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1.
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22 p, 3.0 MB |
Genomic Validation of Endometrial Cancer Patient-Derived Xenograft Models as a Preclinical Tool
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Villafranca-Magdalena, Beatriz (Universitat Autònoma de Barcelona) ;
Masferrer-Ferragutcasas, Carina (Universitat Autònoma de Barcelona) ;
López-Gil, Carlos (Universitat Autònoma de Barcelona) ;
Coll de la Rubia, Eva (Universitat Autònoma de Barcelona) ;
Rebull, Marta (Universitat Autònoma de Barcelona) ;
Parra, Genis (Centre de Regulació Genòmica) ;
García, Ángel (Hospital Universitari Vall d'Hebron) ;
Reques, Armando (Hospital Universitari Vall d'Hebron) ;
Cabrera Díaz, Silvia (Vall d'Hebron Institut d'Oncologia) ;
Colás Ortega, Eva (Universitat Autònoma de Barcelona) ;
Gil-Moreno, Antonio 1965- (Vall d'Hebron Institut d'Oncologia) ;
Moiola, Cristian Pablo (Universitat Autònoma de Barcelona)
Endometrial cancer (EC) is the second most frequent gynecological cancer worldwide. Although improvements in EC classification have enabled an accurate establishment of disease prognosis, women with a high-risk or recurrent EC face a dramatic situation due to limited further treatment options. [...]
2022 -  10.3390/ijms23116266
International journal of molecular sciences, Vol. 23 (june 2022)
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2.
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16 p, 5.4 MB |
Intratumor genetic heterogeneity and clonal evolution to decode endometrial cancer progression
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Mota, Alba (Universidad Autónoma de Madrid. Departamento de Bioquímica) ;
Oltra, Sara S. (Centro de Investigación Biomédica en Red de Cáncer) ;
Selenica, Pier (Memorial Sloan Kettering Cancer Center) ;
Moiola, Cristian Pablo (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Casas-Arozamena, Carlos (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
López-Gil, Carlos (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Diaz, Eva (MD Anderson International Foundation) ;
Gatius, Sonia (Hospital Arnau de Vilanova (València)) ;
Ruiz-Miro, María (Biobank (Lleida)) ;
Calvo, Ana (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Rojo-Sebastián, Alejandro (MD Anderson Cancer Center) ;
Hurtado Blanco, P (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Piñeiro, Health Research Institute of Santiago de Compostela ;
Colás Ortega, Eva (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Gil-Moreno, Antonio 1965- (Hospital Universitari Vall d'Hebron) ;
Reis-Filho, Jorge S. (Memorial Sloan Kettering Cancer Center.) ;
Muinelo-Romay, Laura (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Abal Posada, Miguel (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Matias-Guiu, Xavier (Universitat de Lleida) ;
Weigelt, Britta (Memorial Sloan Kettering Cancer Center. Department of Pathology) ;
Moreno-Bueno, Gema (Centro de Investigación Biomédica en Red de Cáncer) ;
Universitat Autònoma de Barcelona
Analyzing different tumor regions by next generation sequencing allows the assessment of intratumor genetic heterogeneity (ITGH), a phenomenon that has been studied widely in some tumor types but has been less well explored in endometrial carcinoma (EC). [...]
2022 - 10.1038/s41388-022-02221-0
Oncogene, Vol. 41 (february 2022) , p. 1835-1850
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3.
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13 p, 2.0 MB |
Metabolomic and Lipidomic Profiling Identifies The Role of the RNA Editing Pathway in Endometrial Carcinogenesis
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Altadill, Tatiana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Dowdy, Tyrone M. (Georgetown University Medical Center) ;
Gill, Kirandeep (Georgetown University Medical Center) ;
Reques, Armando (Hospital Universitari Vall d'Hebron) ;
Menon, Smrithi S. (Georgetown University Medical Center) ;
Moiola, Cristian Pablo (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Lopez-Gil, Carlos (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Coll de la Rubia, Eva (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Matias-Guiu, Xavier (Institut d'Investigació Biomèdica de Bellvitge) ;
Cabrera Díaz, Silvia (Vall d'Hebron Institut d'Oncologia) ;
Garcia, Angel (Hospital Universitari Vall d'Hebron) ;
Reventos, Jaume (Universitat Internacional de Catalunya) ;
Byers, Stephen W. (Georgetown-Lombardi Comprehensive Cancer Center) ;
Gil-Moreno, Antonio 1965- (Vall d'Hebron Institut d'Oncologia) ;
Cheema, Amrita K. (Georgetown-Lombardi Comprehensive Cancer Center) ;
Colás Ortega, Eva (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
Endometrial cancer (EC) remains the most common malignancy of the genital tract among women in developed countries. Although much research has been performed at genomic, transcriptomic and proteomic level, there is still a significant gap in the metabolomic studies of EC. [...]
2017 - 10.1038/s41598-017-09169-2
Scientific reports, Vol. 7 (august 2017)
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4.
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26 p, 789.4 KB |
Small-Molecule Inhibitors (SMIs) as an Effective Therapeutic Strategy for Endometrial Cancer
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Megino-Luque, Cristina (Centro de Investigación Biomédica en Red de Cáncer) ;
Moiola, Cristian Pablo (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Molins-Escuder, Clara (Universitat de Lleida) ;
López-Gil, Carlos (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Gil-Moreno, Antonio 1965- (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Matias-Guiu, Xavier (Institut d'Investigació Biomèdica de Bellvitge) ;
Colás Ortega, Eva (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Eritja, Núria (Institut de Recerca Biomèdica de Lleida) ;
Universitat Autònoma de Barcelona
Patients diagnosed with endometrial cancer (EC), the most common gynaecological malignancy in women worldwide, cope with a disease associated with poor prognosis and limited treatment options after first-line therapy when it reaches an advanced or metastatic stage. [...]
2020 - 10.3390/cancers12102751
Cancers, Vol. 12 (september 2020)
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5.
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16 p, 3.4 MB |
Genomic Profiling of Uterine Aspirates and cfDNA as an Integrative Liquid Biopsy Strategy in Endometrial Cancer
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Casas-Arozamena, Carlos (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Diaz, Eva (Foundation MD Anderson International (Madrid)) ;
Moiola, Cristian Pablo (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Alonso-Alconada, Lorena (Nasasbiotech (La Coruña)) ;
Ferreiros, Alba (Nasasbiotech (La Coruña)) ;
Abalo, Alicia (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
López Gil, Carlos (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Oltra, Sara S. (Foundation MD Anderson International (Madrid)) ;
de Santiago, Javier (Department of Gynecology, MD Anderson Cancer Center, 28029 Madrid, Spain) ;
Cabrera Díaz, Silvia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Sampayo, Victoria (Complejo Hospitalario Universitario de Santiago de Compostela) ;
Bouso, Marta (Complejo Hospitalario Universitario de Santiago de Compostela) ;
Arias, Efigenia (Complejo Hospitalario Universitario de Santiago de Compostela) ;
Cueva, Juan (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Colás Ortega, Eva (Centro de Investigación Biomédica en Red de Cáncer) ;
Vilar, Ana (Complejo Hospitalario Universitario de Santiago de Compostela) ;
Gil-Moreno, Antonio 1965- (Centro de Investigación Biomédica en Red de Cáncer) ;
Abal Posada, Miguel (Centro de Investigación Biomédica en Red de Cáncer) ;
Moreno-Bueno, Gema (University of Madrid) ;
Muinelo-Romay, Laura (Centro de Investigación Biomédica en Red de Cáncer) ;
Universitat Autònoma de Barcelona
The incidence and mortality of endometrial cancer (EC) have risen in recent years, hence more precise management is needed. Therefore, we combined different types of liquid biopsies to better characterize the genetic landscape of EC in a non-invasive and dynamic manner. [...]
2020 - 10.3390/jcm9020585
Journal of clinical medicine, Vol. 9 (february 2020)
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6.
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10 p, 365.3 KB |
Hospital and 4-year mortality predictors in patients with acute pulmonary edema with and without coronary artery disease
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Figueras Bellot, Jaume (Hospital Universitari Vall d'Hebron) ;
Bañeras, Jordi (Hospital Universitari Vall d'Hebron) ;
Peña-Gil, Carlos (Complexo Hospitalario Universitario de Vigo) ;
Barrabés, José A (Hospital Universitari Vall d'Hebron) ;
Rodríguez Palomares, José Fernando (Hospital Universitari Vall d'Hebron) ;
García-Dorado, David (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona
Long-term prognosis of acute pulmonary edema () remains ill defined. We evaluated demographic, echocardiographic, and angiographic data of 806 consecutive patients with with () and without coronary artery disease (non-) admitted from 2000 to 2010. [...]
2016 - 10.1161/JAHA.115.002581
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol. 5, issue 2 (Feb. 2016)
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8.
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9.
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8 p, 493.8 KB |
Colangiocarcinoma en un hurón doméstico (Mustela putorius furo)
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Giner Audivert, Jacobo (Centro Veterinario Menescalia (Valencia)) ;
Martínez Gil, Carlos (Centro Veterinario Menescalia (Valencia))
Se describe el caso de una hurona esterilizada, de 4 años de edad, con historial previo de enteritis linfoplasmocitaria, colangitis linfocítica y quistes biliares. El examen clínico reveló, mediante palpación abdominal, la presencia de una masa bien delimitada en abdomen craneal. [...]
2012
Clínica veterinaria de pequeños animales, Vol. 32 Núm. 3 (2012) , p. 181-187
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