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11 p, 861.1 KB Tolerogenic dendritic cell-based treatment for multiple sclerosis (MS) : A harmonised study protocol for two phase i clinical trials comparing intradermal and intranodal cell administration / Willekens, Barbara (University of Antwerp. Laboratory of Experimental Hematology. Vaccine and Infectious Disease Institute) ; Presas-Rodríguez, Silvia (Universitat Autònoma de Barcelona. Departament de Medicina) ; Mansilla Lopez, Maria Jose (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Derdelinckx, Judith (University of Antwerp. Laboratory of Experimental Hematology. Vaccine and Infectious Disease Institute) ; Lee, Wai-Ping (University Hospital Antwerp (Bèlgica)) ; Nijs, Griet (University Hospital Antwerp (Bèlgica)) ; De Laere, Maxime (University of Antwerp. Laboratory of Experimental Hematology. Vaccine and Infectious Disease Institute) ; Wens, Inez (University of Antwerp . Laboratory of Experimental Hematology. Vaccine and Infectious Disease Institute) ; Cras, Patrick (University Hospital Antwerp (Bèlgica)) ; Parizel, Paul (University Hospital Antwerp (Bèlgica)) ; Van Hecke, Wim (Icometrix NV) ; Ribbens, Annemie (Icometrix NV) ; Billiet, Thibo (Icometrix NV) ; Adams, Geert (C-Clear Partners) ; Couttenye, Marie-Madeleine (University Hospital Antwerp (Bèlgica)) ; Navarro-Barriuso, Juan (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Teniente Serra, Aina (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Quirant, Bibiana (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Lopez-Diaz De Cerio, Ascensión (Clínica Universidad de Navarra) ; Inogés, Susana (Clínica Universidad de Navarra) ; Prosper, Felipe (Clínica Universidad de Navarra. Centro de Investigación Médica Aplicada) ; Kip, Anke (Lygature Utrecht) ; Verheij, Herman (Lygature Utrecht) ; Gross, Catharina C. (University of Munster. Department of Neurology) ; Wiendl, Heinz (University of Munster. Department of Neurology) ; Van Ham, Marieke (University of Amsterdam. Academic Medical Centre-AMC) ; Ten Brinke, Anja (University of Amsterdam. Academic Medical Centre-AMC) ; Barriocanal, Ana María (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Massuet-Vilamajó, Anna (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Hens, Niel (University of Antwerp. Centre for Health Economic Research and Modelling Infectious Diseases) ; Berneman, Zwi (University of Antwerp. Center for Cell Therapy and Regenerative Medicine) ; Martínez Cáceres, Eva María (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Cools, Nathalie (University Hospital Antwerp (Bèlgica)) ; Ramo-Tello, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Introduction Based on the advances in the treatment of multiple sclerosis (MS), currently available disease-modifying treatments (DMT) have positively influenced the disease course of MS. However, the efficacy of DMT is highly variable and increasing treatment efficacy comes with a more severe risk profile. [...]
2019 - 10.1136/bmjopen-2019-030309
BMJ open, Vol. 9, Issue 9 (July 2019) , art. e030309  
Detailed record - Creative Commons

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5 Gross, Ch.
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