Resultats globals: 4 registres trobats en 0.02 segons.
Articles, 4 registres trobats
Articles 4 registres trobats  
1.
26 p, 4.7 MB Nanotools for sepsis diagnosis and treatment / Papafilippou, Lana (The University of Manchester. Faculty of Biology, Medicine and Health) ; Claxton, Andrew (Salford Royal Foundation Trust. Department of Critical Care) ; Dark, Paul (Manchester NIHR Biomedical Research Centre) ; Kostarelos, Kostas (Institut Català de Nanociència i Nanotecnologia) ; Hadjidemetriou, Marilena (The University of Manchester. Faculty of Biology, Medicine and Health)
Sepsis is one of the leading causes of death worldwide with high mortality rates and a pathological complexity hindering early and accurate diagnosis. Today, laboratory culture tests are the epitome of pathogen recognition in sepsis. [...]
2021 - 10.1002/adhm.202001378
Advanced Healthcare Materials, Vol. 10, issue 1 (Jan. 2021) , art. 2001378  
2.
12 p, 4.0 MB The biomolecule corona of lipid nanoparticles contains circulating cell-free DNA / Gardner, Lois (The University of Manchester. Nanomedicine Lab) ; Warrington, Jessica (The University of Manchester. Nanomedicine Lab) ; Rogan, Jane (Manchester Cancer Research Centre Biobank) ; Rothwell, Dominic G. (University of Manchester. Manchester Institute Cancer Biomarker Centre) ; Brady, Ged (University of Manchester. Manchester Institute Cancer Biomarker Centre) ; Dive, Caroline (University of Manchester. Manchester Institute Cancer Biomarker Centre) ; Kostarelos, Kostas (Institut Català de Nanociència i Nanotecnologia) ; Hadjidemetriou, Marilena (University of Manchester. Nanomedicine Lab.)
The spontaneous adsorption of biomolecules onto the surface of nanoparticles (NPs) in complex physiological biofluids has been widely investigated over the last decade. Characterisation of the protein composition of the 'biomolecule corona' has dominated research efforts, whereas other classes of biomolecules, such as nucleic acids, have received no interest. [...]
2020 - 10.1039/d0nh00333f
Nanoscale horizons, Vol. 5, issue 11 (2020) , p. 1476-1486  
3.
24 p, 881.4 KB Nano-scavengers for blood biomarker discovery in ovarian carcinoma / Hadjidemetriou, Marilena (The University of Manchester. Nanomedicine Lab) ; Papafilippou, Lana (The University of Manchester. Nanomedicine Lab) ; Unwin, Richard D. (The University of Manchester. Division of Cardiovascular Sciences) ; Rogan, Jane (Manchester Cancer Research Centre Biobank) ; Clamp, Andrew (The University of Manchester. Manchester Cancer Research Centre) ; Kostarelos, Kostas (Institut Català de Nanociència i Nanotecnologia)
The development and implementation of biomarker-based screening tools for ovarian cancer require novel analytical platforms to enable the discovery of biomarker panels that will overcome the limitations associated with the clinically used CA-125. [...]
2020 - 10.1016/j.nantod.2020.100901
Nano Today, Vol. 34 (Oct. 2020) , art. 100901  
4.
23 p, 654.0 KB Protein corona fingerprinting to differentiate sepsis from non-infectious systemic inflammation / Papafilippou, Lana (The University of Manchester. Nanomedicine Lab.) ; Claxton, Andrew (Manchester Academic Health Science Centre. Centre for Acute Care Trauma) ; Dark, Paul (Manchester Academic Health Science Centre. Centre for Acute Care Trauma) ; Kostarelos, Kostas (Institut Català de Nanociència i Nanotecnologia) ; Hadjidemetriou, Marilena (University of Manchester. Nanomedicine Lab.)
Rapid and accurate diagnosis of sepsis remains clinically challenging. The lack of specific biomarkers that can differentiate sepsis from non-infectious systemic inflammatory diseases often leads to excessive antibiotic treatment. [...]
2020 - 10.1039/d0nr02788j
Nanoscale, Vol. 12, issue 18 (2020) , p. 10240-10253  

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