Resultats globals: 5 registres trobats en 0.01 segons.
Articles, 5 registres trobats
Articles 5 registres trobats  
1.
23 p, 1.5 MB The Role of Purported Mucoprotectants in Dealing with Irritable Bowel Syndrome, Functional Diarrhea, and Other Chronic Diarrheal Disorders in Adults / Alonso Cotoner, Carmen (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ; Abril-Gil, Mar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Albert-Bayo, Mercé (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Mall, John-P. Ganda (Linköping University. Department of Biomedical and Clinical Sciences) ; Expósito, Elba (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; González-Castro, Ana María (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Lobo, Beatriz (Universitat Autònoma de Barcelona. Facultat de Medicina) ; Santos, Javier (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas)
Chronic diarrhea is a frequent presenting symptom, both in primary care medicine and in specialized gastroenterology units. It is estimated that more than 5% of the global population suffers from chronic diarrhea. [...]
2021 - 10.1007/s12325-021-01676-z
Advances in Therapy, march 2021, p. 1-23  
2.
11 p, 484.9 KB Increased Colonic Epithelial Permeability and Mucosal Eosinophilia in Ulcerative Colitis in Remission Compared With Irritable Bowel Syndrome and Health / Katinios, Georgios (Department of Biomedical and Clinical Sciences, Linköping University) ; Casado Bedmar, María Teresa (Department of Biomedical and Clinical Sciences, Linköping University) ; Walter, Susanna A (Department of Biomedical and Clinical Sciences, Linköping University) ; Vicario Perez, Maria (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; González-Castro, Ana María (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Bednarska, Olga (Department of Biomedical and Clinical Sciences, Linköping University) ; Söderholm, Johan D (Department of Surgery, Linköping, Linköping University) ; Hjortswang, Henrik (Department of Biomedical and Clinical Sciences, Linköping University) ; Keita, Åsa V (Department of Biomedical and Clinical Sciences, Linköping University) ; Universitat Autònoma de Barcelona
Barrier dysfunction is recognized as a pathogenic factor in ulcerative colitis (UC) and irritable bowel syndrome (IBS), but it is unclear to what extent the factors related to barrier dysfunction are disease-specific. [...]
2020 - 10.1093/ibd/izz328
Inflammatory Bowel Diseases, Vol. 26 (january 2020) , p. 974-984  
3.
24 p, 1.4 MB Intestinal mucosal mast cells : key modulators of barrier function and homeostasis / Albert-Bayo, Mercé (Hospital Universitari Vall d'Hebron) ; Paracuellos, Irene (Hospital Universitari Vall d'Hebron) ; González-Castro, Ana María (Hospital Universitari Vall d'Hebron) ; Rodríguez-Urrutia, Amanda (Universitat Autònoma de Barcelona) ; University of Barcelona ; Alonso Cotoner, Carmen (Hospital Universitari Vall d'Hebron) ; Santos, Javier (Hospital Universitari Vall d'Hebron) ; Vicario Perez, Maria (Hospital Universitari Vall d'Hebron. Institut de Recerca)
The gastrointestinal tract harbours the largest opulation of mast cells in the body; this highly specialised leukocyte cell type is able to adapt its phenotype and function to the microenvironment in which it resides. [...]
2019 - 10.3390/cells8020135
Cells, Vol. 8 (2019) , p. 1-24  
4.
11 p, 2.3 MB Decreased TESK1-mediated cofilin 1 phosphorylation in the jejunum of IBS-D patients may explain increased female predisposition to epithelial dysfunction / Rodiño-Janeiro, Bruno K. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Martínez, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Fortea, Marina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Lobo Álvarez, Beatriz (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Pigrau Pastor, Marc (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Nieto, Adoración (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; González-Castro, Ana María (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Salvo Romero, Eloísa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Guagnozzi, Danila (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Pardo-Camacho, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Iribarren, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Azpiroz Vidaur, Fernando (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Alonso Cotoner, Carmen (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Santos, Javier (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Vicario Perez, Maria (Hospital Universitari Vall d'Hebron. Institut de Recerca)
Disturbed intestinal epithelial barrier and mucosal micro-inflammation characterize irritable bowel syndrome (IBS). Despite intensive research demonstrating ovarian hormones modulation of IBS severity, there is still limited knowledge on the mechanisms underlying female predominance in this disorder. [...]
2018 - 10.1038/s41598-018-20540-9
Scientific reports (Nature Publishing Group), Vol. 8 (2018) , art. 2255  
5.
14 p, 2.6 MB miR-16 and miR-125b are involved in barrier function dysregulation through the modulation of claudin-2 and cingulin expression in the jejunum in IBS with diarrhoea / Martínez, Cristina (Hospital Universitari Vall d'Hebron) ; Rodiño-Janeiro, Bruno K (Hospital Universitari Vall d'Hebron) ; Lobo, Beatriz (Hospital Universitari Vall d'Hebron) ; Stanifer, Megan L (University of Heidelberg) ; Klaus, Bernd (European Molecular Biology Laboratory (EMBL)) ; Granzow, Martin (Institute of Human Genetics, University of Heidelberg) ; González-Castro, Ana María (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Salvo-Romero, Eloisa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Alonso-Cotoner, Carmen (COST Action BM1106 Genes in Irritable Bowel Syndrome (GENIEUR) European Research Network) ; Pigrau Pastor, Marc (Hospital Universitari Vall d'Hebron) ; Roeth, Ralph (nCounter Core Facility, Institute of Human Genetics, University of Heidelberg) ; Rappold, Gudrun (Institute of Human Genetics, University of Heidelberg) ; Huber, Wolfgang (European Molecular Biology Laboratory (EMBL)) ; González-Silos, Rosa (Institute of Medical Biometry and Informatics, University of Heidelberg) ; Lorenzo, Justo (Institute of Medical Biometry and Informatics, University of Heidelberg) ; Torres, Inés de (Hospital Universitari Vall d'Hebron) ; Azpiroz Vidaur, Fernando (COST Action BM1106 Genes in Irritable Bowel Syndrome (GENIEUR) European Research Network) ; Boulant, Steeve (Research Group 'Cellular Polarity and Viral Infection' (F140), German Cancer Research Center (DKFZ)) ; Vicario, María (COST Action BM1106 Genes in Irritable Bowel Syndrome (GENIEUR) European Research Network) ; Niesler, Beate (nCounter Core Facility, Institute of Human Genetics, University of Heidelberg) ; Santos, Javier (COST Action BM1106 Genes in Irritable Bowel Syndrome (GENIEUR) European Research Network)
Micro-RNAs (miRNAs) play a crucial role in controlling intestinal epithelial barrier function partly by modulating the expression of tight junction (TJ) proteins. We have previously shown differential messenger RNA (mRNA) expression correlated with ultrastructural abnormalities of the epithelial barrier in patients with diarrhoea-predominant IBS (IBS-D). [...]
2017 - 10.1136/gutjnl-2016-311477
Gut, Vol. 66 (january 2017) , p. 1537-1538  

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