Resultats globals: 5 registres trobats en 0.02 segons.
Articles, 5 registres trobats
Articles 5 registres trobats  
1.
22 p, 1.4 MB Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers / Jansen, Iris (Vrije Universiteit Amsterdam) ; van der Lee, Sven J (Vrije Universiteit Amsterdam) ; Gomez-Fonseca, Duber (Washington University School of Medicine) ; De Rojas, Itziar (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Dalmasso, Maria Carolina (Neurosciences and Complex Systems Unit (ENyS). CONICET. Hospital El Cruce. National University A. Jauretche (UNAJ)) ; Grenier-Boley, Benjamin (Université de Lille) ; Zettergren, Anna (University of Gothenburg) ; Mishra, Aniket (Université de Bordeaux) ; Ali, Muhammad (Washington University School of Medicine) ; Andrade, Victor (University Hospital Bonn. Medical Faculty) ; Bellenguez, Céline (Université de Lille) ; Kleineidam, Luca (German Center for Neurodegenerative Diseases (DZNE)) ; Küçükali, Fahri (University of Antwerp. Department of Biomedical Sciences) ; Sung, Ju Sung (Washington University School of Medicine) ; Tesí, Niccolo (Vrije Universiteit Amsterdam) ; Vromen, Ellen (Amsterdam Neuroscience. Neurodegeneration) ; Wightman, Douglas P (Vrije Universiteit Amsterdam) ; Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ; Alegret, Montserrat (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Alvarez, Ignacio (Fundació per a la Recerca Biomèdica i Social Mútua de Terrassa) ; Amouyel, Philippe (Université de Lille) ; Athanasiu, Lavinia (NORMENT Centre. Institute of Clinical Medicine. University of Oslo and Division of Mental Health) ; Bahrami, Shahram (NORMENT Centre. Institute of Clinical Medicine. University of Oslo and Division of Mental Health) ; Bailly, Henri (Université Paris Cité) ; Belbin, Olivia (Institut d'Investigació Biomèdica Sant Pau) ; Bergh, Sverre (Vestfold Hospital Trust) ; Bertram, Lars (University of Lübeck) ; Biessels, Geert Jan (UMC Utrecht Brain Center) ; Blennow, Kaj (Sahlgrenska University Hospital (Suècia)) ; Blesa, Rafael (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ; Boada, Mercè (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Boland, Anne (Université Paris-Saclay. Centre National de Recherche en Génomique Humaine) ; Buerger, K. (Institute for Stroke and Dementia Research (ISD). University Hospital. LMU Munich) ; Carracedo, Ángel (Fundación Pública Galega de Medicina Xenómica-CIBERER-IDIS) ; Cervera Carles, Laura (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ; Chene, Geneviève (Department of Neurology. CHU de Bordeaux) ; Claassen, Jurgen (Donders Center for Medical Neuroscience) ; Debette, Stephanie (University School of Medicine) ; Deleuze, Jean‑Francois (Université Paris-Saclay. Centre National de Recherche en Génomique Humaine) ; De Deyn, Peter Paul (University Medical Center Groningen. Department of Neurology and Alzheimer Center Groningen.) ; Diehl-Schmid, Janine (kbo-Inn-Salzach-Hospital) ; Djurovic, Srdjan (University of Bergen. Department of Clinical Science. NORMENT Centre.) ; Dols Icardo, Oriol (Institut d'Investigació Biomèdica Sant Pau) ; Dufouil, Carole (Pôle de Santé Publique) ; Duron, Emmanuelle (Univerisité Paris-Saclay) ; Düzel, Emrah (Otto-von-Guericke University Magdeburg. Institute of Cognitive Neurology and Dementia Research) ; Fladby, Tormod (Akershus University Hospital. Department of Neurology.) ; Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau) ; Frölich, Lutz (Medical Faculty Mannheim. Department of Geriatric Psychiatry. Central Institute of Mental Health.) ; García-González, Pablo (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Garcia-Martinez, María (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ; Giegling, Ina (Medical University of Vienna) ; Goldhardt, Oliver (Technical University of Munich) ; Gobom, Johan (Sahlgrenska University Hospital (Suècia)) ; Grimmer, Timo (Technical University of Munich) ; Haapasalo, Annakaisa (University of Eastern Finland A.I. Virtanen Institute for Molecular Sciences) ; Hampel, Harald (Neurology Business Group. Eisai Inc) ; Hanon, Olivier (Service gériatrie. Centre Mémoire de Ressources et Recherches Ile de France-Broca. AP-HP. Hôpital Broca) ; Hausner, Lucrezia (Central Institute of Mental Health. Department of Geriatric Psychiatry) ; Heilmann-Heimbach, Stefanie (Institute of Human Genetics. University of Bonn. School of Medicine and University Hospital Bonn) ; Helisalmi, Seppo (University of Eastern Finland. Institute of Clinical Medicine) ; Heneka, Michael (German Center for Neurodegenerative Diseases (DZNE)) ; Hernández, Isabel (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Herukka, Sanna‑Kaisa (University of Eastern Finland. Department of Neurology. Institute of Clinical Medicine) ; Holstege, Henne (Vrije Universiteit Amsterdam. Section Genomics of Neurodegenerative Diseases and Aging) ; Jarholm, Jonas (Akershus University Hospital. Department of Neurology.) ; Kern, Silke (Sahlgrenska University Hospital. Psychiatry. Cognition and Old Age Psychiatry Clinic) ; Knapskog, Anne‑Brita (Oslo University Hospital. Department of Geriatric Medicine) ; Koivisto, A.M. (Department of Neurology. Helsinki University Hospital) ; Kornhuber, Johannes (Friedrich-Alexander Universität Erlangen-Nürnberg) ; Kuulasmaa, Teemu (University of Eastern Finland) ; Lage, Carmen (University of California) ; Laske, Christoph (University of Tübingen. Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy.) ; Leinonen, Ville (Kuopio University Hospita. Department of Neurosurgery.) ; Lewczuk, Piotr (Medical University of Białystok. Department of Neurodegeneration Diagnostics.) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; López de Munain, Adolfo (University of The Basque Country) ; López-Garcia, Sara (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ; Maier, Wolfgang (University Hospital Bonn. Department of Neurodegenerative Diseases and Geriatric Psychiatry) ; Marquié, Marta (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Mol, Merel O. (Erasmus Medical Centre. Department of Neurology) ; Montrreal, Laura (Universitat Internacional de Catalunya. Ace Alzheimer Center Barcelona) ; Moreno, Fermin (Biodonostia Osasun Ikerketako Institutura (País Basc)) ; Moreno-Grau, Sonia (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Nicolas, Gael (Normandie Univ. UNIROUEN. Department of Genetics and CNR-MAJ) ; Nöthen, Markus M. (Institute of Human Genetics. University of Bonn. School of Medicine and University Hospital Bonn) ; Orellana, Adelina (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Pålhaugen, Lene (Akershus University Hospital. Department of Neurology) ; Papma, Janne M. (Erasmus MC University Medical Center. Department of Neurology and Alzheimer Center Erasmus MC) ; Pasquier, Florence (Université Lille) ; Perneczky, Robert (Imperial College London. Ageing Epidemiology Research Unit) ; Peters, Oliver (German Center for Neurodegenerative Diseases (DZNE)) ; Pijnenburg, Yolande A.L. (Amsterdam Neuroscience. Neurodegeneration) ; Popp, Julius (University Hospital of Lausanne. Department of Psychiatry) ; Posthuma, Danielle (Vrije Universiteit Amsterdam) ; Pozueta, Ana (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ; Priller, Josef (Technical University Munich. Department of Psychiatry and Psychotherapy) ; Puerta, Raquel (Universitat Internacional de Catalunya. Ace Alzheimer Center Barcelona) ; Quintela, Inés (Grupo de Medicina Xenómica. Centro Nacional de Genotipado (CEGEN-PRB3-ISCIII). Universidade de Santiago de Compostela) ; Ramakers, Inez (Maastricht University. Department of Psychiatry and Neuropsychologie) ; Rodríguez-Rodríguez, Eloy (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ; Rujescu, Dan (Medical University of Vienna. Department of Psychiatry and Psychotherapy) ; Saltvedt, Ingvild (University Hospital of Trondheim. Department of Geriatrics) ; Sánchez-Juan, Pascual (Alzheimer's Centre Reina Sofia-CIEN Foundation-ISCIII) ; Scheltens, Philip (Amsterdam Neuroscience. Neurodegeneration) ; Scherbaum, Norbert (University of Duisburg-Essen) ; Schmid, Matthias (University Hospital of Bonn. Institute of Medical Biometry) ; Schneider, Anja (German Center for Neurodegenerative Diseases (DZNE)) ; Selbæk, Geir (Oslo University Hospital.Department of Geriatric Medicine) ; Selnes, Per (Akershus University Hospital. Department of Neurology) ; Shadrin, Alexey (University of Oslo and Division of Mental Health. Institute of Clinical Medicine) ; Skoog, Ingmar (Sahlgrenska University Hospital (Suècia)) ; Soininen, Hilkka (University of Eastern Finland. Institute of Clinical Medicine.) ; Tárraga, Lluís (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Teipel, Stefan (Rostock University Medical Center. Department of Psychosomatic Medicine) ; Tijms, Betty M (Amsterdam Neuroscience. Neurodegeneration) ; Tsolaki, Magda (Aristotle University of Thessaloniki) ; Van Broeckhoven, Christine (Neurodegenerative Brain Diseases Group. VIB Center for Molecular Neurology. VIB) ; Van Dongen, Jasper (University of Antwerp. Department of Biomedical Sciences) ; van Swieten, John C. (Erasmus MC University Medical Center) ; Vandenberghe, Rik (Leuven Brain Institute. Department of Neurosciences.) ; Vidal, Jean‑Sébastien (Université Paris Cité) ; Visser, Pieter J. (Division of Neurogeriatrics Karolinska Institutet. Department of Neurobiology) ; Vogelgsang, Jonathan (Harvard Medical School. Department of Psychiatry) ; Waern, Margda (Sahlgrenska University Hospital (Suècia)) ; Wagner, Michael (German Center for Neurodegenerative Diseases (DZNE)) ; Wiltfang, Jens W (Medical Science Department. iBiMED) ; Wittens, Mandy M.J. (Vrije Universiteit Brussel) ; Zetterberg, Henrik (Hong Kong Center for Neurodegenerative Diseases) ; Zulaica, Miren (Biodonostia Osasun Ikerketako Institutura (País Basc)) ; van Duijn, Cornelia M. (Nuffield Department of Population Health. Oxford University) ; Bjerke, Maria (Universitair Ziekenhuis Brussel) ; Engelborghs, Sebastiaan (Universitair Ziekenhuis Brussel. Department of Neurology) ; Jessen, Frank (University of Cologne) ; Teunissen, Charlotte E. (Vrije Universiteit Amsterdam) ; Pastor, Pau (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Hiltunen, Mikko (University of Eastern Finland. Institute of Biomedicine) ; Ingelsson, Martin (University of Toronto. Department of Medicine) ; Andreassen, Ole A (Oslo University Hospital (Oslo, Noruega)) ; Clarimón, Jordi (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ; Sleegers, Kristel (University of Antwerp. Department of Biomedical Sciences) ; Ruiz, Agustín (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Ramirez, Alfredo (Department of Psychiatry. Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases) ; Cruchaga, Carlos (Washington University School of Medicine. Hope Center for Neurological Disorders) ; Lambert, Jean-Charles (Institut Pasteur de Lille) ; van der Flier, Wiesje M (Amsterdam Neuroscience. Neurodegeneration) ; Universitat Autònoma de Barcelona
Amyloid-beta 42 (Aβ42) and phosphorylated tau (pTau) levels in cerebrospinal fluid (CSF) reflect core features of the pathogenesis of Alzheimer's disease (AD) more directly than clinical diagnosis. Initiated by the European Alzheimer & Dementia Biobank (EADB), the largest collaborative effort on genetics underlying CSF biomarkers was established, including 31 cohorts with a total of 13,116 individuals (discovery n = 8074; replication n = 5042 individuals). [...]
2022 - 10.1007/s00401-022-02454-z
Acta Neuropathologica, Vol. 144 Núm. 5 (november 2022) , p. 821-842  
2.
13 p, 1.3 MB Validation of the LUMIPULSE automated immunoassay for the measurement of core AD biomarkers in cerebrospinal fluid / Gobom, Johan (Clinical Neurochemistry Laboratory. Sahlgrenska University Hospital) ; Parnetti, Lucilla (Laboratory of Clinical Neurochemistry. Section of Neurology. University of Perugia) ; Rosa-Neto, Pedro (Montreal Neurological Institute) ; Vyhnalek, Martin (International Clinical Research Center. St. Anne's University Hospital) ; Gauthier, Serge (Montreal Neurological Institute) ; Cataldi, Samuela (Laboratory of Clinical Neurochemistry. Section of Neurology. University of Perugia) ; Lerch, Ondrej (International Clinical Research Center. St. Anne's University Hospital) ; Laczo, Jan (International Clinical Research Center. St. Anne's University Hospital) ; Cechova, Katerina (International Clinical Research Center. St. Anne's University Hospital) ; Clarin, Marcus (Clinical Neurochemistry Laboratory. Sahlgrenska University Hospital) ; Benet, Andrea L. (Translational Neuroimaging Laboratory. McGill Centre for Studies in Aging. McGill University) ; Pascoal, Tharick A. (Translational Neuroimaging Laboratory. McGill Centre for Studies in Aging. McGill University) ; Rahmouni, Neserine (Translational Neuroimaging Laboratory. McGill Centre for Studies in Aging. McGill University) ; Vandijck, Manu (Fujirebio Europe N.V.) ; Huyck, Else (Fujirebio Europe N.V.) ; Le Bastard, Nathalie (Fujirebio Europe N.V.) ; Stevenson, Jenna (Translational Neuroimaging Laboratory. McGill Centre for Studies in Aging. McGill University) ; Chamoun, Mira (Translational Neuroimaging Laboratory. McGill Centre for Studies in Aging. McGill University) ; Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Andreasson, Ulf (Clinical Neurochemistry Laboratory. Sahlgrenska University Hospital) ; Verbeek, Marcel M. (Department of Neurology. Radboud Alzheimer Centre. Radboud University Medical Center. Donders Institute for Brain. Cognition and Behaviour) ; Bellomo, Giovanni (Laboratory of Clinical Neurochemistry. Section of Neurology. University of Perugia) ; Rinaldi, Roberta (Laboratory of Clinical Neurochemistry. Section of Neurology. University of Perugia) ; Ashton, Nicholas J. (NIHR Biomedical Research Centre for Mental Health and Biomedical Research Unit for Dementia at South London and Maudsley NHS Foundation) ; Zetterberg, Henrik (UCL Institute of Neurology (Regne Unit). UK Dementia Research Institute) ; Sheardova, Katerina (First Department of Neurology. Faculty of Medicine. Masaryk University. St. Anne's University Hospital) ; Hort, Jakub (First Department of Neurology. Faculty of Medicine. Masaryk University. St. Anne's University Hospital) ; Blennow, Kaj (Clinical Neurochemistry Laboratory. Sahlgrenska University Hospital) ; Universitat Autònoma de Barcelona
Objectives: The core cerebrospinal fluid (CSF) biomarkers; total tau (tTau), phospho-tau (pTau), amyloid β 1-42 (Aβ 1-42), and the Aβ 1-42/Aβ 1-40 ratio have transformed Alzheimer's disease (AD) research and are today increasingly used in clinical routine laboratories as diagnostic tools. [...]
2022 - 10.1515/cclm-2021-0651
Clinical Chemistry and Laboratory Medicine, Vol. 60 Núm. 2 (january 2022) , p. 207-219  
3.
16 p, 2.1 MB Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer's disease / Visser, Pieter Jelle (Karolinska Institutet (Estocolm, Suècia)) ; Reus, Lianne M. (Vrije Universiteit Amsterdam) ; Gobom, Johan (Sahlgrenska Academy at the University of Gothenburg) ; Jansen, Iris E (VU University) ; Dicks, Ellen (Vrije Universiteit Amsterdam) ; van der Lee, Sven J. (Vrije Universiteit Amsterdam) ; Tsolaki, Magda (AHEPA University Hospital (Grècia)) ; Verhey, Frans R. J. (Maastricht University) ; Popp, Julius (University Hospital Zurich (Suïssa)) ; Martinez-Lage, Pablo (Fundación CITA-Alzhéimer Fundazioa) ; Vandenberghe, Rik (KU Leuven) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Molinuevo, José Luís (Hospital Clínic i Provincial de Barcelona) ; Engelborghs, Sebastiaan (Vrije Universiteit Brussel) ; Freund-Levi, Yvonne (Örebro University) ; Froelich, Lutz (University of Heidelberg) ; Sleegers, Kristel (University of Antwerp) ; Dobricic, Valerija (University of Lübeck) ; Lovestone, Simon (High Wycombe, UK) ; Streffer, Johannes (AC Immune SA) ; Vos, Stephanie J. B. (Maastricht University) ; Bos, Isabelle (Maastricht University) ; Smit, August B. (Vrije Universiteit Amsterdam) ; Blennow, Kaj (Sahlgrenska Academy at the University of Gothenburg) ; Scheltens, Philip (Vrije Universiteit Amsterdam) ; Teunissen, Charlotte E. (Amsterdam University Medical Centers (AUMC)) ; Bertram, Lars (University of Oslo) ; Zetterberg, Henrik (Dementia Research Institute at UCL) ; Tijms, Betty M. (Vrije Universiteit Amsterdam) ; Universitat Autònoma de Barcelona
Increased total tau (t-tau) in cerebrospinal fluid (CSF) is a key characteristic of Alzheimer's disease (AD) and is considered to result from neurodegeneration. T-tau levels, however, can be increased in very early disease stages, when neurodegeneration is limited, and can be normal in advanced disease stages. [...]
2022 - 10.1186/s13024-022-00521-3
Molecular neurodegeneration, Vol. 17 (march 2022)  
4.
15 p, 1.5 MB CSF Proteomic Alzheimer's Disease-Predictive Subtypes in Cognitively Intact Amyloid Negative Individuals / Tijms, Betty Marije (Amsterdam UMC) ; Gobom, Johan (University of Gothenburg) ; Teunissen, Charlotte E (Amsterdam UMC. University Medical Center) ; Dobricic, Valerija (University of Lübeck) ; Tsolaki, Magda (AHEPA University Hospital (Grècia)) ; Verhey, Frans (Maastricht University) ; Popp, Julius (University of Zürich) ; Martinez-Lage, Pablo (Fundación CITA-Alzhéimer Fundazioa) ; Vandenberghe, Rik (KU Leuven. Department of Neurosciences) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Molinuevo, José Luis (Hospital Clínic i Provincial de Barcelona) ; Engelborghs, Sebastiaan (Universitair Ziekenhuis Brussel) ; Freund-Levi, Yvonne (Karolinska Institutet (Estocolm, Suècia). Department of Neurobiology, Care Sciences and Society) ; Froelich, Lutz (University of Heidelberg. Department of Geriatric Psychiatry) ; Bertram, Lars (University of Oslo. Department of Psychology) ; Lovestone, Simon (University of Oxford) ; Streffer, Johannes (AC Immune SA) ; Vos, Stephanie (Maastricht University) ; Blennow, Kaj (University of Gothenburg) ; Scheltens, Philip (Amsterdam UMC) ; Zetterberg, Henrik (UCL Institute of Neurology (Regne Unit). UK Dementia Research Institute) ; Visser, Pieter Jelle (Karolinska Institutet (Estocolm, Suècia). Department of Neurobiology, Care Sciences and Society) ; Universitat Autònoma de Barcelona
We recently discovered three distinct pathophysiological subtypes in Alzheimer's disease (AD) using cerebrospinal fluid (CSF) proteomics: one with neuronal hyperplasticity, a second with innate immune system activation, and a third subtype with blood-brain barrier dysfunction. [...]
2021 - 10.3390/proteomes9030036
Proteomes, Vol. 9 (august 2021)  
5.
17 p, 1.3 MB Pathophysiological subtypes of Alzheimer's disease based on cerebrospinal fluid proteomics / Tijms, Betty M. (Vrije Universiteit Amsterdam) ; Gobom, Johan (Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg) ; Reus, Lianne (Vrije Universiteit Amsterdam) ; Jansen, Iris E (Vrije Universiteit Amsterdam) ; Hong, Shengjun (Lübeck Interdisciplinary Platform for Genome Analytics (LIGA), Institutes of Neurogenetics and Cardiogenetics, University of Lübeck) ; Dobricic, Valerija (Lübeck Interdisciplinary Platform for Genome Analytics (LIGA), Institutes of Neurogenetics and Cardiogenetics, University of Lübeck) ; Kilpert, Fabian (Lübeck Interdisciplinary Platform for Genome Analytics (LIGA), Institutes of Neurogenetics and Cardiogenetics, University of Lübeck) ; ten Kate, Mara (Vrije Universiteit Amsterdam) ; Barkhof, Frederik (Institutes of Neurology and Healthcare Engineering, UCL London) ; Tsolaki, Magda (AHEPA University Hospital (Grècia)) ; Verhey, Frans R. J. (Alzheimer Center Limburg, School for Mental Health and Neuroscience, Maastricht University) ; Popp, Julius (Geneva University Hospitals (Suïssa)) ; Martinez-Lage, Pablo (Fundación CITA-Alzhéimer Fundazioa) ; Vandenberghe, Rik (Laboratory for Cognitive Neurology, Department of Neurosciences, KU Leuven) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Molinuevo, José Luís (Hospital Clínic i Provincial de Barcelona) ; Engelborghs, Sebastiaan (Department of Neurology, UZ Brussel and Center for Neurosciences (C4N), Vrije Universiteit Brussel (VUB)) ; Bertram, Lars (Lübeck Interdisciplinary Platform for Genome Analytics (LIGA), Institutes of Neurogenetics and Cardiogenetics, University of Lübeck) ; Lovestone, Simon (Janssen R&D) ; Streffer, Johannes (UCB Biopharma SPRL) ; Vos, Stephanie (Alzheimer Center Limburg, School for Mental Health and Neuroscience, Maastricht University) ; Bos, Isabelle (Alzheimer Center Limburg, School for Mental Health and Neuroscience, Maastricht University) ; Blennow, Kaj (Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg) ; Scheltens, Philip (Vrije Universiteit Amsterdam) ; Teunissen, Charlotte E. (Neurochemistry laboratory, Department of Clinical Chemistry, Amsterdam UMC - location VUmc, Amsterdam Neuroscience) ; Zetterberg, Henrik (UCL Institute of Neurology (Regne Unit). UK Dementia Research Institute) ; Visser, Pieter Jelle (Karolinska Institutet (Estocolm, Suècia). Department of Neurobiology, Care Sciences and Society) ; Universitat Autònoma de Barcelona
Using CSF proteomics, Tijms et al. identify three Alzheimer's disease subtypes that show: 1) hyperplasticity and increased BACE1 levels; 2) innate immune activation; and 3) blood-brain barrier dysfunction with low BACE1 levels. [...]
2020 - 10.1093/brain/awaa325
Brain, Vol. 143 (november 2020) , p. 3776-3792  

Vegeu també: autors amb noms similars
1 Gobom, J.
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