González-Sánchez, Elena - Search Results - UAB Digital Repository of Documents

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Articles, 2 records found Research literature, 1 records found

Articles	2 records found

8 p, 3.1 MB

Lkb1 Loss Promotes Tumor Progression of BRAF V600E -Induced Lung Adenomas / González-Sánchez, Elena (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Martín-Caballero, Juan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Flores, Juana María (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Hernandez-Losa, Javier (Hospital Universitari Vall d'Hebron) ; Cortés, Javier (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Marés, Roso (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Barbacid, Mariano (Centro Nacional de Investigaciones Oncológicas) ; Recio Conde, Juan Ángel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Aberrant activation of MAP kinase signaling pathway and loss of tumor suppressor LKB1 have been implicated in lung cancer development and progression. Although oncogenic KRAS mutations are frequent, BRAF mutations (BRAF V600E) are found in 3% of human non-small cell lung cancers. [...]
2013 - DOI (Digital Object Identifier)

10.1371/journal.pone.0066933
PloS one, Vol. 8 (june 2013)

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14 p, 4.2 MB

STK11 (LKB1) missense somatic mutant isoforms promote tumor growth, motility and inflammation / Granado-Martínez, Paula (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Garcia-Ortega, Sara (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; González-Sánchez, Elena (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; McGrail, Kimberley (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Selgas, Rafael (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Grueso, Judit (Vall d'Hebron Institut d'Oncologia) ; Gil, Rosa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Naldaiz-Gastesi, Neia (Present Address: Biodonostia, Neurosciences Area, Group of Neuromuscular Diseases) ; Rhodes, Ana C. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Hernandez-Losa, Javier (Hospital Universitari Vall d'Hebron) ; Ferrer, Berta (Hospital Universitari Vall d'Hebron) ; Canals, Francesc (Vall d'Hebron Institut d'Oncologia) ; Villanueva, Josep (Vall d'Hebron Institut d'Oncologia) ; Méndez Fernández, Olga (Vall d'Hebron Institut d'Oncologia) ; Espinosa-Gil, Sergio (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Lizcano de Vega, José Miguel (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Muñoz Couselo, Eva (Vall d'Hebron Institut d'Oncologia) ; García-Patos Briones, Vicente (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Recio Conde, Juan Ángel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Elucidating the contribution of somatic mutations to cancer is essential for personalized medicine. STK11 (LKB1) appears to be inactivated in human cancer. However, somatic missense mutations also occur, and the role/s of these alterations to this disease remain unknown. [...]
2020 - DOI (Digital Object Identifier)

10.1038/s42003-020-1092-0
Communications Biology, Vol. 3 (july 2020)

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Research literature	1 records found

105 p, 3.8 MB

Study of the cooperative effect of UVR, BRAF and LKB1 in melanoma / González-Sánchez, Elena ; Recio Conde, Juan Ángel, dir. ; Lizcano de Vega, José Miguel, dir. ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular
Entender los mecanismos moleculares relacionados con la melanomagénesis es clave a la hora de encontrar nuevas estrategias preventivas y terapéuticas contra esta letal enfermedad. La epidemiología indica que hay factores genéticos y medioambientales asociados con el desarrollo y la progresión del melanoma. [...]
Understanding the molecular mechanisms related with melanomagenesis is key in order to find new preventive and therapeutical approaches against this lethal disease. Epidemiology indicates that there are genetic- and environmental-factors associated with melanoma development and progression. [...]
[Barcelona] : Universitat Autònoma de Barcelona, 2019.

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See also: similar author names
1	González-Sánchez, Erika

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