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13 p, 3.8 MB |
Cortical microstructure in primary progressive aphasia : a multicenter study
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Illán-Gala, Ignacio (Institut d'Investigació Biomèdica Sant Pau) ;
Montal, Victor (Institut d'Investigació Biomèdica Sant Pau) ;
Borrego-Écija, Sergi (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Mandelli, Maria Luisa (University of California. Memory and Aging Center) ;
Falgàs, Neus (University of California. Memory and Aging Center) ;
Welch, Ariane E. (University of California. Memory and Aging Center) ;
Pegueroles, Jordi (Institut d'Investigació Biomèdica Sant Pau) ;
Santos-Santos, Miguel Angel (Institut d'Investigació Biomèdica Sant Pau) ;
Bejanin, Alexandre (Institut d'Investigació Biomèdica Sant Pau) ;
Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ;
Dols Icardo, Oriol (Institut d'Investigació Biomèdica Sant Pau) ;
Belbin, Olivia (Institut d'Investigació Biomèdica Sant Pau) ;
Sánchez-Saudinós, María Belén (Institut d'Investigació Biomèdica Sant Pau) ;
Bargalló, Núria (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
González-Ortiz, Sofía (Hospital del Mar (Barcelona, Catalunya)) ;
Lladó, Albert (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Blesa, Rafael (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Dickerson, Bradford C. (Massachusetts Alzheimer's Disease Research Center) ;
Rosen, Howard J. (University of California. Memory and Aging Center) ;
Miller, Bruce L. (University of California, San Francisco (UCSF)) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Gorno-Tempini, Maria Luisa (University of California. Department of Neurology) ;
Sanchez-Valle, Raquel (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau)
Background: Cortical mean diffusivity is a novel imaging metric sensitive to early changes in neurodegenerative syndromes. Higher cortical mean diffusivity values reflect microstructural disorganization and have been proposed as a sensitive biomarker that might antedate macroscopic cortical changes. [...]
2022 -  10.1186/s13195-022-00974-0
Alzheimer's research & therapy, Vol. 14 Núm. 1 (december 2022) , p. 27
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2.
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16 p, 2.1 MB |
Diagnostic Accuracy of Magnetic Resonance Imaging Measures of Brain Atrophy Across the Spectrum of Progressive Supranuclear Palsy and Corticobasal Degeneration
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Illán-Gala, Ignacio (Institut d'Investigació Biomèdica Sant Pau) ;
Nigro, Salvatore (Institute of Nanotechnology. National Research Council) ;
Vandevrede, Lawren (Memory and Aging Center. Department of Neurology. University of California) ;
Falgàs, Neus (Memory and Aging Center. Department of Neurology. University of California) ;
Heuer, Hilary W. (Memory and Aging Center. Department of Neurology. University of California) ;
Painous, Cèlia (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Compta, Yaroslau (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Martí, Maria J. (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Montal, Victor (Institut d'Investigació Biomèdica Sant Pau) ;
Pagonabarraga Mora, Javier (Institut d'Investigació Biomèdica Sant Pau) ;
Kulisevsky, Jaime (Institut d'Investigació Biomèdica Sant Pau) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau) ;
Logroscino, Giancarlo (Department of Basic Medicine. Neuroscience. and Sense Organs. University of Bari Aldo Moro) ;
Quattrone, Andrea (Neuroimaging Research Unit. Institute of Molecular Bioimaging and Physiology. National Research Council) ;
Perry, David C. (Memory and Aging Center. Department of Neurology. University of California) ;
Gorno-Tempini, Maria Luisa (Memory and Aging Center. Department of Neurology. University of California) ;
Rosen, Howard J. (Memory and Aging Center. Department of Neurology. University of California) ;
Grinberg, Lea T. (Memory and Aging Center. Department of Neurology. University of California) ;
Spina, Salvatore (Memory and Aging Center. Department of Neurology. University of California) ;
La Joie, Renaud (Memory and Aging Center. Department of Neurology. University of California) ;
Rabinovici, Gil D. (Memory and Aging Center. Department of Neurology. University of California) ;
Miller, Bruce L. (University of California, San Francisco (UCSF)) ;
Rojas, Julio C. (Memory and Aging Center. Department of Neurology. University of California) ;
Seeley, William W. (Memory and Aging Center. Department of Neurology. University of California) ;
Boxer, Adam (Memory and Aging Center. Department of Neurology. University of California) ;
Universitat Autònoma de Barcelona
Importance: The accurate diagnosis of progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) is hampered by imperfect clinical-pathological correlations. Objective: To assess and compare the diagnostic value of the magnetic resonance parkinsonism index (MRPI) and other magnetic resonance imaging-based measures of cerebral atrophy to differentiate between PSP, CBD, and other neurodegenerative diseases. [...]
2022 - 10.1001/jamanetworkopen.2022.9588
JAMA network open, Vol. 5 Núm. 4 (january 2022) , p. E229588
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3.
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11 p, 1.6 MB |
Prevalence, Timing, and Network Localization of Emergent Visual Creativity in Frontotemporal Dementia
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Friedberg, Adit (Global Brain Health Institute, University of California, San Francisco, and Trinity College Dublin, Dublin, Ireland) ;
Pasquini, Lorenzo (Neuroscape, University of California, San Francisco) ;
Diggs, Ryan (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Glaubitz, Erika A. (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Lopez, Lucia (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Illán-Gala, Ignacio (Institut de Recerca Sant Pau) ;
Iaccarino, Leonardo (now with Eli Lilly and Company, Philadelphia, Pennsylvania) ;
La Joie, Renaud (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Mundada, Nidhi (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Knudtson, Marguerite (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Neylan, Kyra (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Brown, Jesse (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Allen, Isabel (Global Brain Health Institute, University of California, San Francisco, and Trinity College Dublin, Dublin, Ireland) ;
Rankin, Katherine P. (Global Brain Health Institute, University of California, San Francisco, and Trinity College Dublin, Dublin, Ireland) ;
Bonham, Luke W. (Department of Radiology and Biomedical Imaging, University of California, San Francisco) ;
Yokoyama, Jennifer S. (Department of Radiology and Biomedical Imaging, University of California, San Francisco) ;
Ramos, Eliana M. (Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles) ;
Geschwind, Daniel H. (Institute for Precision Health, University of California, Los Angeles) ;
Spina, Salvatore (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Grinberg, Lea T. (Department of Pathology, University of California, San Francisco) ;
Miller, Zachary A. (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Kramer, Joel H. (University of California. Department of Neurology) ;
Rosen, Howard (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Gorno-Tempini, Maria Luisa (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Rabinovici, Gil (Associate Editor, JAMA Neurology) ;
Seeley, William W. (Department of Pathology, University of California, San Francisco) ;
Miller, Bruce L. (Global Brain Health Institute, University of California, San Francisco, and Trinity College Dublin, Dublin, Ireland) ;
Universitat Autònoma de Barcelona
This case-control study assesses the anatomical and physiological underpinnings of visual artistic creativity in individuals with frontotemporal dementia. What are the neural underpinnings of visual artistic creativity (VAC) in the setting of frontotemporal dementia (FTD)? In this study of 119 patients, VAC occurred early in the course of FTD, was disproportionately observed in patients with temporal lobe-predominant degeneration, and may be associated with damage to brain regions that normally suppress dorsomedial occipital cortex function. [...]
2023 - 10.1001/jamaneurol.2023.0001
JAMA Neurology, Vol. 80 (february 2023) , p. 377-387
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4.
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13 p, 2.1 MB |
Sex differences in the behavioral variant of frontotemporal dementia : A new window to executive and behavioral reserve
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Illán-Gala, Ignacio (Institut d'Investigació Biomèdica Sant Pau) ;
Casaletto, Kaitlin B. (University of California) ;
Borrego-Écija, Sergi (Universitat de Barcelona) ;
Arenaza-Urquijo, Eider (Fundació Pasqual Maragall) ;
Wolf, Amy (University of California) ;
Cobigo, Yann (University of California) ;
Goh, Sheng Yang M. (University of California) ;
Staffaroni, Adam M. (University of California) ;
Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ;
Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau) ;
Blesa, Rafael (Institut d'Investigació Biomèdica Sant Pau) ;
Clarimón, Jordi (Institut d'Investigació Biomèdica Sant Pau) ;
Iulita, M. Florencia (Women's Brain Project) ;
Brugulat-Serrat, Anna (Fundació Pasqual Maragall) ;
Llado Plarrumani, Albert (Universitat de Barcelona) ;
Grinberg, Lea T. (University of California) ;
Possin, Katherine (University of California) ;
Rankin, Katherine P. (University of California) ;
Kramer, Joel H. (University of California) ;
Rabinovici, Gil D. (University of California) ;
Boxer, Adam (University of California) ;
Seeley, William W. (University of California) ;
Sturm, Virginia E. (University of California) ;
Gorno-Tempini, Maria Luisa (University of California) ;
Miller, Bruce L. (University of California) ;
Sanchez-Valle, Raquel (Universitat de Barcelona) ;
Perry, David C. (University of California) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Rosen, Howard J. (University of California) ;
Universitat Autònoma de Barcelona
Biological sex is an increasingly recognized factor driving clinical and structural heterogeneity in Alzheimer's disease, but its role in the behavioral variant of frontotemporal dementia (bvFTD) is unknown. [...]
2021 - 10.1002/alz.12299
Alzheimer's & Dementia, Vol. 17 (february 2021) , p. 1329-1341
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5.
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14 p, 1.2 MB |
Diagnostic Utility of Measuring Cerebral Atrophy in the Behavioral Variant of Frontotemporal Dementia and Association With Clinical Deterioration
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Illán-Gala, Ignacio (Institut d'Investigació Biomèdica Sant Pau) ;
Falgàs, Neus (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Friedberg, Adit (University of California. Department of Neurology) ;
Castro-Suárez, Sheila (University of California. Department of Neurology) ;
Keret, Ophir (University of California. Department of Neurology) ;
Rogers, Nicole (University of California. Department of Neurology) ;
Oz, Didem (University of California. Department of Neurology) ;
Nigro, Salvatore (Magna Graecia University (Catanzaro, Itàlia). Neuroscience Centre) ;
Quattrone, Andrea (Magna Graecia University (Catanzaro, Itàlia). Institute of Neurology) ;
Quattrone, Aldo (Institute of Molecular Bioimaging and Physiology (Catanzaro, Itàlia)) ;
Wolf, Amy (University of California. Department of Neurology) ;
Younes, Kyan (University of California. Department of Neurology) ;
Santos-Santos, Miguel (Institut d'Investigació Biomèdica Sant Pau) ;
Borrego-Écija, Sergi (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Cobigo, Yann (University of California. Department of Neurology) ;
Dols Icardo, Oriol (Institut d'Investigació Biomèdica Sant Pau) ;
Llado Plarrumani, Albert (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Sanchez-Valle, Raquel (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Clarimón, Jordi (Institut d'Investigació Biomèdica Sant Pau) ;
Blesa, Rafael (Institut d'Investigació Biomèdica Sant Pau) ;
Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ;
Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Grinberg, Lea T. (University of California. Department of Neurology) ;
Spina, Salvatore (University of California. Department of Neurology) ;
Kramer, Joel H. (University of California. Department of Neurology) ;
Rabinovici, Gil D. (University of California. Department of Neurology) ;
Boxer, Adam (University of California. Department of Neurology) ;
Gorno Tempini, Maria Luisa (University of California. Department of Neurology) ;
Miller, Bruce L. (University of California. Department of Neurology) ;
Seeley, William W. (University of California. Department of Neurology) ;
Rosen, Howard J. (University of California. Department of Neurology) ;
Perry, David C. (University of California. Department of Neurology) ;
Universitat Autònoma de Barcelona
Can widely available measures of atrophy on magnetic resonance imaging increase diagnostic certainty of underlying frontotemporal lobar degeneration (FTLD) and estimate clinical deterioration in the behavioral variant of frontotemporal dementia (bvFTD)? This diagnostic/prognostic study investigated the clinical utility of 5 validated visual atrophy scales (VAS) and the Magnetic Resonance Parkinsonism Index. [...]
2021 - 10.1001/jamanetworkopen.2021.1290
JAMA network open, Vol. 4 (march 2021)
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6.
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10 p, 1.3 MB |
Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia
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Bonham, Luke W. (University of California, San Francisco (UCSF)) ;
Steele, Natasha Z. R. (University of California, San Francisco (UCSF)) ;
Karch, Celeste M. (Department of Psychiatry. Washington University) ;
Broce, Iris (University of California, San Francisco (UCSF)) ;
Geier, Ethan G. (University of California, San Francisco (UCSF)) ;
Wen, Natalie L. (Department of Psychiatry. Washington University) ;
Momeni, Parastoo (Texas Tech University Health Science Center. Laboratory of Neurogenetics) ;
Hardy, John (UCL Institute of Neurology (Regne Unit). Department of Molecular Neuroscience) ;
Miller, Zachary A. (University of California, San Francisco (UCSF)) ;
Gorno-Tempini, Maria Luisa (University of California, San Francisco (UCSF)) ;
Hess, Christopher P. (University of California, San Francisco (UCSF)) ;
Lewis, Patrick (School of Pharmacy. University of Reading. Whiteknights) ;
Miller, Bruce L. (University of California, San Francisco (UCSF)) ;
Seeley, William W. (University of California, San Francisco (UCSF)) ;
Manzoni, Claudia (School of Pharmacy. University of Reading. Whiteknights) ;
Desikan, Rahul S. (University of California, San Francisco (UCSF)) ;
Baranzini, Sergio E. (University of California, San Francisco (UCSF)) ;
Ferrari, Raffaele (UCL Institute of Neurology (Regne Unit). Department of Molecular Neuroscience) ;
Yokoyama, Jennifer S. (University of California, San Francisco (UCSF)) ;
Hernandez, D. G. (UCL Institute of Neurology (Regne Unit)) ;
Nalls, M. A. (National Institute on Aging (Bethesda, Estats Units d'Amèrica)) ;
Rohrer, J. D. (Dementia Research Centre. Department of Neurodegenerative Disease. UCL Institute of Neurology) ;
Ramasamy, Adaikalavan (The Jenner Institute. University of Oxford) ;
Kwok, J. B. J. (School of Medical Sciences. University of New South Wales) ;
Dobson-Stone, Carol (School of Medical Sciences. University of New South Wales) ;
Schofield, P. R. (School of Medical Sciences. University of New South Wales) ;
Halliday, G. M. (School of Medical Sciences. University of New South Wales) ;
Hodges, J. R. (School of Medical Sciences. University of New South Wales) ;
Piguet, O. (School of Medical Sciences. University of New South Wales) ;
Bartley, L. (School of Medical Sciences. University of New South Wales) ;
Thompson, E. (Department of Paediatrics. University of Adelaide) ;
Haan, E. (Department of Paediatrics. University of Adelaide) ;
Hernández, Isabel (Institut Català de Neurociènces Aplicades) ;
Ruiz, A. (Institut Català de Neurociènces Aplicades) ;
Boada, Mercè (Institut Català de Neurociènces Aplicades) ;
Borroni, Barbara (Neurology Clinic. University of Brescia) ;
Padovani, Alessandro (Neurology Clinic. University of Brescia) ;
Cruchaga, Carlos (Hope Center. Washington University School of Medicine) ;
Cairns, Nigel J (Department of Pathology and Immunology. Washington University) ;
Benussi, Luisa (Molecular Markers Laboratory. IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli) ;
Binetti, Giuliano (MAC Memory Clinic. IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli) ;
Ghidoni, R. (Molecular Markers Laboratory. IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli) ;
Forloni, G. (Biology of Neurodegenerative Disorders. IRCCS Istituto di Ricerche Farmacologiche "Mario Negri") ;
Albani, Diego (Biology of Neurodegenerative Disorders. IRCCS Istituto di Ricerche Farmacologiche "Mario Negri") ;
Galimberti, Daniela (Fondazione Cà Granda. IRCCS Ospedale Maggiore Policlinico) ;
Fenoglio, Chiara (Fondazione Cà Granda. IRCCS Ospedale Maggiore Policlinico) ;
Serpente, M. (Fondazione Cà Granda. IRCCS Ospedale Maggiore Policlinico) ;
Scarpini, E. (Fondazione Cà Granda. IRCCS Ospedale Maggiore Policlinico) ;
Clarimón, Jordi (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Lleó, Alberto (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Blesa, Rafael (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Landqvist Waldö, M. (Unit of Geriatric Psychiatry. Department of Clinical Sciences. Lund University) ;
Nilsson, K. (Unit of Geriatric Psychiatry. Department of Clinical Sciences. Lund University) ;
Nilsson, C. (Clinical Memory Research Unit. Department of Clinical Sciences. Lund University) ;
Mackenzie, I. R. A. (Department of Pathology and Laboratory Medicine. University of British Columbia) ;
Hsiung, G. Y. R. (Division of Neurology. University of British Columbia) ;
Mann, D. M. A. (Institute of Brain. Behaviour and Mental Health. University of Manchester. Salford Royal Hospital) ;
Grafman, J. (Department of Psychology. Weinberg College of Arts and Sciences. Northwestern University) ;
Morris, C. M. (Newcastle University. Institute of Neuroscience and Institute for Ageing) ;
Attems, Johannes (Newcastle University. Institute of Neuroscience and Institute for Ageing) ;
Griffiths, T. D. (Newcastle University. Institute of Neuroscience and Institute for Ageing) ;
McKeith, I. G. (Newcastle University. Institute of Neuroscience and Institute for Ageing) ;
Thomas, A. J. (Newcastle University. Institute of Neuroscience and Institute for Ageing) ;
Pietrini, P. (IMT School for Advanced Studies. Lucca) ;
Huey, Edward D (Taub Institute. Departments of Psychiatry and Neurology. Columbia University) ;
Wassermann, E. M. (Behavioral Neurology Unit. National Insititute of Neurological Disorders and Stroke. National Insititutes of Health) ;
Baborie, A. (Department of Laboratory Medicine & Pathology. University of Alberta Edmonton) ;
Jaros, E. (Institute of Neuroscience and Institute for Ageing. Campus for Ageing and Vitality. Newcastle University) ;
Tierney, M. C. (Behavioral Neurology Unit. National Insititute of Neurological Disorders and Stroke. National Insititutes of Health) ;
Pastor, Pau (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Razquin, C. (Neurogenetics Laboratory. Division of Neurosciences. Center for Applied Medical Research. Universidad de Navarra) ;
Ortega-Cubero, S. (Neurogenetics Laboratory. Division of Neurosciences. Center for Applied Medical Research. Universidad de Navarra) ;
Alonso, E. (Clínica Universidad de Navarra) ;
Perneczky, Robert (Department of Psychiatry and Psychotherapy. Technische Universität München) ;
Diehl-Schmid, Janine (Department of Psychiatry and Psychotherapy. Technische Universität München) ;
Alexopoulos, Panagiotis (Department of Psychiatry and Psychotherapy. Technische Universität München) ;
Kurz, A. (Department of Psychiatry and Psychotherapy. Technische Universität München) ;
Rainero, Innocenzo (Neurology I. Department of Neuroscience. University of Torino. Italy. A.O. Città della Salute e della Scienza di Torino) ;
Rubino, E. (Neurology I. Department of Neuroscience. University of Torino. Italy. A.O. Città della Salute e della Scienza di Torino) ;
Pinessi, L. (Neurology I. Department of Neuroscience. University of Torino. Italy. A.O. Città della Salute e della Scienza di Torino) ;
Rogaeva, Ekaterina (University of Toronto. Tanz Centre for Research in Neurodegenerative Diseases) ;
St George Hyslop, Peter (Cambridge Institute for Medical Research) ;
Rossi, G. (Fondazione IRCCS Istituto Neurologico Carlo Besta) ;
Tagliavini, Fabrizio (Fondazione IRCCS Istituto Neurologico Carlo Besta) ;
Giaccone, Giorgio (Fondazione IRCCS Istituto Neurologico Carlo Besta) ;
Rowe, J. B. (Behavioural and Clinical Neuroscience Institute) ;
Schlachetzki, J. C. M. (University of California San Diego. Department of Cellular & Molecular Medicine) ;
Uphill, J. (UCL Institute of Neurology (Regne Unit). Department of Neurodegenerative Disease) ;
Collinge, John (UCL Institute of Neurology (Regne Unit). Department of Neurodegenerative Disease) ;
Mead, S. (UCL Institute of Neurology (Regne Unit). Department of Neurodegenerative Disease) ;
Danek, Adrian (Ludwig-Maximilians-Universität München) ;
Van Deerlin, V. M. (University of Pennsylvania Perelman School of Medicine) ;
Grossman, Murray (Department of Neurology and Penn Frontotemporal Degeneration Center. University of Pennsylvania Perelman School of Medicine) ;
Trojanowski, J. Q. (Laboratory of Neurogenetics. Institute Born-Bunge. University of Antwerp) ;
Van der Zee, Julie (Laboratory of Neurogenetics. Institute Born-Bunge. University of Antwerp) ;
Cruts, Marc (Laboratory of Neurogenetics. Institute Born-Bunge. University of Antwerp) ;
Van Broeckhoven, C. (Laboratory of Neurogenetics. Institute Born-Bunge. University of Antwerp) ;
Cappa, S. F. (Neurorehabilitation Unit. Department of Clinical Neuroscience. Vita-Salute University and San Raffaele Scientific Institute) ;
Leber, Isabelle (CNRS UMR 7225. F-75013) ;
Hannequin, D. (Service de Neurologie. Inserm U1079. CNR-MAJ. Rouen University Hospital) ;
Golfier, V. (Service de Neurologie. CH Saint Brieuc) ;
Vercelletto, M. (Service de neurologie. CHU de Nantes) ;
Brice, Alexis (CNRS UMR 7225. F-75013) ;
Nacmias, Benedetta (University of Florence. Department of Neurosciences) ;
Sorbi, Sandro (University of Florence. Department of Neurosciences) ;
Bagnoli, Silvia (University of Florence. Department of Neurosciences) ;
Piaceri, I. (University of Florence. Department of Neurosciences) ;
Nielsen, J. E. (Department of Cellular and Molecular Medicine. Section of Neurogenetics. The Panum Institute. University of Copenhagen) ;
Hjermind, L. E. (Department of Cellular and Molecular Medicine. Section of Neurogenetics. The Panum Institute. University of Copenhagen) ;
Riemenschneider, M. (Laboratory for Neurogenetics. Saarland University) ;
Mayhaus, M. (Laboratory for Neurogenetics. Saarland University) ;
Ibach, B. (Department of Psychiatry. Psychotherapy and Psychosomatics) ;
Gasparoni, G. (Laboratory for Neurogenetics. Saarland University) ;
Pichler, S. (Laboratory for Neurogenetics. Saarland University) ;
Gu, W. (Luxembourg Centre For Systems Biomedicine (LCSB). University of Luxembourg) ;
Rossor, M. N. (Dementia Research Centre. Department of Neurodegenerative Disease. UCL Institute of Neurology) ;
Fox, N. C. (Dementia Research Centre. Department of Neurodegenerative Disease. UCL Institute of Neurology) ;
Warren, J. D. (Dementia Research Centre. Department of Neurodegenerative Disease. UCL Institute of Neurology) ;
Spillantini, M. G. (University of Cambridge. Department of Clinical Neurosciences) ;
Morris, H. R. (UCL Institute of Neurology (Regne Unit). Department of Molecular Neuroscience) ;
Rizzu, P. (Tübingen Site. German Center for Neurodegenerative Diseases) ;
Heutink, Peter (Tübingen Site. German Center for Neurodegenerative Diseases) ;
Snowden, J. S. (Institute of Brain. Behaviour and Mental Health. University of Manchester. Salford Royal Hospital) ;
Rollinson, Sara (Institute of Brain. Behaviour and Mental Health. University of Manchester. Salford Royal Hospital) ;
Richardson, A. (Salford Royal Foundation Trust. Faculty of Medical and Human Sciences. University of Manchester) ;
Gerhard, A. (Institute of Brain. Behaviour and Mental Health. University of Manchester. Salford Royal Hospital) ;
Bruni, A. C. (Regional Neurogenetic Centre. ASPCZ) ;
Maletta, Raffaele (Regional Neurogenetic Centre. ASPCZ) ;
Frangipane, F. (Regional Neurogenetic Centre. ASPCZ) ;
Cupidi, C. (Regional Neurogenetic Centre. ASPCZ) ;
Bernardi, Livia (Regional Neurogenetic Centre. ASPCZ) ;
Anfossi, Maria (Regional Neurogenetic Centre. ASPCZ) ;
Gallo, M. (Regional Neurogenetic Centre. ASPCZ) ;
Conidi, Maria E. (Regional Neurogenetic Centre. ASPCZ) ;
Smirne, N. (Regional Neurogenetic Centre. ASPCZ) ;
Rademakers, Rosa (Department of Neuroscience. Mayo Clinic Jacksonville) ;
Baker, M. (Department of Neuroscience. Mayo Clinic Jacksonville) ;
Dickson, Dennis W. (Department of Neuroscience. Mayo Clinic Jacksonville) ;
Graff-Radford, N. R. (Department of Neuroscience. Mayo Clinic Jacksonville) ;
Petersen, R. C. (Department of Neurology. Mayo Clinic Rochester) ;
Knopman, D. (Department of Neurology. Mayo Clinic Rochester) ;
Josephs, K. A. (Department of Neurology. Mayo Clinic Rochester) ;
Boeve, Bradley (Department of Neurology. Mayo Clinic Rochester) ;
Parisi, J. E. (Department of Pathology. Mayo Clinic Rochester) ;
Karydas, A. M. (University of California, San Francisco (UCSF)) ;
Rosen, H. (University of California, San Francisco (UCSF)) ;
van Swieten, J. C. (Department of Medical Genetics. VU university Medical Centre) ;
Dopper, E. G. P. (Department of Medical Genetics. VU university Medical Centre) ;
Seelaar, H. (Department of Medical Genetics. VU university Medical Centre) ;
Pijnenburg, Y. A. L. (VU University Medical Centre. Department of Neurology) ;
Scheltens, Philip (VU University Medical Centre. Department of Neurology) ;
Logroscino, Giancarlo (Department of Basic Medical Sciences. Neurosciences and Sense Organs. "Aldo Moro" University of Bari) ;
Capozzo, Rosa (University of Bari) ;
Novelli, V. (Medical Genetics Unit. Fondazione Policlinico Universitario A. Gemelli) ;
Puca, A. A. (Department of Medicine and Surgery. University of Salerno) ;
Franceschi, M. (Neurology Department. IRCCS Multimedica) ;
Postiglione, A. (Department of Clinical Medicine and Surgery. University of Naples Federico II) ;
Milan, G. (Geriatric Center Frullone ASL Napoli 1 Centro) ;
Sorrentino, P. (Geriatric Center Frullone ASL Napoli 1 Centro) ;
Kristiansen, M. (UCL Genomics. Institute of Child Health (ICH). UCL) ;
Chiang, H. H. (Karolinska University Hospital and Karolinska Institutet (Suècia)) ;
Graff, C. (Karolinska University Hospital and Karolinska Institutet (Suècia)) ;
Pasquier, Florence (Université des Sciences et Technologies de Lille. Inserm 1171. DISTALZ. CHU 59000) ;
Rollin, A. (Université des Sciences et Technologies de Lille. Inserm 1171. DISTALZ. CHU 59000) ;
Deramecourt, Vincent (Université des Sciences et Technologies de Lille. Inserm 1171. DISTALZ. CHU 59000) ;
Lebouvier, Thibaud (Université des Sciences et Technologies de Lille. Inserm 1171. DISTALZ. CHU 59000) ;
Kapogiannis, D. (National Institute on Aging (NIA/NIH)) ;
Ferrucci, Luigi (National Institute on Aging (Baltimore, Estats Units d'Amèrica)) ;
Pickering-Brown, S. (University of Manchester) ;
Singleton, Andrew B (National Institute on Aging (Bethesda, Estats Units d'Amèrica)) ;
Universitat Autònoma de Barcelona
The semantic variant of primary progressive aphasia (svPPA) is a clinical syndrome characterized by neurodegeneration and progressive loss of semantic knowledge. Unlike many other forms of frontotemporal lobar degeneration (FTLD), svPPA has a highly consistent underlying pathology composed of TDP-43 (a regulator of RNA and DNA transcription metabolism). [...]
2019 - 10.1038/s41598-019-46415-1
Scientific reports, Vol. 9 Núm. 1 (january 2019) , p. 10854
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