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Articles, 1 records found
Research literature, 1 records found
Articles 1 records found  
14 p, 1.3 MB Detection of hyper-conserved regions in hepatitis B virus X gene potentially useful for gene therapy / González, Carolina (Hospital Universitari Vall d'Hebron) ; Tabernero, David (Hospital Universitari Vall d'Hebron) ; Cortese, Maria Francesca (Hospital Universitari Vall d'Hebron) ; Gregori i Font, Josep (Roche Diagnostics SL) ; Casillas, Rosario (Hospital Universitari Vall d'Hebron) ; Riveiro Barciela, Mar (Universitat Autònoma de Barcelona. Departament de Medicina) ; Godoy, Cristina (Hospital Universitari Vall d'Hebron) ; Sopena, Sara (Hospital Universitari Vall d'Hebron) ; Rando, Ariadna (Hospital Universitari Vall d'Hebron) ; Yll, Marçal (Hospital Universitari Vall d'Hebron) ; Lopez Martinez, Rosa (Hospital Universitari Vall d'Hebron) ; Quer, Josep (Vall d'Hebron Institut de Recerca) ; Esteban, Rafael (Esteban Mur) (Universitat Autònoma de Barcelona. Departament de Medicina) ; Buti, Maria (Universitat Autònoma de Barcelona. Departament de Medicina) ; Rodríguez Frías, Francisco (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
To detect hyper-conserved regions in the hepatitis B virus (HBV) X gene (HBX) 5' region that could be candidates for gene therapy. The study included 27 chronic hepatitis B treatment-naive patients in various clinical stages (from chronic infection to cirrhosis and hepatocellular carcinoma, both HBeAg-negative and HBeAg-positive), and infected with HBV genotypes A-F and H. [...]
2018 - 10.3748/wjg.v24.i19.2095
World Journal of Gastroenterology, Vol. 24 (may 2018) , p. 2095-2107  

Research literature 1 records found  
123 p, 3.1 MB Caracterización molecular del perfil de resistencias del virus de la hepatitis C después del fallo terapéutico a antivirales de acción directa mediante secuenciación masiva / Chen, Qian ; Quer, Josep, dir. ; Perales Viejo, Celia, dir. ; Gregori i Font, Josep, dir. ; Universitat Autònoma de Barcelona. Departament de Medicina
La infección crónica por el virus de la hepatitis C constituye un problema de salud pública a nivel mundial por su contribución al desarrollo de enfermedades hepáticas avanzadas y carcinoma hepatocelular. [...]
Chronic hepatitis C infection is considered as a major public health issue worldwide due to its linkage to the development of advanced liver diseases and hepatocellular carcinoma. Currently, the availability of highly efficient and well-tolerated antiviral therapies based on combinations of direct acting antivirals (DAAs) has provided sustained virological response (SVR) in nearly 95% of patients. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2019.  

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