Resultados globales: 14 registros encontrados en 0.02 segundos.
Artículos, Encontrados 10 registros
Documentos de investigación, Encontrados 4 registros
Artículos Encontrados 10 registros  
1.
20 p, 1.4 MB Anti-Inflammatory Effect of an O -2-Substituted (1-3)-β-D-Glucan Produced by Pediococcus parvulus 2.6 in a Caco-2 PMA-THP-1 Co-Culture Model / Notararigo, Sara (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Varela, Encarnación (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Otal, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Antolín, María (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Guarner, Francisco (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; López, Paloma (Margarita Salas Center for Biological Research)
Bacterial β-glucans are exopolysaccharides (EPSs), which can protect bacteria or cooperate in biofilm formation or in bacterial cell adhesion. Pediococcus parvulus 2. 6 is a lactic acid bacterium that produces an O -2-substituted (1-3)-β-D-glucan. [...]
2022 - 10.3390/ijms23031527
International journal of molecular sciences, Vol. 23 (january 2022)  
2.
12 p, 2.1 MB A fermented milk product containing B. lactis CNCM i-2494 improves the tolerance of a plant-based diet in patients with disorders of gut-brain interactions / Le Nevé, Boris (Danone Nutricia Research) ; Martinez-De la Torre, Adrian (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Tap, Julien (Danone Nutricia Research) ; Nieto Ruiz, Adoración (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Derrien, Muriel (Danone Nutricia Research) ; Cotillard, Aurélie (Danone Nutricia Research) ; Faurie, Jean-Michel (Danone Nutricia Research) ; Barba Orozco, Elizabeth (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Mego Silva, Marianela (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Dornic, Quentin (Danone Nutricia Research) ; Butler, John (Lawson Health Research Institute) ; Merino, Xavier (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Lobo, Beatriz (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Pinsach Batet, Ferran (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Pozuelo, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Santos, Javier (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ; Guarner, Francisco (Universitat Autònoma de Barcelona. Departament de Medicina) ; Manichanh, Chaysavanh (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Azpiroz Vidaur, Fernando (Universitat Autònoma de Barcelona. Departament de Medicina)
Healthy, plant-based diets, rich in fermentable residues, may induce gas-related symptoms. The aim of this exploratory study was to assess the effects of a fermented milk product, containing probiotics, on the tolerance of a healthy diet in patients with disorders of gut-brain interactions (DGBI), complaining of excessive flatulence. [...]
2021 - 10.3390/nu13124542
Nutrients, Vol. 13 Núm. 12 (december 2021) , p. 4542  
3.
13 p, 1.5 MB Evaluation of an O 2-Substituted (1-3)-β-D-Glucan, Produced by Pediococcus parvulus 2.6, in ex vivo Models of Crohn's Disease / Notararigo, Sara (Foundation Health Research Institute of Santiago de Compostela) ; Varela, Encarnación (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ; Otal, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Cristobo, Iván (Margarita Salas Biological Research Centre) ; Antolín, María (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Guarner, Francisco (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Prieto, Alicia (Margarita Salas Biological Research Centre) ; López, Paloma (Margarita Salas Biological Research Centre) ; Universitat Autònoma de Barcelona
1,3-β-glucans are extracellular polysaccharides synthesized by microorganisms and plants, with therapeutic potential. Among them, the O 2-substituted-(1-3)-β-D-glucan, synthesized by some lactic acid bacteria (LAB), has a prebiotic effect on probiotic strains, an immunomodulatory effect on monocyte-derived macrophages, and potentiates the ability of the producer strain to adhere to Caco-2 cells differentiated to enterocytes. [...]
2021 - 10.3389/fmicb.2021.621280
Frontiers in microbiology, Vol. 12 (february 2021)  
4.
10 p, 592.1 KB Antibiotics as Major Disruptors of Gut Microbiota / Ramirez, Jaime (Universidad Nacional Autónoma de México) ; Guarner, Francisco (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Bustos Fernandez, Luis (Centro Medico Bustos Fernandez (CMBF)) ; Maruy, Aldo (Hospital Arnau de Vilanova (València)) ; Sdepanian, Vera Lucia (Universidade Federal de São Paulo) ; Cohen, Henry (National School of Medicine) ; Universitat Autònoma de Barcelona
Advances in culture-independent research techniques have led to an increased understanding of the gut microbiota and the role it plays in health and disease. The intestine is populated by a complex microbial community that is organized around a network of metabolic interdependencies. [...]
2020 - 10.3389/fcimb.2020.572912
Frontiers in cellular and infection microbiology, Vol. 10 (november 2020)  
5.
20 p, 22.6 MB Differential effects of western and mediterranean-type diets on gut microbiota : a metagenomics and metabolomics approach / Barber, Claudia (Universitat Autònoma de Barcelona. Departament de Medicina) ; Mego Silva, Marianela (Universitat Autònoma de Barcelona. Departament de Medicina) ; Sabater, Carlos (Instituto de Investigación Sanitaria del Principado de Asturias) ; Vallejo, Fernando (Centro de Edafologia y Biologia Aplicada del Segura-CSIC) ; Bendezú García, Rogger Álvaro (Universitat Autònoma de Barcelona. Departament de Medicina) ; Masihy, Marcela (Universitat Autònoma de Barcelona. Departament de Medicina) ; Guarner, Francisco (Universitat Autònoma de Barcelona. Departament de Medicina) ; Espín, Juan Carlos (Centro de Edafologia y Biologia Aplicada del Segura-CSIC) ; Margolles, Abelardo (Instituto de Investigación Sanitaria del Principado de Asturias) ; Azpiroz Vidaur, Fernando (Hospital Universitari Vall d'Hebron. Institut de Recerca)
Our aim was to determine the effect of diet on gut microbiota, digestive function and sensations, using an integrated clinical, metagenomics and metabolomics approach. We conducted a cross-over, randomised study on the effects of a Western-type diet versus a fibre-enriched Mediterranean diet. [...]
2021 - 10.3390/nu13082638
Nutrients, Vol. 13 Núm. 8 (august 2021) , p. 2638  
6.
9 p, 2.1 MB Dysbiosis and relapse-related microbiome in inflammatory bowel disease : a shotgun metagenomic approach / Serrano-Gómez, Gerard (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Mayorga, Luis (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Oyarzun, Iñigo (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Roca, Joaquim (Spanish National Research Council (CSIC), Barcelona, Spain) ; Borruel, Natalia (Hospital Universitari Vall d'Hebron) ; Casellas, Francesc (Hospital Universitari Vall d'Hebron) ; Varela, Encarna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Pozuelo, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Machiels, Kathleen (Translational Research Center for Gastrointestinal Disorders, Leuven, Belgium) ; Guarner, Francisco (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Vermeire, Severine (University Hospitals Leuven (Bèlgica)) ; Manichanh, Chaysavanh (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ; Universitat Autònoma de Barcelona
Crohn's disease (CD) and ulcerative colitis (UC), the two main forms of inflammatory bowel disease (IBD), affect several million people worldwide. CD and UC are characterized by periods of clinical remission and relapse. [...]
2021 - 10.1016/j.csbj.2021.11.037
Computational and Structural Biotechnology Journal, Vol. 19 (december 2021) , p. 6481-6489  
7.
7 p, 797.7 KB Abdominal distension after eating lettuce : The role of intestinal gas evaluated in vitro and by abdominal CT imaging / Barba Orozco, Elizabeth (Hospital Universitari Vall d'Hebron) ; Sánchez, Borja (Instituto de Investigación Sanitaria del Principado de Asturias) ; Burri, Emanuel (Kantonsspital Baselland) ; Accarino, Ana María (Universitat Autònoma de Barcelona. Departament de Medicina) ; Monclus, Eva (Universitat Politècnica de Catalunya) ; Navazo, Isabel (Universitat Politècnica de Catalunya) ; Guarner, Francisco (Universitat Autònoma de Barcelona. Departament de Medicina) ; Margolles, Abelardo (Instituto de Investigación Sanitaria del Principado de Asturias) ; Azpiroz Vidaur, Fernando (Universitat Autònoma de Barcelona. Departament de Medicina)
Some patients complain that eating lettuce, gives them gas and abdominal distention. Our aim was to determine to what extent the patients' assertion is sustained by evidence. An in vitro study measured the amount of gas produced during the process of fermentation by a preparation of human colonic microbiota (n = 3) of predigested lettuce, as compared to beans, a high gas-releasing substrate, to meat, a low gas-releasing substrate, and to a nutrient-free negative control. [...]
2019 - 10.1111/nmo.13703
Neurogastroenterology and Motility, Vol. 31 (august 2019)  
8.
12 p, 2.8 MB Gut microbiota linked to sexual preference and HIV infection / Noguera-Julian, Marc (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Rocafort, Muntsa (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Guillén, Yolanda (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Rivera, Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Casadellà, Maria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Nowak, Piotr (Karolinska Universitetssjukhuset) ; Hildebrand, Falk (European Molecular Biology Laboratory) ; Zeller, Georg (European Molecular Biology Laboratory) ; Parera, Mariona (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Bellido, Rocío (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Rodríguez, Cristina (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Carrillo, Jorge (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Mothe, Beatriz (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Coll, Josep (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Bravo, Isabel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Estany Quera, Carla (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Herrero, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Saz, Jorge (BCN Checkpoint) ; Sirera, Guillem (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Torrela, Ariadna (Hospital Universitari Vall d'Hebron) ; Navarro, Jordi (Hospital Universitari Vall d'Hebron) ; Crespo Casal, Manuel (Hospital Universitari Vall d'Hebron) ; Brander, Christian (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Negredo Puigmal, Eugènia (Universitat de Vic) ; Blanco, Julià (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Guarner, Francisco (Hospital Universitari Vall d'Hebron) ; Calle, Maria Luz (Universitat de Vic) ; Bork, Peer (European Molecular Biology Laboratory) ; Sönnerborg, Anders (Karolinska Universitetssjukhuset) ; Clotet Sala, Bonaventura (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Paredes, Roger (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa)
The precise effects of HIV-1 on the gut microbiome are unclear. Initial cross-sectional studies provided contradictory associations between microbial richness and HIV serostatus and suggested shifts from Bacteroides to Prevotella predominance following HIV-1 infection, which have not been found in animal models or in studies matched for HIV-1 transmission groups. [...]
2016 - 10.1016/j.ebiom.2016.01.032
EBioMedicine, Vol. 5 (March 2016) , p. 135-146  
9.
7 p, 257.9 KB Digestive Symptoms in Healthy People and Subjects With Irritable Bowel Syndrome / Azpiroz Vidaur, Fernando (Universitat Autònoma de Barcelona. Departament de Medicina) ; Guyonnet, Denis (Danone Research) ; Donazzolo, Yves (Eurofins Optimed) ; Gendre, David (Biorfortis) ; Tanguy, Jérôme (Danone Research) ; Guarner, Francisco (Universitat Autònoma de Barcelona. Departament de Medicina)
The aim of this study was to validate the ability of symptom frequency questionnaire to differentiate between irritable bowel syndrome (IBS) patients and healthy subjects. A digestive symptom frequency questionnaire (DSFQ) was previously used in a food efficacy trial in a non-IBS population with mild gastrointestinal symptoms. [...]
2015 - 10.1097/MCG.0000000000000178
Journal of Clinical Gastroenterology, Vol. 49 (july 2015) , p. e64-e70  
10.
8 p, 1.0 MB Anal gas evacuation and colonic microbiota in patients with flatulence : effect of diet / Manichanh, Chaysavanh (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Eck, Anat (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Varela, Encarna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Roca, Joaquim (Molecular Biology Institute of Barcelona, Consejo Superior de Investigaciones Cientificas) ; Clemente, José C. (University of Colorado at Boulder, and Howard Hughes Medical Institute) ; González, Antonio (University of Colorado at Boulder, and Howard Hughes Medical Institute) ; Knights, Dan (University of Colorado at Boulder, and Howard Hughes Medical Institute) ; Knight, Rob (University of Colorado at Boulder, and Howard Hughes Medical Institute) ; Estrella, Sandra (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Hernandez, Carlos (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Guyonnet, Denis (Danone Research) ; Accarino, Ana María (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Santos, Javier (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Malagelada, Juan-R (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Guarner, Francisco (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Azpiroz Vidaur, Fernando (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
To characterise the influence of diet on abdominal symptoms, anal gas evacuation, intestinal gas distribution and colonic microbiota in patients complaining of flatulence. Patients complaining of flatulence (n=30) and healthy subjects (n=20) were instructed to follow their usual diet for 3 days (basal phase) and to consume a high-flatulogenic diet for another 3 days (challenge phase). [...]
2013 - 10.1136/gutjnl-2012-303013
Gut, Vol. 63 (june 2013) , p. 401-408  

Documentos de investigación Encontrados 4 registros  
1.
137 p, 3.7 MB Observational study in Ulcerative Colitis to investigate the composition of the intestinal microbiota in patients in long-term remission / Herrera de Guise, Claudia ; Guarner Aguilar, Francisco, dir. ; Azpiroz Vidaur, Fernando, dir.
La colitis ulcerosa (CU) és una malaltia inflamatòria idiopàtica crònica que afecta l'intestí gros. És un dels dos trastorns principals que engloba el terme Malaltia Inflamatòria Intestinal (MII). [...]
La colitis ulcerosa (CU) es una enfermedad inflamatoria idiopática crónica que afecta el colon. Es uno de los dos trastornos principales que engloba el término Enfermedad Inflamatoria Intestinal (EII). [...]
Ulcerative colitis (UC) is a chronic idiopathic inflammatory disease that affects the large bowel. It is one of the two major disorders under the broad term of Inflammatory Bowel Disease (IBD). The etiology of UC involves an immune response to an imbalanced gut microbiota in genetically susceptible individuals, following unknown triggering events. [...]

2021  
2.
132 p, 3.4 MB Microbiota intestinal y colitis ulcerosa, abordaje metagenómico / Robles Alonso, Virginia ; Guarner, Francisco, dir. ; Universitat Autònoma de Barcelona. Departament de Medicina
Se han evidenciado cambios en la composición de la microbiota fecal en pacientes con CU en actividad frente a sanos, pero no queda claramente establecido si los cambios disbióticos son secundarios a la enfermedad o por el contrario pueden jugar cierto papel en la fisiopatología de la inflamación intestinal. [...]
There have been described changes in fecal microbiota composition in patients with UC with inflammatory activity versus healthy individual, but it is not clear whether the dysbiotic changes are secondary to the disease itself or, on the contrary, may play a role in the pathophysiology of intestinal inflammation. [...]

[Bellaterra] : Universitat Autònoma de Barcelona, 2017.  
3.
129 p, 623.3 KB Interacciones de las bacterias de la flora con el sistema inmune intestinal / Borruel, Natalia ; Guarner, Francisco, dir. (Hospital Universitari Vall d'Hebron)
La hipótesis de los estudios que constituyen esta tesis es que las bacterias no patógenas interactúan de manera cepa-específica con la mucosa intestinal humana induciendo un cambio o modulación en el patrón de secreción de citoquinas tanto en tejido normal como inflamado y que en el tejido intestinal inflamado, determinadas bacterias ejercen un efecto antiinflamatorio. [...]
The hypothesis of the studies that constitute this thesis is that nonpathogenic bacteria interact in a strain-specific manner with human intestinal mucosa inducing a change or modulation in the cytokine secretion profile both in normal and inflamed tissue and that in inflamed intestinal tissue, certain bacteria exert an anti-inflammatory effect. [...]

Bellaterra : Universitat Autònoma de Barcelona, 2006  
4.
185 p, 711.3 KB El Surfactante colónico y la hidrofobicidad de superficie : papel en la barrera mucosa del colon / Sánchez García, José Luis ; Armengol Carrasco, Manuel, dir. (Universitat Autònoma de Barcelona. Departament de Cirurgia) ; Guarner, Francisco, dir. (Hospital Universitari Vall d'Hebron)
La barrera mucosa gastrointestinal, formada por surfactante, moco y epitelio mucoso, separa la luz del tubo digestivo del medio interno. El surfactante, compuesto de fosfolípidos, condiciona propiedades de superficie a la mucosa. [...]
Gastrointestinal mucosal barrier, formed by surfactant, mucus and epithelium, separates the digestive tract lumen from the internal milieu. The surfactant, made up of phospholipids, establishes mucosal surface properties. [...]

Bellaterra : Universitat Autònoma de Barcelona, 2002  

Vea también: autores con nombres similares
1 Guarner, F.
3 Guarner, Francisco,
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