker, Alex (The Heart Hospital) ; Loke, Yoon K. (University of East Anglia) ; Garcia-Dorado, David (Hospital Vall d'Hebron. Departament de Cardiologia) ; Hausenloy, Derek J. (National Heart Research Institute Singapore) ; Universitat Autònoma de Barcelona
Adenosine administered as an adjunct to reperfusion can reduce coronary no-reflow and limit myocardial infarct (MI) size in ST-segment elevation myocardial infarction (STEMI) patients. Whether adjunctive adenosine therapy can improve clinical outcomes in reperfused STEMI patients is not clear and is investigated in this meta-analysis of 13 randomized controlled trials (RCTs). [...]
2016 - 10.1016/j.ijcard.2015.09.005
International Journal of Cardiology, Vol. 202 (january 2016) , p. 228-237  
9.
10 p, 447.5 KB Genetic association study of coronary collateral circulation in patients with coronary artery disease using 22 single nucleotide polymorphisms corresponding to 10 genes involved in postischemic neovascularization / Duran, Joan (Universitat de Barcelona. Departament de Patologia i Terapèutica Experimental) ; Olavarría, Pilar Sánchez (Departamento de Estadística, Facultad de Ciencias, Universidad de Valparaíso) ; Mola, Marina (Neurovascular Research Group (NEUVAS), Parc de Recerca Biomèdica de Barcelona) ; Götzens, Víctor (Universitat de Barcelona. Departament de Patologia i Terapèutica Experimental) ; Carballo, Julio (Centre Cardiovascular Sant Jordi) ; Pelegrina, Eva Martín (Centre Cardiovascular Sant Jordi) ; Petit, Màrius (Centre Cardiovascular Sant Jordi) ; Abdul-Jawad Altisent, Omar (Department of Cardiology. Hospital Mútua de Terrassa) ; Otaegui, Imanol (Hospital Universitari Vall d'Hebron,) ; del Blanco, Bruno García (Hospital Universitari Vall d'Hebron) ; García-Dorado, David (Hospital Universitari Vall d'Hebron) ; Reig, Josep (Universitat Autònoma de Barcelona. Departament de Ciències Morfològiques) ; Cordero, Alex (Àrea Epigenetics and Cancer Biology Area, Institut d'Investigació Biomèdica de Bellvitge (IDIBELL)) ; de Anta, Josep Maria (Departament de Patologia i Terapèutica Experimental. Universitat de Barcelona)
Collateral growth in patients with coronary artery disease (CAD) is highly heterogeneous. Although multiple factors are thought to play a role in collateral development, the contribution of genetic factors to coronary collateral circulation (CCC) is largely unknown. [...]
2015 - 10.1186/s12872-015-0027-z
BMC Cardiovascular disorders, Vol. 15 (may 2015)  
10.
13 p, 340.4 KB ESC working group cellular biology of the heart : position paper: improving the preclinical assessment of novel cardioprotective therapies / Lecour, Sandrine (Hatter Institute for Cardiovascular Research (Àfrica)) ; Bøtker, Hans E. (Aarhus Universitetshospital) ; Condorelli, Gianluigi (Instituto Clinico Humanitas (Milano, Itàlia)) ; Davidson, Sean M. (Hatter Institute for Cardiovascular Research (Londres, Regne Unit)) ; García Dorado, David (Universitat Autònoma de Barcelona) ; Engel, Felix B. (Friedrich-Alexander-Universität Erlangen-Nürnberg) ; Ferdinandy, Peter (Semmelweis Egyetem. Department of Pharmacology and Pharmacotherapy) ; Heusch, Gerd (Universitätsklinikum Essen) ; Madonna, Rosalinda (Università degli Studi "G. d'Annunzio" Chieti) ; Ovize, Michel (Université Claude Bernard Lyon 1) ; Ruiz-Meana, Marisol (Vall d'Hebron Institut de Recerca. Departament de Cardiologia) ; Schulz, Rainer (Justus Liebig-Universität Gießen) ; Sluijter, Joost P.G. (Universitair Medisch Centrum Utrecht) ; Van Laake, Linda W. (Universitair Medisch Centrum Utrecht) ; Yellon, Derek M. (Hatter Institute for Cardiovascular Research (Londres, Regne Unit)) ; Hausenloy, Derek J. (Hatter Institute for Cardiovascular Research (Londres, Regne Unit))
Ischaemic heart disease (IHD) remains the leading cause of death and disability worldwide. As a result, novel therapies are still needed to protect the heart from the detrimental effects of acute ischaemia-reperfusion injury, in order to improve clinical outcomes in IHD patients. [...]
2014 - 10.1093/cvr/cvu225
Cardiovascular research, Vol. 104, issue 3 (Dec. 2014) , p. 399-411  

Articles : 13 registres trobats   1 - 10següent  anar al registre:
Documents de recerca 4 registres trobats  
1.
186 p, 5.7 MB Eficàcia i seguretat de la simvastatina administrada en la fase aguda de la isquèmia cerebral experimental / Campos Martorell, Mireia ; Hernández Guillamon, Mar, dir. ; Montaner, Joan, dir. ; García-Dorado, David ; Universitat Autònoma de Barcelona. Departament de Medicina
Malgrat tots els esforços realitzats, la realitat és que l'ictus continua sent una de les principals causes de mortalitat i d'incapacitat arreu del món. Actualment, l'únic tractament aprovat per la FDA en la fase aguda de l'ictus isquèmic és el trombolític rt-PA, que tot i haver quedat àmpliament demostrada la seva eficàcia, també se li atribueixen una sèrie d'inconvenients tals com la impossibilitat d'administrar-lo més enllà de les 4. [...]
Despite all the past clinical efforts , stroke remains a major cause of death and disability worldwide. Currently, the only treatment approved by the FDA during the acute phase of ischemic stroke is the thrombolytic rt-PA, which despite its great effectiveness has been widely demostrated, it has also a number of drawbacks such as the impossibility of administrating it beyond 4. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2015  
2.
142 p, 3.8 MB Analysis of the haemodynamic and biomechanical properties of the lumina in aortic dissections using an integrated approach focussing on the complementary value of in-silico, in-vitro and invivo assessments / Rudenick, Paula Andrea ; Evangelista Masip, Arturo, dir. ; Bijnens, Bart Hendrik, dir. ; García Dorado, David ; Universitat Autònoma de Barcelona. Departament de Medicina
El seguimiento y el manejo de disecciones aórticas de tipo B siguen siendo un gran reto en la práctica clínica. En la fase aguda, la disección aórtica de tipo B es en general menos letal que la disección de tipo A y es tratada médicamente. [...]
The follow-up and management of chronic type B aortic dissections continue being highly challenging in clinical practice. In the acute phase, an acute type B aortic dissection is in general less lethal than a type A dissection and medically treated. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2014  
3.
190 p, 5.6 MB Desarrollo de un modelo murino in vivo de isquemia y reperfusión miocárdica. caracterización de la muerte celular y efecto de la obesidad en la inflamación y el remodelado ventricular / Poncelas Nozal, Marcos ; García Dorado, David, dir. ; Inserte, Javier, dir. ; Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia
La muerte de células miocárdicas secundaria a una oclusión coronaria aguda es la responsable directa de la mayoría de las complicaciones que padecen los pacientes que ingresan en el hospital con un síndrome coronario agudo (SCA). [...]
Myocardial cell death secondary to acute coronary occlusion is directly responsible for most of the complications reported in patients with an acute coronary syndrome. After an acute coronary infarction, the rapid restoration of coronary flow or reperfusion is the most effective strategy to limit the death of ischemic cardiomyocytes. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2014  
4.
207 p, 5.4 MB Identificación y uso de biomarcadores pronósticos en el ictus isquémico / García Berrocoso, Teresa ; Montaner, Joan, dir. ; Fernández Cadenas, Israel, dir. ; Delgado Martínez, Pilar, dir. ; García Dorado, David ; Universitat Autònoma de Barcelona. Departament d'Antropologia Social i Cultural
El ictus es una enfermedad con una elevada morbimortalidad, suponiendo la segunda causa de muerte a nivel mundial y una de las principales causas de discapacidad en el adulto. Aun así, la heterogeneidad entre los pacientes con ictus dificulta anticipar el pronóstico de la enfermedad. [...]
Stroke is a severe disease, being the second cause of death worldwide and one of the main causes of disability. Heterogeneity among stroke patients makes difficult to anticipate the prognosis of the disease. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2014  

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