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12 p, 1.5 MB Efficacy and safety of paricalcitol in children with stages 3 to 5 chronic kidney disease / Webb, Nicholas J. A. (Royal Manchester Children's Hospital, Manchester, UK) ; Lerner, Gary (Keck School of Medicine-Children's Hospital Los Angeles, USA) ; Warady, Bradley A. (Children's Mercy Hospital, Kansas City, USA.) ; Dell, Katherine M. (Cleveland Clinic Children's, USA) ; Greenbaum, Larry A. (Emory School of Medicine and Children's Healthcare of Atlanta, USA.) ; Ariceta, Gema (Hospital Universitari Vall d'Hebron) ; Hoppe, Bernd (University Hospital Bonn, Germany) ; Linde, Peter (AbbVie Inc., North Chicago, USA) ; Lee, Ho-Jin (AbbVie Inc., North Chicago, USA) ; Eldred, Ann (AbbVie Inc., North Chicago, USA) ; Dufek, Matthew B. (AbbVie Inc., North Chicago, USA) ; Universitat Autònoma de Barcelona
Elevated intact parathyroid hormone (iPTH) levels can contribute to morbidity and mortality in children with chronic kidney disease (CKD). We evaluated the pharmacokinetics, efficacy, and safety of oral paricalcitol in reducing iPTH levels in children with stages 3-5 CKD. [...]
2017 - 10.1007/s00467-017-3579-6
Pediatric Nephrology (Berlin, Germany), Vol. 32 (march 2017) , p. 1221-1232  

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