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14 p, 17.9 MB Involvement of Cellular Prion Protein in α-Synuclein Transport in Neurons / Urrea, Laura (Barcelona, Spain) ; Segura-Feliu, Miriam (Barcelona, Spain) ; Masuda-Suzukake, Masami (Setagaya-ku, Tokyo, 156-8506 Japan) ; Hervera Abad, Arnau (Barcelona, Spain) ; Pedraz, Lucas (Barcelona, Spain) ; García Aznar, José Manuel (Zaragoza, Spain) ; Vila Bover, Miquel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Samitier, Josep (Madrid, Spain) ; Torrents, Eduard (Barcelona, Spain) ; Ferrer, Isidro (Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Barcelona, Spain) ; Gavín, Rosalina (Barcelona, Spain) ; Hagesawa, Masato (Setagaya-ku, Tokyo, 156-8506 Japan) ; del Río, José Antonio (Barcelona, Spain) ; Universitat Autònoma de Barcelona
The cellular prion protein, encoded by the gene Prnp, has been reported to be a receptor of β-amyloid. Their interaction is mandatory for neurotoxic effects of βamyloid oligomers. In this study, we aimed to explore whether the cellular prion protein participates in the spreading of α-synuclein. [...]
2017 - 10.1007/s12035-017-0451-4
Molecular neurobiology, Vol. 55 (february 2017) , p. 1847-1860  

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