Resultats globals: 5 registres trobats en 0.02 segons.
Articles, 5 registres trobats
Articles 5 registres trobats  
1.
47 p, 816.8 KB Highly versatile polyelectrolyte complexes for improving the enzyme replacement therapy of lysosomal storage disorders. / Giannotti, MI (Universitat de Barcelona. Departament de Química física) ; Abasolo, Ibane (Universitat Autònoma de Barcelona. Vall d'Hebron Institut de Recerca) ; Oliva, Mireia (Universitat de Barcelona. Departament de Farmàcia i Tecnologia Farmacèutica, i Fisicoquímica) ; Andrade, Fernanda (Universitat de Barcelona. Departament de Farmàcia i Tecnologia Farmacèutica, i Fisicoquímica) ; García-Aranda, Natalia (Universitat Autònoma de Barcelona. Vall d'Hebron Institut de Recerca) ; Melgarejo, Marta (Combinatorial Chemistry Unit, Barcelona Science Park (Baldiri Reixac)) ; Pulido, Daniel (Combinatorial Chemistry Unit, Barcelona Science Park (Baldiri Reixac)) ; Corchero Nieto, José Luis (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Fernández, Yolanda (Universitat Autònoma de Barcelona. Vall d'Hebron Institut de Recerca) ; Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Royo, Miriam (Combinatorial Chemistry Unit, Barcelona Science Park (Baldiri Reixac)) ; Garcia-Parajo, Maria F. (Institut de Ciencies Fotoniques, The Barcelona Institute of Science and Technology) ; Sanz, Fausto (Combinatorial Chemistry Unit, Barcelona Science Park (Baldiri Reixac)) ; Simó Schwartz Jr (Universitat Autònoma de Barcelona. Vall d'Hebron Institut de Recerca)
Lysosomal storage disorders are currently treated by enzyme replacement therapy (ERT) through the direct administration of the unprotected recombinant protein to the patients. Herein we present an ionically crosslinked polyelectrolyte complex (PEC) composed of trimethyl chitosan (TMC) and -galactosidase A (GLA), the defective enzyme in Fabry disease, with the capability of directly targeting endothelial cells by incorporating peptide ligands containing the RGD sequence. [...]
2016 - 10.1021/acsami.6b08356
ACS applied materials & interfaces, Vol. 8 Núm 39 (Octubre 2016) , p. 25741-25752  
2.
4 p, 214.8 KB Single-molecule photobleaching probes the exciton wave function in a multichromophoric system / Hernando Campos, Jordi (Institute for Nanotechnology (Enschede, Països Baixos)) ; Hoogenboom, Jacob P. (Institute for Nanotechnology (Enschede, Països Baixos)) ; van Dijk, Erik M. H. P. (Institute for Nanotechnology (Enschede, Països Baixos)) ; García López, Juan José (Institute for Nanotechnology (Enschede, Països Baixos)) ; Crego Calama, Mercedes (Institute for Nanotechnology (Enschede, Països Baixos)) ; Reinhoudt, David N. (Institute for Nanotechnology (Enschede, Països Baixos)) ; van Hulst, Niek F. (Institute for Nanotechnology (Enschede, Països Baixos)) ; García Parajó, María F. (Institute for Nanotechnology (Enschede, Països Baixos)) ; American Physical Society
The exciton wave function of a trichromophoric system is investigated by means of single molecule spectroscopy at room temperature. Individual trimers exhibit superradiance and loss of vibronic structure in emission spectrum, features proving exciton delocalization. [...]
2004 - 10.1103/PhysRevLett.93.236404
Physical review letters, Vol. 93, Issue 23 (December 2004) , p. 236404  
3.
4 p, 134.6 KB Single-molecule pump-probe detection resolves ultrafast pathways in individual and coupled quantum systems / van Dijk, Erik M. H. P. (Institute for Nanotechnology (Enschede, Països Baixos)) ; Hernando Campos, Jordi (Institute for Nanotechnology (Enschede, Països Baixos)) ; García López, Juan José (Institute for Nanotechnology (Enschede, Països Baixos)) ; Crego Calama, Mercedes (Institute for Nanotechnology (Enschede, Països Baixos)) ; Reinhoudt, David N. (Institute for Nanotechnology (Enschede, Països Baixos)) ; Kuipers, Laurens (Institute for Nanotechnology (Enschede, Països Baixos)) ; García Parajó, María F. (Institute for Nanotechnology (Enschede, Països Baixos)) ; van Hulst, Niek F. (Institute for Nanotechnology (Enschede, Països Baixos)) ; American Physical Society
We report the first experimental study of individual molecules with femtosecond time resolution using a novel ultrafast single-molecule pump-probe method. A wide range of relaxation times from below 100 up to 400 fs is found, revealing energy redistribution over different vibrational modes and phonon coupling to the nanoenvironment. [...]
2005 - 10.1103/PhysRevLett.94.078302
Physical review letters, Vol. 94, Issue 7 (February 2005) , p. 78302  
4.
4 p, 253.5 KB Power-law-distributed dark states are the main pathway for photobleaching of single organic molecules / Hoogenboom, Jacob P. (Institute for Nanotechnology (Enschede, Països Baixos)) ; van Dijk, Erik M. H. P. (Institute for Nanotechnology (Enschede, Països Baixos)) ; Hernando Campos, Jordi (Institute for Nanotechnology (Enschede, Països Baixos)) ; van Hulst, Niek F. (Institute for Nanotechnology (Enschede, Països Baixos)) ; García Parajó, María F. (Institute for Nanotechnology (Enschede, Països Baixos)) ; American Physical Society
We exploit the strong excitonic coupling in a superradiant trimer molecule to distinguish between long-lived collective dark states and photobleaching events. The population and depopulation kinetics of the dark states in a single molecule follow power-law statistics over 5 orders of magnitude in time. [...]
2005 - 10.1103/PhysRevLett.95.097401
Physical review letters, Vol. 95, Issue 9 (August 2005) , p. 097401  
5.
4 p, 224.2 KB Effect of disorder on ultrafast exciton dynamics probed by single molecule spectroscopy / Hernando Campos, Jordi (Universitat Autònoma de Barcelona. Departament de Química) ; van Dijk, Erik M. H. P. (Institute for Nanotechnology (Enschede, Països Baixos)) ; Hoogenboom, Jacob P. (Institute for Nanotechnology (Enschede, Països Baixos)) ; García López, Juan José (Institute for Nanotechnology (Enschede, Països Baixos)) ; Reinhoudt, David N. (Institute for Nanotechnology (Enschede, Països Baixos)) ; Crego Calama, Mercedes (Institute for Nanotechnology (Enschede, Països Baixos)) ; García Parajó, María F. (Institució Catalana de Recerca i Estudis Avançats) ; van Hulst, Niek F. (Institut de Ciències Fotòniques (Castelldefels, Catalunya)) ; American Physical Society
We present a single-molecule study unraveling the effect of static disorder on the vibrational-assisted ultrafast exciton dynamics in multichromophoric systems. For every single complex, we probe the initial exciton relaxation process by an ultrafast pump-probe approach and the coupling to vibrational modes by emission spectra, while fluorescence lifetime analysis measures the amount of static disorder. [...]
2006 - 10.1103/PhysRevLett.97.216403
Physical review letters, Vol. 97, Issue 21 (November 2006) , p. 216403  

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