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24 p, 1.4 MB |
Ischaemic conditioning and targeting reperfusion injury : a 30 year voyage of discovery
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Hausenloy, Derek J. (National Heart Research Institute Singapore) ;
Barrabés, José A.. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Bøtker, Hans Erik (Aarhus University Hospital (Aarhus, Dinamarca)) ;
Davidson, Sean M. (University College London) ;
Di Lisa, Fabio (University of Padova, Italy) ;
Downey, James (University of South Alabama, Mobile) ;
Engstrom, Thomas (Copenhagen University Hospital) ;
Ferdinandy, Péter (Pharmahungary Group, Szeged, Hungary) ;
Carbrera-Fuentes, Hector A. (Kazan Federal University, Russian Federation) ;
Heusch, Gerd (University of Essen Medical School, Germany) ;
Ibanez, Borja (Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz) ;
Iliodromitis, Efstathios K. (National and Kapodistrian University of Athens, Greece) ;
Inserte, Javier (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Jennings, Robert (Duke University, Durham, NC USA) ;
Kalia, Neena (University of Birmingham, UK) ;
Kharbanda, Rajesh (Oxford University Hospitals, UK) ;
Lecour, Sandrine (University of Cape Town, South Africa) ;
Marber, Michael (St. Thomas' Hospital, London, UK) ;
Miura, Tetsuji (Sapporo Medical University School of Medicine, Japan) ;
Ovize, Michel (Université Claude Bernard, Lyon 1, France) ;
Perez-Pinzon, Miguel A. (University of Miami Miller School of Medicine, USA) ;
Piper, Hans Michael (Carl von Ossietzky Universität Oldenburg) ;
Przyklenk, Karin (Wayne State University, Detroit, USA) ;
Schmidt, Michael Rahbek (Duke-National University of Singapore) ;
Redington, Andrew (Cincinnati Children's Hospital Medical Center) ;
Ruiz Meana, Marisol (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Vilahur, Gemma (Institut d'Investigació Biomèdica Sant Pau) ;
Vinten-Johansen, Jakob (Emory University, Atlanta, USA) ;
Yellon, Derek M. (The National Institute of Health Research University College London Hospitals Biomedical Research Centre, London, UK) ;
García-Dorado, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
To commemorate the auspicious occasion of the 30th anniversary of IPC, leading pioneers in the field of cardioprotection gathered in Barcelona in May 2016 to review and discuss the history of IPC, its evolution to IPost and RIC, myocardial reperfusion injury as a therapeutic target, and future targets and strategies for cardioprotection. [...]
2016 -  10.1007/s00395-016-0588-8
Basic Research in Cardiology, Vol. 111 (october 2016)
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33 p, 1.7 MB |
Cardiac MRI Endpoints in Myocardial Infarction Experimental and Clinical Trials
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Ibanez, Borja (Hospital Universitario Fundación Jiménez Díaz) ;
Aletras, Anthony H. (Skåne University Hospital (Suècia)) ;
Arai, Andrew E. (National Heart, Lung, and Blood Institute (Bethesda, Estats Units d'Amèrica)) ;
Arheden, Hakan (Skåne University Hospital (Suècia)) ;
Bax, Jeroen (Department of Cardiology, Heart Lung Center, Leiden University Medical Center, Leiden, the Netherlands) ;
Berry, Colin (University of Glasgow. Glasgow Cardiovascular Research Centre) ;
Bucciarelli-Ducci, Chiara (University of Bristol. Bristol Heart Institute) ;
Croisille, Pierre (University Lyon, UJM-Saint-Etienne, INSA, CNRS UMR 5520, INSERM U1206, CREATIS, F-42023, Saint-Etienne, France) ;
Dall'Armellina, Erica (Leeds Institute of Cardiovascular and Metabolic Medicine, Department of Biomedical Imaging Sciences, University of Leeds, Leeds, United Kingdom) ;
Dharmakumar, Rohan (Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, and Division of Cardiology, Department of Medicine, University of California, Los Angeles, California) ;
Eitel, Ingo (University Heart Center Lübeck, Medical Clinic II (Cardiology/ Angiology/Intensive Care Medicine) and German Center for Cardiovascular Research (DZHK), partner site Hamburg/Kiel/Lübeck, Lübeck, Germany) ;
Fernández-Jiménez, Rodrigo (Cardiology Department, Icahn School of Medicine at Mount Sinai, New York, New York) ;
Friedrich, Matthias G. (Department of Medicine, Heidelberg University, Heidelberg, Germany) ;
García-Dorado, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Hausenloy, Derek J. (Tecnologico de Monterrey, Centro de Biotecnologia-FEMSA, Nuevo Leon, Mexico) ;
Kim, Raymond J. (Duke Cardiovascular Magnetic Resonance Center, Division of Cardiology, and Department of Radiology, Duke University Medical Center, Durham, North Carolina) ;
Kozerke, Sebastian (Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland) ;
Kramer, Christopher M. (Departments of Medicine and Radiology, University of Virginia Health System, Charlottesville, Virginia) ;
Salerno, Michael (Departments of Medicine and Radiology, University of Virginia Health System, Charlottesville, Virginia; and) ;
Sánchez-González, Javier (Philips Healthcare, Madrid, Spain) ;
Sanz, Javier (Cardiology Department, Icahn School of Medicine at Mount Sinai, New York, New York) ;
Fuster, Valentín (Cardiology Department, Icahn School of Medicine at Mount Sinai, New York, New York) ;
Universitat Autònoma de Barcelona
After a reperfused myocardial infarction (MI), dynamic tissue changes occur (edema, inflammation, microvascular obstruction, hemorrhage, cardiomyocyte necrosis, and ultimately replacement by fibrosis). [...]
2019 - 10.1016/j.jacc.2019.05.024
Journal of the American College of Cardiology, Vol. 74 (july 2019) , p. 238-256
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6 p, 488.0 KB |
Circadian variation in acute myocardial infarct size assessed by cardiovascular magnetic resonance in reperfused STEMI patients
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Bulluck, Heerajnarain (National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore) ;
Nicholas, Jennifer (London School Hygiene and Tropical Medicine, London, UK) ;
Crimi, Gabriele (Struttura Complessa Cardiologia, Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico San Matteo, Pavia, Italy) ;
White, Steven K. (The Hatter Cardiovascular Institute, Institute of Cardiovascular Science, University College London, UK) ;
Ludman, Andrew J. (Royal Devon & Exeter Hospital (Exeter, Regne Unit)) ;
Pica, Silvia (Struttura Complessa Cardiologia, Azienda Ospedaliera SS: Antonio e Biagio, Alessandria, Italy) ;
Raineri, Claudia (Struttura Complessa Cardiologia, Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico San Matteo, Pavia) ;
Cabrera-Fuentes, H. A (Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore) ;
Yellon, Derek (The Hatter Cardiovascular Institute, Institute of Cardiovascular Science, University College London) ;
Rodriguez-Palomares, Jose (Hospital Universitari Vall d'Hebron) ;
García-Dorado, David (Hospital Universitari Vall d'Hebron) ;
Hausenloy, Derek J. (Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore) ;
Universitat Autònoma de Barcelona
Clinical studies using serum cardiac biomarkers to investigate a circadian variation in acute myocardial infarct (MI) size in ST-segment elevation myocardial infarction (STEMI) patients reperfused by primary percutaneous coronary intervention (PPCI) have produced mixed results. [...]
2017 - 10.1016/j.ijcard.2016.12.030
International Journal of Cardiology, Vol. 230 (march 2017) , p. 149-154
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11 p, 337.7 KB |
Targeting reperfusion injury in patients with ST-segment elevation myocardial infarction : trials and tribulations
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Hausenloy, Derek J. (National Institute of Health Research University College London Hospitals Biomedical Research Centre, London W1T 7DN, UK) ;
Botker, Hans Erik (Aarhus University Hospital (Aarhus, Dinamarca)) ;
Engstrom, Thomas (Copenhagen University Hospital Rigshospitalet) ;
Erlinge, David (Department of Cardiology, Lund University, Lund, Sweden) ;
Heusch, Gerd (Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School, Essen, Germany) ;
Ibanez, Borja (Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz) ;
Kloner, Robert A. (Division of Cardiovascular Medicine, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA) ;
Ovize, Michel (UMR 1060 (CarMeN), Université Claude Bernard, Lyon, France) ;
Yellon, Derek M. (National Institute of Health Research University College London Hospitals Biomedical Research Centre, London W1T 7DN, UK) ;
García-Dorado, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
2016 - 10.1093/eurheartj/ehw145
European heart journal, Vol. 38 (april 2016) , p. 935-941
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13 p, 508.4 KB |
Meeting report from the 2nd International Symposium on New Frontiers in Cardiovascular Research. Protecting the cardiovascular system from ischemia : between bench and bedside
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Cabrera-Fuentes, H. A (Escuela de Ingeniería y Ciencias, Centro de Biotecnología-FEMSA, Tecnológico de Monterrey) ;
Alba-Alba, Corina (Institute of Genetics, Univeristy of the Sea. Puerto Escondido Campus, Oaxaca Oaxacan System of State Universities (SUNEO)) ;
Aragones, Julian (Instituto de Investigación Hospital Universitario de la Princesa) ;
Bernhagen, Jürgen (Institute of Biochemistry and Molecular Cell Biology, RWTH Aachen University) ;
Boisvert, William A. (Center for Cardiovascular Research, John A. Burns School of Medicine, University of Hawaii) ;
Bøtker, Hans Erik (Aarhus University Hospital (Aarhus, Dinamarca)) ;
Cesarman-Maus, Gabriela (Department of Hematology, Instituto Nacional de Cancerología, Mexico City, Mexico) ;
Fleming, Ingrid (Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe-University, Frankfurt, Germany) ;
García-Dorado, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Lecour, Sandrine (Hatter Institute and MRC Inter-University Cape Heart Unit, Faculty of Health Sciences, University of Cape Town) ;
Liehn, Elisa (Institute for Molecular Cardiovascular Research, RWTH University Hospital Aachen) ;
Marber, Michael S. (King's College London) ;
Marina, Nephtali (Department of Clinical Pharmacology, University College London) ;
Mayr, Manuel (King's College London. The James Black Centre) ;
Perez-Mendez, Oscar (Department of Molecular Biology, National Institute of Cardiology, Mexico City) ;
Miura, Tetsuji (Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine) ;
Ruiz-Meana, Marisol (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Salinas-Estefanon, Eduardo M. (Laboratorio de Biofísica Cardiaca, Instituto de Fisiología, Universidad Autónoma de Puebla, Puebla, Mexico) ;
Ong, Sang-Bing (National Heart Research Institute Singapore, National Heart Centre Singapore) ;
Schnittler, Hans J. (Institute of Anatomy and Vascular Biology, Westfalian-Wilhelms-University, Münster) ;
Sanchez-Vega, Jose T. (Universidad Nacional Autónoma de México. Departamento de Microbiología y Parasitología) ;
Sumoza-Toledo, Adriana (Laboratorio Multidisciplinario de Ciencias Biomédicas, Instituto de Investigaciones Medico-Biológicas, Universidad Veracruzana campus Veracruz) ;
Vogel, Carl-Wilhelm (Department of Pathology, John A. Burns School of Medicine, University of Hawaii) ;
Yarullina, Dina (Department of Microbiology, Kazan Federal University, Kazan, Russian Federation) ;
Yellon, Derek M. (The National Institute of Health Research University College London Hospitals Biomedical Research Centre) ;
Preissner, Klaus T. (Institute of Biochemistry, Medical School, Justus-Liebig University, Giessen, Germany) ;
Hausenloy, Derek J. (The National Institute of Health Research University College London Hospitals Biomedical Research Centre) ;
Universitat Autònoma de Barcelona
Recent advances in basic cardiovascular research as well as their translation into the clinical situation were the focus at the last "New Frontiers in Cardiovascular Research meeting". Major topics included the characterization of new targets and procedures in cardioprotection, deciphering new players and inflammatory mechanisms in ischemic heart disease as well as uncovering microRNAs and other biomarkers as versatile and possibly causal factors in cardiovascular pathogenesis. [...]
2015 - 10.1007/s00395-015-0527-0
Basic Research in Cardiology, Vol. 111 (december 2015)
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13 p, 340.4 KB |
ESC working group cellular biology of the heart : position paper: improving the preclinical assessment of novel cardioprotective therapies
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Lecour, Sandrine (Hatter Institute for Cardiovascular Research (Àfrica)) ;
Bøtker, Hans Erik (Aarhus University Hospital (Aarhus, Dinamarca)) ;
Condorelli, Gianluigi (Instituto Clinico Humanitas (Milano, Itàlia)) ;
Davidson, Sean M. (Hatter Institute for Cardiovascular Research (Londres, Regne Unit)) ;
García-Dorado, David (Universitat Autònoma de Barcelona) ;
Engel, Felix B. (Friedrich-Alexander-Universität Erlangen-Nürnberg) ;
Ferdinandy, Péter (Semmelweis Egyetem. Department of Pharmacology and Pharmacotherapy) ;
Heusch, Gerd (Universitätsklinikum Essen) ;
Madonna, Rosalinda (Università degli Studi "G. d'Annunzio" Chieti) ;
Ovize, Michel (Université Claude Bernard Lyon 1) ;
Ruiz Meana, Marisol (Hospital Universitari Vall d'Hebron) ;
Schulz, Rainer (Justus Liebig-Universität Gießen) ;
Sluijter, Joost P. G. (Universitair Medisch Centrum Utrecht) ;
Van Laake, Linda W. (Universitair Medisch Centrum Utrecht) ;
Yellon, Derek M. (Hatter Institute for Cardiovascular Research (Londres, Regne Unit)) ;
Hausenloy, Derek J. (Hatter Institute for Cardiovascular Research (Londres, Regne Unit))
Ischaemic heart disease (IHD) remains the leading cause of death and disability worldwide. As a result, novel therapies are still needed to protect the heart from the detrimental effects of acute ischaemia-reperfusion injury, in order to improve clinical outcomes in IHD patients. [...]
2014 - 10.1093/cvr/cvu225
Cardiovascular research, Vol. 104, issue 3 (Dec. 2014) , p. 399-411
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