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8 p, 1.4 MB |
Comprehensive Characterization of the Mutational Landscape in Localized Anal Squamous Cell Carcinoma
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Trilla-Fuertes, Lucía (Biomedica Molecular Medicine SL, C/Faraday 7, 28049, Madrid, Spain) ;
Ghanem, Ismael (Medical Oncology Department, Hospital Universitario La Paz, Paseo de la Castellana 261, 28046, Madrid, Spain) ;
Maurel, Joan (Medical Oncology Department, Hospital Clinic of Barcelona, Translational Genomics and Targeted Therapeutics in Solid Tumors Group, IDIBAPS, University of Barcelona, Carrer de Villarroel 170, 08036, Barcelona, Spain) ;
G-Pastrián, Laura (Molecular Pathology and Therapeutic Targets Group, Hospital Universitario La Paz-IdiPAZ, Paseo de la Castellana 261, 28046, Madrid, Spain) ;
Mendiola, Marta (Biomedical Research Networking Center on Oncology-CIBERONC, ISCIII, Av. Monforte de Lemos 5, 28029, Madrid, Spain) ;
Peña, Cristina (Pathology Department, Hospital Universitario La Paz, Paseo de la Castellana 261, 28046, Madrid, Spain) ;
López-Vacas, Rocío (Molecular Oncology & Pathology Lab, Institute of Medical and Molecular Genetics-INGEMM, Hospital Universitario La Paz-IdiPAZ, Paseo de la Castellana 261, 28046, Madrid, Spain) ;
Prado-Vázquez, Guillermo (Biomedica Molecular Medicine SL, C/Faraday 7, 28049, Madrid, Spain) ;
López-Camacho, Elena (Molecular Oncology & Pathology Lab, Institute of Medical and Molecular Genetics-INGEMM, Hospital Universitario La Paz-IdiPAZ, Paseo de la Castellana 261, 28046, Madrid, Spain) ;
Zapater-Moros, Andrea (Molecular Oncology & Pathology Lab, Institute of Medical and Molecular Genetics-INGEMM, Hospital Universitario La Paz-IdiPAZ, Paseo de la Castellana 261, 28046, Madrid, Spain) ;
Heredia, Victoria (Translational Oncology Lab, Hospital Universitario La Paz-IdiPAZ, Paseo de la Castellana 261, 28046, Madrid, Spain) ;
Cuatrecasas, Miriam (Pathology Department, Hospital Clínic Universitari de Barcelona, Carrer de Villarroel 170, 08036, Barcelona, Spain) ;
García-Alfonso, Pilar (Hospital General Universitario Gregorio Marañón) ;
Capdevila, Jaume (Vall d'Hebron Institut d'Oncologia) ;
Conill, Carles (Radiotherapy Oncology Department, Hospital Clínic Universitari de Barcelona, Carrer de Villarroel 170, 08036, Barcelona, Spain) ;
García-Carbonero, Rocío (Medical Oncology Department, Hospital Universitario 12 de Ocubre, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), UCM, CNIO, CIBERONC, Av. Córdoba s/n, 28041, Madrid, Spain) ;
Heath, Karen E. (Institute of Medical and Molecular Genetics, IdiPAZ, Hospital Universitario La Paz /& CIBERER, Unit 753, ISCIII, Paseo de la Castellana 261, 28046, Madrid, Spain) ;
Ramos-Ruiz, Ricardo (Genomics Unit Cantoblanco, Parque Científico de Madrid, C/ Faraday 7, 28049, Madrid, Spain) ;
Llorens, Carlos (Biotechvana SL, Parque Científico de Madrid, C/ Faraday 7, 28049, Madrid, Spain) ;
Campos-Barros, Ángel (Institute of Medical and Molecular Genetics, IdiPAZ, Hospital Universitario La Paz /& CIBERER, Unit 753, ISCIII, Paseo de la Castellana 261, 28046, Madrid, Spain) ;
Gámez-Pozo, Angelo (Molecular Oncology & Pathology Lab, Institute of Medical and Molecular Genetics-INGEMM, Hospital Universitario La Paz-IdiPAZ, Paseo de la Castellana 261, 28046, Madrid, Spain) ;
Feliu, Jaime (Cátedra UAM-Amgen, Universidad Autónoma de Madrid, Ciudad Universitaria de Cantoblanco, 28049, Madrid, Spain) ;
Vara, Juan Ángel Fresno (Molecular Oncology & Pathology Lab, Institute of Medical and Molecular Genetics-INGEMM, Hospital Universitario La Paz-IdiPAZ, Paseo de la Castellana 261, 28046, Madrid, Spain)
Anal squamous cell carcinoma (ASCC) is a rare neoplasm. Chemoradiotherapy is the standard of care, with no therapeutic advances achieved over the past three decades. Thus, a deeper molecular characterization of this disease is still necessary. [...]
2020 -  10.1016/j.tranon.2020.100778
Translational Oncology, Vol. 13 (may 2020)
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13 p, 2.3 MB |
The NER-related gene GTF2H5 predicts survival in high-grade serous ovarian cancer patients
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Gayarre, Javier (Human Genetics Group, Spanish National Cancer Research Center (CNIO)) ;
Kamieniak, Marta M. (Human Genetics Group, Spanish National Cancer Research Center (CNIO)) ;
Cazorla-Jiménez, Alicia (Department of Pathology, Fundación Jiménez Díaz-IDC Salud) ;
Muñoz-Repeto, Ivan (Human Genetics Group, Spanish National Cancer Research Center (CNIO)) ;
Borrego, Salud (Biomedical Network Research Centre on Rare Diseases (CIBERER)) ;
García-Donas, Jesús (Medical Oncology Service, Oncologic Center Clara Campal) ;
Hernando, Susana (Department of Oncology, Fundación Hospital Alcorcón) ;
Robles-Díaz, Luis (Familial Cancer Unit and Medical Oncology Department, Hospital 12 de Octubre) ;
García-Bueno, José M. (Department of Oncology, Hospital General de Albacete) ;
Ramón y Cajal, Teresa (Institut d'Investigació Biomèdica Sant Pau) ;
Hernández-Agudo, Elena (Breast Cancer Clinical Research Unit, Spanish National Cancer Research Center (CNIO)) ;
Heredia Soto, Victoria (Pathology and Translational Oncology Research Laboratories, Hospital La Paz Institute for Health Research (IdiPAZ)) ;
Márquez-Rodas, Ivan (Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM)) ;
Echarri, María José (Medical Oncology Service, Hospital Severo Ochoa) ;
Lacambra-Calvet, Carmen (Department of Internal Medicine, Hospital Severo Ochoa) ;
Sáez, Raquel (Laboratory of Genetics, Hospital Donostia) ;
Cusidó, Maite (Department of Obstetrics and Gynecology, Hospital Universitario Quirón-Dexeus) ;
Redondo, Andrés (Department of Medical Oncology, Hospital La Paz IdiPAZ, Madrid) ;
Paz-Ares, Luis (Medical Oncology Service, Hospital 12 de Octubre) ;
Hardisson, David (Pathology Research Laboratory, Department of Pathology, Hospital La Paz IdiPAZ, and Facultad de Medicina, Universidad Autónoma de Madrid) ;
Mendiola, Marta (Pathology and Translational Oncology Research Laboratories, Hospital La Paz Institute for Health Research (IdiPAZ)) ;
Palacios, José (Department of Pathology, Hospital Universitario Ramón y Cajal) ;
Benítez, Javier (Biomedical Network Research Centre on Rare Diseases (CIBERER)) ;
García, María José (Biomedical Network Research Centre on Rare Diseases (CIBERER)) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
We aimed to evaluate the prognostic and predictive value of the nucleotide excision repair-related gene GTF2H5, which is localized at the 6q24. 2-26 deletion previously reported by our group to predict longer survival of high-grade serous ovarian cancer patients. [...]
2015 - 10.3802/jgo.2016.27.e7
Journal of Gynecologic Oncology, Vol. 27 (november 2015)
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